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Surprising findings can help improve organoid cultures, explain role of GSK3-beta in brain development

South Korea's Ulsan National Institute of Science and Technology (UNIST) has proposed a satellite-aided drought monitoring method that can adequately represent the complex drought conditions into a single integrated drought index.

A stem cell gene therapy developed by a team of researchers from UCLA and Great Ormond Street Hospital in London has successfully treated 48 of 50 children born with ADA-SCID, a rare and deadly inherited disorder that leaves them without an immune system.

An international team of researchers at Great Ormond Street Hospital (GOSH), and University of California, Los Angeles (UCLA) have developed a gene therapy that successfully treated 48 out of 50 children with a form of severe combined immunodeficiency that leaves them without an immune system.

Scientists at the he Centro Nacional de Investigaciones Cardiovasculares Centro de Biología Molecular Severo Ochoa (CBM-CSIC-UAM have shown that elevated activity of proteins regulated by nitric oxide (NO) causes the aortic disease seen in Marfan Syndrome patients.

A novel technique for studying vortices in quantum fluids has been developed by physicists writing in Nature Communications. Turbulence in quantum systems, for example in superfluid helium 4, takes place on microscopic scales, and so far scientists have not had tools with sufficient precision to probe eddies this small. But now the Lancaster team, working at temperature of a few thousandths of a degree above absolute zero, has harnessed nanoscience to allow the detection of single quantum vortices.

The brain alters our sense of time to synchronize our joint perception of sound and vision. A new study finds that this recalibration depends on brain signals constantly adapting to our environment to sample, order and associate competing sensory inputs together.

Researchers at the University of Bristol have discovered how microbes responsible for human African sleeping sickness produce sex cells.

Scientists have developed a novel genetic sensor called a "CopyCatcher," which capitalizes on CRISPR-based gene drive technology, to detect instances in which a genetic element is copied precisely from one chromosome to another throughout cells in the body of a fruit fly. Next-generation CopyCatcher systems have the potential to measure how often such perfect copying might take place in different cells of the human body.

Very thin layers of organic stabiliser residue in metal nanoparticle (MNP) inks are behind a loss of conductivity in 3D printed materials and electronic devices, according to the findings of a new study by the University of Nottingham and NPL (National Physical Laboratory).

A team of researchers from the Max Planck Institute for Chemical Ecology in Jena, Germany, demonstrates how the horseradish flea beetle regulates the accumulation of mustard oil glucosides in its body. The beetles have special transporters in the excretory system that prevent the excretion of mustard oil glucosides. This mechanism enables the insect to accumulate high amounts of the plant toxins in its body, which it uses for its own defense.

Susceptibility of their microbial partners to the herbicide may be an underestimated weak spot of insects that could add to their decline.

A team has come up with a way to solve two longstanding puzzles: the ages of individual fluid-bearing diamonds, and the chemistry of their parent material. The research has allowed them to sketch out geologic events going back more than a billion years--a potential breakthrough not only in the study of diamonds, but of planetary evolution.

The first comprehensive comparison of 'degrowth' scenarios with established pathways to limit climate change highlights the risk of over-reliance on technological innovation to support continued global growth - which is assumed in established global climate modelling. Findings include: Technologically less risky 'degrowth' limits global warming to 1.5C while global GDP declines by 0.5% annually; a maximum 2C warming can be achieved with 0% GDP growth using available technology (i.e. in line with technological trends).

Targeting a heat production 'brake' on fat tissues may be a safer way to treat obesity than current medication.

MIT researchers have generated what they describe as the most complete gene annotation of the SARS-CoV-2 genome. In their study, they confirmed several protein-coding genes and found that a few others that had been suggested as genes do not code for any proteins.

Researchers at Chalmers University of Technology, Sweden, have developed a new material that prevents infections in wounds - a specially designed hydrogel, that works against all types of bacteria, including antibiotic-resistant ones. The new material offers great hope for combating a growing global problem.

Aqueducts are very impressive examples of the art of construction in the Roman Empire. Even today, they still provide us with new insights into aesthetic, practical, and technical aspects of construction and use. Scientists investigated the longest aqueduct of the time, the 426-kilometer-long Aqueduct of Valens supplying Constantinople, and revealed new insights into how this structure was maintained back in time.

About 42% of rural school districts in the U.S. offered fully in-person instruction as of February, compared with only 17% for urban districts, according to a new RAND Corporation survey of school district leaders. The opposite pattern held for fully remote learning: 29% of urban districts offered fully remote instruction compared with 10% of rural districts and 18% of suburban districts.

A new paper in the Journal of the European Economic Association indicates that distrust generated by a 2011 CIA-led vaccination campaign ruse designed to catch Osama Bin Laden resulted in a significant vaccination rate decline in Pakistan.