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Researchers create 'scoring system' for PTEN mutation testing

Monday, January 10, 2011 – Cleveland – Researchers have discovered a method for more precise identification of individuals who should undergo testing for genetic mutations of the tumor suppressor gene PTEN, which associates with a variety of conditions including several types of cancers. The research has created a diagnostic scoring system that improves on established criteria.

Minerals provide better indoor air

Minerals provide better indoor air

Species loss tied to ecosystem collapse and recovery

Species loss tied to ecosystem collapse and recovery

PROVIDENCE, R.I. [Brown University] — The world's oceans are under siege. Conservation biologists regularly note the precipitous decline of key species, such as cod, bluefin tuna, swordfish and sharks. Lose enough of these top-line predators (among other species), and the fear is that the oceanic web of life may collapse.

Early investigations promising for detecting metastatic breast cancer cells

Early investigations promising for detecting metastatic breast cancer cells

Research by engineers and cancer biologists at Virginia Tech indicate that using specific silicon microdevices might provide a new way to screen breast cancer cells' ability to metastasize.

Single cell studies identify coactivator role in fat cell maturation

HOUSTON - (Jan. 10, 2011) – All fat cells are not the same – a fact that has implications in the understanding and treatment of type 2 diabetes and obesity, said researchers from Baylor College of Medicine (www.bcm.edu) in a report that appears in the current issue of the Journal of Cell Biology (http://www.jcb.rupress.org/).

Pandemic flu strain could point way to universal vaccine

The search for a universal flu vaccine has received a boost from a surprising source: the 2009 H1N1 pandemic flu strain.

Several patients infected with the 2009 H1N1 strain developed antibodies that are protective against a variety of flu strains, scientists from Emory University School of Medicine and the University of Chicago have found. The results were published online Monday in the Journal of Experimental Medicine.

H1N1 pandemic points to vaccine strategy for multiple flu strains

Although the 2009 H1N1 influenza pandemic infected an estimated 60 million people and hospitalized more than 250,000 in the United States, it also brought one significant benefit—clues about how to make a vaccine that could protect against multiple strains of influenza.

Molecular medicine could avert predicted catastrophic vision loss in the aged

Chennai, India (January 9, 2011) - While age-related vision loss of catastrophic proportions is predicted in coming decades, rising from 17 million patients today to 55 million by the year 2050, it's possible this catastrophe could be averted and lost vision even restored using molecular medicine.

These are the words of Stuart Richer, OD, PhD, speaking at the 10th annual meeting and International Conference on Recent Trends in Therapeutic Advancement of Free Radical Science, in Chennai, India today.

For non-whites, geography plays key role in colon cancer screening

New research from UC Davis Cancer Center has found that whether a person gets screened for colon cancer often depends on where they live in addition to their race or ethnicity.

It has long been known that racial minorities have lower colorectal screening rates than whites, presumably because of differences in socioeconomic status, access to care and cultural issues. What hasn't been known, until now, is whether these differences also vary across geographic regions.

Race affects regional colorectal cancer screening disparities

Individuals from certain areas of the United States are more likely to get screened for colorectal cancer than those from other areas, particularly when comparing non-whites living in different parts of the country. That is the conclusion of a new study published early online in Cancer, a peer-reviewed journal of the American Cancer Society. Additional research is needed to better understand how colorectal cancer screening disparities develop in some regions and not in others.

Ginger is key ingredient in recipe for conserving stag beetles

Ginger is key ingredient in recipe for conserving stag beetles

Mayo researchers describe measles viral protein movement

ROCHESTER, Minn. -- Mayo Clinic researchers have shown that proteins on the surface of a cell twist a viral protein into position, allowing the virus to start infection and cause disease, all in a movement as graceful as a ballroom dance. The findings appear in the current online issue of Nature Structural & Molecular Biology.

Wildflower colors tell butterflies how to do their jobs

DURHAM, N.C. – The recipe for making one species into two requires time and some kind of separation, like being on different islands or something else that discourages gene flow between the two budding species.

In the case of common Texas wildflowers that share meadows and roadside ditches, color-coding apparently does the trick.

Quality of life measures in breast cancer clinical trials

Quality of life measures tend to be most useful for clinical decision-making in trials in which quality of life is the primary outcome, according to a recent study published online January 7 in The Journal of the National Cancer Institute.

Blame the 'chaperone'

A Jackson Laboratory research team led by Professor Patsy Nishina, Ph.D., has identified a mutation in a gene that's essential for correct protein-processing in cells. Defects in protein folding are associated with a variety of abnormalities and diseases.