Body

Average C-reactive protein (CRP) values vary in diverse populations — possibly impacting how doctors estimate cardiovascular risk and determine statin treatment, according to a new study in Circulation: Cardiovascular Genetics, a journal of the American Heart Association.

DETROIT – The old saying, "never put anything smaller than your elbow in your ear," couldn't be truer for a patient who experienced vertigo and severe hearing loss after a cotton swab perforated her eardrum and damaged her inner ear.

But what makes this patient's case unique is that otolaryngologists at Henry Ford Hospital in Detroit were not only able to alleviate her vertigo with surgery, but restore her hearing – an extremely rare occurrence.

Washington, D.C. (September 28, 2010) -- A new disposable device based on advances in microfluidics may help identify advanced breast cancer patients who are candidates for therapy with the drug trastuzumab (Herceptin). The device is described in the American Institute of Physics' journal Biomicrofluidics.

DENVER — Patients with triple-negative breast cancer, one of the hardest subtypes to treat, may have a unique biomarker that would enable them to receive more targeted therapy, according to data presented at the Fourth AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development.

Triple-negative breast cancers are breast cancers that have tested negative for estrogen receptors, progesterone receptors and HER2. Because of this biology, these cancers do not respond to endocrine therapies or trastuzumab.

PHOENIX, Ariz. — Sept. 28, 2010 — The loss of a gene known as INPP5A could predict the onset, and track the progression, of an aggressive type of skin cancer, according to a study published today by the Arizona Cancer Center, Mayo Clinic and the Translational Genomics Research Institute (TGen).

Targeting INPP5A could provide physicians with better ways to prevent and treat cutaneous squamous cell carcinoma, or SCC, a skin cancer that often spreads to other parts of the body, according to a scientific paper published today in the journal Cancer Prevention Research.

DENVER — Researchers in England say they have discovered a set of biomarkers that can distinguish prostate cancer from benign prostate disease and healthy tissue with 90 percent accuracy. This preliminary data, if validated in larger ongoing studies, could be developed into a serum protein test that reduces the number of unnecessary biopsies and identifies men who need treatment before symptoms begin.

DENVER — Using a novel aptamer-based proteomics array technology, researchers and collaborators have identified biomarkers and protein signatures that are hallmarks of cancer at an early stage for two of the most aggressive and deadly forms of cancer — pancreatic and mesothelioma.

This technology would enable better clinical diagnosis at an earlier stage and may provide insight into new therapeutic targets, said Rachel Ostroff, Ph.D., clinical research director of Somalogic Inc.

(Boston) - Researchers from Boston Medical Center (BMC) and Boston University School of Public Health (BUSPH) have found that individuals who do not speak English at home are less likely to receive colorectal cancer screenings (CRC) as compared to those who do speak English at home. The findings, which currently appear on-line in the Journal of General Internal Medicine, suggest that patient-provider language barriers play a role in health-care disparities, and that providers should promote the importance of CRC screening to non-English speaking patients.

Melbourne, Australia—September 28, 2010— In recent years, several guidelines in the treatment of posttraumatic stress disorder have been put into practice globally. Practice guidelines across the health sphere are very important in guiding the care people receive. Although there is a high level of consensus on these guidelines among practitioners, there are also differences that can lead to confusion among providers, patients, and purchasers of mental health services for people affected by trauma.

WEST LAFAYETTE, Ind. - Researchers have created a computer model that predicts how a disaster's impact on critical infrastructure would affect a city's social and economic fabric, a potential tool to help reduce the severity of impacts, manage the aftermath of catastrophe and fortify infrastructure against future disasters.

Being allergic to dogs or cats may worsen your ragweed allergies, according to a study from Queen's University.

Researchers found that people with pet allergies often develop ragweed allergy symptoms more quickly than others. But the study also suggests that once allergy season is in full swing, those symptom differences subside.

Social rejection isn't just emotionally upsetting; it also upsets your heart. A new study finds that being rejected by another person makes your heart rate drop for a moment. The study is published in Psychological Science, a journal of the Association for Psychological Science.

Research has shown that the brain processes physical and social pain in some of the same regions. Bregtje Gunther Moor, Eveline A. Crone, and Maurits W. van der Molen of the University of Amsterdam and Leiden University in the Netherlands wanted to find out how social pain affects you physically.

The protein could provide a target to develop new treatments for the disease or enable earlier diagnosis, say the researchers from Barts and The London School of Medicine and Dentistry. Pancreatic cancer has the lowest survival rate of all cancers due to its lack of symptoms in the early stages, late diagnosis and its resistance to chemotherapy and radiation therapy.

A Wildlife Conservation Society (WCS) study on nesting birds in Argentina finds that increasing temperatures and rainfall—both side effects of climate change in some parts of the world—could be bad for birds of South America, but great for some of their parasites which thrive in warmer and wetter conditions.

DENVER — Circulating tumor cells (CTCs) may be a promising alternative, noninvasive source of tumor materials for biomarker assessment, according to data presented at the Fourth AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development.