Body

Studying the metabolome of smokers, Lombardi researchers find early signs of damage

Philadelphia, Pa. – Examining the blood "metabolomics" profile of smokers immediately after they had a cigarette revealed activation of pathways involved in cell death, inflammation, and other forms of systemic damage, say researchers at Georgetown Lombardi Comprehensive Cancer Center, part of Georgetown University Medical Center.

Most hysterectomies should be performed vaginally or laparoscopically

Philadelphia, PA, November 7, 2010 – Approximately 600,000 hysterectomies are performed in the United States annually to treat benign disorders of the pelvis. More than two-thirds are performed through an abdominal incision.

Family health history as gold standard in disease risk assessment validated

Family health history as gold standard in disease risk assessment validated

BETHESDA, MD – October 22, 2010 – Thousands of the world's top scientists and clinicians in the human genetics field will convene to present their latest research findings at the American Society of Human Genetics 60th Annual Meeting, which will be held November 2-6, 2010, in Washington, D.C.

New snub-nosed monkey discovered in Northern Myanmar

New snub-nosed monkey discovered in Northern Myanmar

An international team of primatologists have discovered a new species of monkey in Northern Myanmar (formerly Burma.) The research, published in the American Journal of Primatology, reveals how Rhinopithecus strykeri, a species of snub-nosed monkey, has an upturned nose which causes it to sneeze when it rains.

Johns Hopkins researchers reshape basic understanding of cell division

By tracking the flow of information in a cell preparing to split, Johns Hopkins scientists have identified a protein mechanism that coordinates and regulates the dynamics of shape change necessary for division of a single cell into two daughter cells.

The protein, called 14-3-3, sits at an intersection where it integrates converging signals from within the cell and cues cell shape change and, ultimately, the splitting that allows for normal and abnormal cell growth, such as in tumors.

Understanding diabetes at the molecular level

United States and Japanese researchers have identified a key step in metabolic pathways linked to diabetes and cancer. The study on activation of the protein complex TORC 2 was published online in the journal Current Biology Oct. 28.

TORC 2 activates a protein called Akt, which plays a crucial role in how cells respond to insulin, said Kazuo Shiozaki, professor of microbiology in the College of Biological Sciences at UC Davis and senior author on the paper.

Kinesin - 'prima donna' protein works best alone

Kinesin - 'prima donna' protein works best alone

Computer model says human evolution date should be pushed back 3 million years

Evolutionary divergence of humans from chimpanzees likely occurred some 8 million years ago rather than the 5 million year estimate accepted by scientists, a new model suggests.

The revised estimate of when the human species parted ways from its closest primate relatives should enable scientists to better interpret the history of human evolution, said Robert D. Martin, curator of biological anthropology at the Field Museum, and a co-author of the new study appearing in the journal Systematic Biology.

Ironically, religious ritual shaped evolution of Mexican cavefish resistance to toxin

COLLEGE STATION, Nov. 4, 2010 — A centuries-old religious ceremony of an indigenous people in southern Mexico has led to evolutionary changes in a local species of fish, according to researchers from Texas A&M University.

ASHG 2010: New research on implications of direct-to-consumer and clinical genetic testing

BETHESDA, MD – October 20, 2010 – Thousands of the world's top scientists and clinicians in the human genetics field will convene to present their latest research findings at the American Society of Human Genetics 60th Annual Meeting, which will be held November 2-6, 2010, in Washington, D.C.

Real-time physician electronic alerts reduce unnecessary blood testing in elderly patients

November 5, 2010 (OAKLAND, Calif.) – An electronic message sent to physicians the moment they ordered a blood test for elderly patients reduced unnecessary use of the test that is often false-positive for the elderly, according to a paper published in the November edition of American Journal of Managed Care.

Unexpectedly small effects of mutations in bacteria bring new perspectives

Most mutations in the genes of the Salmonella bacterium have a surprisingly small negative impact on bacterial fitness. And this is the case regardless whether they lead to changes in the bacterial proteins or not. This is shown by Uppsala University scientists in an article being published today in the prestigious journal Science.

Looking older than your age may not be a sign of poor health: Study

Toronto, Ontario, November 5, 2010 – Even though most adults want to avoid looking older than their actual age, research led by St. Michael's Hospital shows that looking older does not necessarily point to poor health. The study found that a person needed to look at least 10 years older than their actual age before assumptions about their health could be made.

National study shows CT screening of former, current smokers reduces lung cancer deaths

WASHINGTON, DC – A large national study finds that screening current or former heavy smokers with a CT scan can reduce deaths from lung cancers by 20 percent. One potential reason for the reduction is that the scan can pick up tumors at an early stage. The study was conducted by the National Cancer Institute at 33 centers around the country including Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University Medical Center.

UNC team discovers promising target for new pancreatic cancer treatments

Chapel Hill, NC – One of the most frustrating problems faced by doctors who treat pancreatic cancer is the lack of effective therapeutic options. More than 38,000 people in the United States die of the disease each year, and new drugs and treatments are desperately needed.