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International COVID registry finds inequities in heart attack outcomes based on ethnicity
The latest, comprehensive data from The North American COVID-19 Myocardial Infarction (NACMI) Registry was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2021 Scientific Sessions. Results reveal in these series of STEMI activations during the COVID era, patients who tested positive for COVID-19 were less likely to receive diagnostic angiograms. Those with COVID-19 positive status had higher in-hospital mortality.
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Research could enable biotechnology advances: medicine, protective equipment, sensors
New Army-funded synthetic biology research manipulated micro-compartments in cells, potentially enabling bio-manufacturing advances for medicine, protective equipment and engineering applications.
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Virtual reality could help improve balance in older people
Researchers at CAMERA are investigating VR technology to help improve balance and prevent falls.
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New frontier for 3D printing developed state-of-the-art soft materials able to self-heal
The development of these materials may now be easier, and cheaper, thanks to the use of 3D printing: the researchers in the MP4MNT (Materials and Processing for Micro and Nanotechnologies) team of the Department of Applied Science and Technology of the Politecnico di Torino, coordinated by Professor Fabrizio Pirri, have demonstrated, for the first time, the possibility of manufacturing hydrogels with complex architectures capable of self-healing following a laceration, thanks to 3D printing activated by light.
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Processed diets might promote chronic infections that can lead to disorders such as diabetes
Processed diets, which are low in fiber, may initially reduce the incidence of foodborne infectious diseases such as E. coli infections, but might also increase the incidence of diseases characterized by low-grade chronic infection and inflammation such as diabetes, according to researchers in the Institute for Biomedical Sciences at Georgia State University.
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Using nanobodies to block a tick-borne bacterial infection
Tiny molecules called nanobodies, which can be designed to mimic antibody structures and functions, may be the key to blocking a tick-borne bacterial infection that remains out of reach of almost all antibiotics, new research suggests.
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How acidic are atoms?
How acidic is a surface? Up until now, only average values could be determined. But in order to understand the chemical behavior of a surface, it is important to know how individual atoms in the surface might react. A new microscopy technique developed in Vienna can now answer this question.
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Cancer-linked mutation accelerates growth of abnormal stroke-causing brain blood vessels
Researchers have discovered an explanation for why cerebral cavernous malformations (CCMs)--clusters of dilated blood vessels in the brain--can suddenly grow to cause seizures or stroke. Specifically, they found that a specific, acquired mutation in a cancer-causing gene (PIK3CA) could exacerbate existing CCMs in the brain. Furthermore, repurposing an already existing anticancer drug showed promise in mouse models of CCMs in improving brain-vascular health and preventing bleeding into the brain tissue.
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Proposal of new universal nomenclature for oxytocin and vasotocin genes
Oxytocin and arginine vasopressin are two hormones in the endocrine system that can act as neurotransmitters and regulate -in vertebrates and invertebrates- a wide range of biological functions, such as bonding formation, breastfeeding, birth or arterial pressure. Biochemists in the pregenomic era, named these genes differently in different species, due to small protein coding differences.
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Scientists see chemical short-range order in medium-entropy alloy
Chinese scientists have made direct observations in face-centered cubic VCoNi (medium)-entropy alloys (MEA) and for the first time proposed a convincing identification of subnanoscale chemical short-range order (CSRO). This achievement undisputedly resolves the pressing question of if, what and why CSRO exists, and how to explicitly identify CSRO.
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Study examines racial inequity in suicide prediction models
Models that can successfully predict suicides in a general population sample can perform poorly in some racial or ethnic groups, according to a study by Kaiser Permanente researchers published April 28 in JAMA Psychiatry.
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Major advance enables study of genetic mutations in any tissue
For the first time, scientists are able to study changes in the DNA of any human tissue, following the resolution of long-standing technical challenges by scientists at the Wellcome Sanger Institute. The new method, called nanorate sequencing (NanoSeq), makes it possible to study how genetic changes occur in human tissues with unprecedented accuracy.
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The Vertebrate Genomes Project introduces a new era of genome sequencing
With the publication of 16 high-quality reference genomes from across vertebrates, the project establishes standards for biodiversity genomics and reports discoveries in comparative biology, conservation, and health research.
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Brain's waste removal system may offer path to better outcomes in Alzheimer's therapy
Enhancing the brain's lymphatic system when administering immunotherapies may lead to better clinical outcomes for Alzheimer's disease patients, according to a new study in mice. Results published April 28 in Nature suggest that treatments such as the immunotherapies BAN2401 or aducanumab might be more effective when the brain's lymphatic system can better drain the amyloid-beta protein that accumulates in the brains of those living with Alzheimer's.
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Examining association between gender-affirming surgeries, mental health outcomes
What The Study Did: The association between undergoing gender-affirming surgery and mental health outcomes was looked at in this study.
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Racial/ethnic disparities of suicide prediction models after mental health visits
What The Study Did: Researchers evaluated racial/ethnic differences in the performance of statistical models that use health record data to predict the risk of suicide after an outpatient mental health visit.
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Trends in US internal medicine residency, fellowship applications during COVID-19 pandemic
What The Study Did: The number of applicants and number of applications submitted per applicant to internal medicine residency and subspecialty fellowships for 2021 during the COVID-19 pandemic were compared with five prior application cycles in this study.
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Assessment of length, readability of informed consent documents for COVID-19 vaccine trials
What The Study Did: Length, readability and complexity of informed consent documents for the COVID-19 vaccine phase III randomized clinical trials were assessed in this quality improvement study.
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Is forest harvesting increasing in Europe?
Is forest harvesting increasing in Europe? Yes, but not as much as reported last July in a controversial study published in Nature.Forest harvest has increased by just 6% in recent years, not 69% as reported by the European Commission's Joint Research Centre. The errors are due to satellite sensitivity and natural disturbances according to a response paper authored by 30 scientists from 13 European countries.
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Draining brain's debris enhances Alzheimer's therapies in mice
Researchers at Washington University School of Medicine in St. Louis have found that improving the function of the brain's drainage network, known as the meningeal lymphatics, can make certain experimental Alzheimer's therapies more effective in mice.
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