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Spread of TB in prisons increases the incidence of TB in the general population

The risk of tuberculosis (TB) and latent TB (in which the bacteria that cause TB lie dormant but can reactivate later to cause active TB disease) is higher in the prison population than in the general population. And importantly, the spread of TB and latent TB within prisons can substantially increase their incidence in the general population.

St. Michael's Hospital first in Ontario to implant powerful new defibrillator

TORONTO, Ont., Dec. 21, 2010 – St. Michael's Hospital today became the first in Ontario to implant a small but powerful new defibrillator into a patient's chest.

The defibrillator – about the size of a Zippo lighter – is the smallest available in terms of surface area and can deliver the highest level of energy, 40 joules.

New evidence of stem cells' pivotal role in cancer shown in Stanford study

STANFORD, Calif. — Leukemia patients whose cancers express higher levels of genes associated with cancer stem cells have a significantly poorer prognosis than patients with lower levels of the genes, say researchers at the Stanford University School of Medicine. The finding is among the first to show that the cancer stem cell hypothesis — which posits that some cancers spring from and are replenished by a small, hardy population of self-renewing cells — can be used to predict outcomes in a large group of patients and one day to tailor treatments in the clinic.

Gene alteration identified that predisposes to syndrome with high risk of cancer

Researchers have identified a new genetic alteration that predisposes individuals to Cowden syndrome, a rare disorder that is characterized by high risks of breast, thyroid and other cancers, according to preliminary research published in the December 22/29 issue of JAMA.

Prenatal supplements for moms in Nepal associated with improved functional outcomes of children

In an area where iron deficiency is prevalent, children of mothers in rural Nepal who received prenatal iron, folic acid and vitamin A supplementation performed better on measures of intellectual and motor functioning compared to offspring of mothers who received vitamin A alone, according to a study in the December 22/29 issue of JAMA.

Activity of certain stem cell genes linked with worse outcomes in acute myeloid leukemia patients

In an examination of leukemic stem cells (LSC), researchers have found that patients with acute myeloid leukemia who had higher activity of certain LSC genes had worse overall, event-free and relapse-free survival, according to a study in the December 22/29 issue of JAMA.

Prenatal micronutrient supplementation boosts children's cognition in Nepal

In developing countries where iron deficiency is prevalent, prenatal iron-folic acid supplementation increased offspring intellectual and motor functioning during school age, according to researchers from the Johns Hopkins Bloomberg School of Public Health. They examined the intellectual and motor functioning of children whose mothers received micronutrient supplementation during pregnancy and found that aspects of intellectual functioning including working memory, inhibitory control, and fine motor functioning were positively associated with prenatal iron and folic acid supplementation.

Age plays too big a role in prostate cancer treatment decisions

Older men with high-risk prostate cancer frequently are offered fewer – and less effective – choices of treatment than younger men, potentially resulting in earlier deaths, according to a new UCSF study.

The scientists found that men above age 75 with high-risk prostate cancer often are under-treated through hormone therapy or watchful waiting alone in lieu of more aggressive treatments such as surgery and radiation therapies. Instead, say the researchers, old age should not be viewed as a barrier to treatments that could lead to potential cures.

Shopping differences between sexes show evolution at work

ANN ARBOR, Mich.---The last-minute holiday dash is on: Men tend to rush in for their prized item, pay, and leave. Women study the fabrics, color, texture and price.

The hunting and gathering ritual of yesteryear continues today in malls around the world. Understanding the shopping behavior of your partner can help relieve stress at the stores, according to a researcher at the University of Michigan.

Polar bears no longer on 'thin ice': researchers say polar bears could face brighter future

 researchers say polar bears could face brighter future

before several federal agencies and the U.S. Department of the Interior, in Washington, D.C., and in 2008 the Federal government designated the polar bear as a globally threatened species.

Long-lasting chemicals threaten the environment and human health

Long-lasting chemicals threaten the environment and human health

Women war veterans face higher risk of mental health problems during pregnancy

New Rochelle, NY, December 21, 2010—Pregnancy among women veterans who served in Iraq and Afghanistan appears to increase their risk for mental health problems such as depression, anxiety, and post-traumatic stress disorder (PTSD), according to a study published in Journal of Women's Health, a peer-reviewed journal published by Mary Ann Liebert, Inc. The paper is available free online.

Top research highlighted in fight against heart disease and stroke

Research on reducing risks, improving medical treatment and improving lifestyle behaviors to fight the battle against heart disease and stroke are among the key scientific findings that make up this year's top cardiovascular and stroke research recognized by the American Heart Association/American Stroke Association.

The association has been compiling an annual list of the top 10 major advances in heart disease and stroke research since 1996. This year, for the first time, two separate lists have been compiled that highlight the top ten research advances in each respective area.

Seminal papers on election law and election administration

Seminal papers on election law and election administration

Smoking may worsen pain for cancer patients

Philadelphia, PA, December 21, 2010 – The relationship between smoking and cancer is well established. In a study published in the January 2011 issue of Pain, researchers report evidence to suggest that cancer patients who continue to smoke despite their diagnosis experience greater pain than nonsmokers. They found that for a wide range of cancer types and for cancers in stages I to IV, smoking was associated with increased pain severity and the extent to which pain interfered with a patient's daily routine.