COLUMBIA, Mo. – While there are many benefits of losing weight, weight reduction also might negatively affect bones in the body. During weight loss, bones are being remodeled - breaking down old bone and forming new bone - at an accelerated rate. As a result, bone density is reduced, causing increased fragility. In a new study, University of Missouri researchers found that weight-bearing exercise, in this case, fast walking or jogging, did not prevent the increased bone turnover caused by weight loss.