PHILADELPHIA — Allopurinol, a relatively inexpensive anti-gout medication that has been on the market for more than 20 years, may have some activity against colorectal adenomas, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held here Nov. 7-10, 2010.
Specifically, the presence of a colorectal tumor tissue biomarker, Ki67, was markedly decreased in the preliminary results of a study of patients with colorectal polyps assigned to take allopurinol.