Body

Transcriptome analysis, organ culture methods featured in Cold Spring Harbor Protocols

COLD SPRING HARBOR, N.Y. (Mon., Jan. 3, 2011) -- New technologies and methods are spurring a renaissance in the study of organogenesis. Organogenesis, essentially the process through which a group of cells becomes a functioning organ, has important connections to biological processes at the cellular and developmental levels, and its study offers great potential for medical treatments through tissue engineering approaches.

New research reveals unexpected biological pathway in glaucoma

(Baltimore, MD) — In a study published today in the Proceedings of the National Academy of Sciences (Early Edition ahead of print), a team of researchers from the Kennedy Krieger Institute and four collaborating institutions, identified a new and unexpected biological pathway that appears to contribute to the development of glaucoma and its resulting vision loss.

ATS issues statement on the treatment of pulmonary fungal infections

The American Thoracic Society has released a new official clinical policy statement on the treatment of fungal infections in adult pulmonary and critical care patients. The statement replaces ATS guidelines published in 1988, and takes into account new medications and treatment approaches, as well as provides an overview of emerging fungi.

The statement appears in the January 1, 2011, issue of the American Journal of Respiratory and Critical Care Medicine.

Mothers key to college-age women receiving HPV vaccine

COLUMBUS, Ohio -- Even after young women reach adulthood, their mothers can play a key role in convincing them to receive the human papillomavirus (HPV) vaccine, new research suggests.

A study found that college-aged women were more likely to say they had received the HPV vaccine if they had talked to their mother about it.

"Mothers talking to their daughters were an important factor in whether young women were vaccinated," said Janice Krieger, lead author of the study and assistant professor of communication at Ohio State University.

Parallels between cancers, infection suppression reported

Tiny parasitoid wasps can play an important role in controlling the populations of other insect species by laying their eggs inside the larvae of these species. A newly hatched wasp gradually eats the host alive and takes over its body.

The host insect is far from defenseless, however. In Drosophila (fruit flies), larvae activate humoral immunity in the fat body and mount a robust cellular response that encapsulates and chokes off the wasp egg.

Protein wields phosphate group to inhibit cancer metastasis

Protein wields phosphate group to inhibit cancer metastasis

HOUSTON - By sticking a chemical group to it at a specific site, a protein arrests an enzyme that may worsen and spread cancer, an international research team led by scientists at The University of Texas MD Anderson Cancer Center reports in the January issue of Nature Cell Biology.

Advancements in fertility preservation provide oncology patients new options

ROCHESTER, Minn. -- Many young people who've just learned that they have cancer also are told that the therapies that may save their lives could rob them of their ability ever to have children. Infertility caused by chemotherapy and radiation affects a sizable population: Of the 1.5 million people diagnosed with cancer in 2009, nearly 10 percent were still in their reproductive years.

Hair color of unknown offenders is no longer a secret

The hair color of an unknown perpetrator who has committed a crime will soon no longer be a secret for forensic investigators. Erasmus MC scientists, in collaboration with their Polish colleagues, have discovered that DNA can be used to predict people's probable hair color. Their findings¹ will be published today in the Springer journal Human Genetics.

Use of amniotic membrane may cause complications in strabismus surgery

Philadelphia, PA, January 3, 2011 – Postoperative adhesions are a major complication in strabismus surgery. Amniotic membrane has been used in the hopes of preventing these adhesions by forming a biological barrier during healing. In an article in the December 2010 issue of the Journal of AAPOS, the Official Publication of the American Association of Pediatric Ophthalmology and Strabismus, a team of researchers from Cairo University have discovered that the new approach may also have the opposite effect.

Eating low-fat, thanks to lupin proteins

Eating low-fat, thanks to lupin proteins

Even healthy cats act sick when their routine is disrupted

COLUMBUS, Ohio – A cat regularly vomiting hairballs or refusing to eat probably isn't being finicky or otherwise "cat-like," despite what conventional wisdom might say. There is a good chance that the cat is acting sick because of the stress caused by changes in its environment, new research suggests.

Healthy cats were just as likely as chronically ill cats to refuse food, vomit frequently and leave waste outside their litter box in response to changes in their routine, according to the Ohio State University study. Veterinary clinicians refer to these acts as sickness behaviors.

Call for truth in trans fats labeling by the FDA

Did you know that when you pick up a product promoted as trans fat free, you may still be ingesting a significant amount of this potentially harmful substance? An article by Case Western Reserve University School of Medicine student Eric Brandt, published in the January/February 2011 issue of the American Journal of Health Promotion, reveals that misleading labeling practices can result in medically significant intake of harmful trans fat, despite what you read on Food and Drug Administration (FDA) approved labels.

Tonsillectomy in children

Alexandria, VA — A multidisciplinary clinical practice guideline, "Tonsillectomy in Children" will be published in the January issue of Otolaryngology—Head and Neck Surgery (watch for a new cover and publisher in that issue of the journal). The new guideline provides evidence-based recommendations on the pre-, intra-, and postoperative care and management of children aged 1 to 18 years under consideration for tonsillectomy. Additionally, this guideline is intended for all clinicians in any setting who care for these patients.

Study shows that CPAP therapy reduces fatigue, increases energy in patients with sleep apnea

DARIEN, IL – Patients with obstructive sleep apnea often report that they feel like "a new person" after beginning treatment with continuous positive airway pressure therapy. A new study in the Jan. 1 issue of the journal SLEEP provides objective evidence to support these anecdotal reports, showing that three weeks of CPAP therapy significantly reduced fatigue and increased energy in patients with OSA.

Study finds evidence of increased lung cancer risk among tuberculosis patients

Although a clear association of tuberculosis with lung cancer remains to be established, a new study published in the January issue of the Journal of Thoracic Oncology provides compelling evidence of increased lung cancer risk among people with tuberculosis.