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A protein modification of MECP2 can convey neuroprotection under inflammation

Eurekalert - May 19 2021 - 00:05
Researchers at the University of Eastern Finland have found a potential neuroprotective effect of a protein modification that could be a therapeutic target in early Alzheimer's disease. The new study investigated the role of MECP2, a regulator of gene expression, in Alzheimer's disease related processes in brain cells.
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Why bipolar patients don't take their meds

Eurekalert - May 19 2021 - 00:05
New research shows that people with bipolar disorder may not take their medication because of side effects, fear of addiction and a preference for alternative treatment.Nearly half of people with bipolar disorder do not take their medication as prescribed leading to relapse, hospitalisation, and increased risk of suicide.The new study reveals six key factors that stop people taking their medication as prescribed.
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Parental consumption shapes how teens think about and use cannabis

Eurekalert - May 19 2021 - 00:05
Turns out the old adage, "monkey see, monkey do," does ring true -- even when it comes to cannabis use. However, when cannabis use involves youth it's see, think, then do, says a team of UBC Okanagan researchers.The team found that kids who grow up in homes where parents consume cannabis will more than likely use it themselves.
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Cancer prevention and early detection continues to be suboptimal in the United States

Eurekalert - May 19 2021 - 00:05
Cancer prevention and early detection measures show mixed progress, and substantial racial/ethnic, socioeconomic, and geographic disparities continue to exist according to the recent American Cancer Society (ACS) article on cancer prevention and early detection efforts in the United States in 2018 and 2019.
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World met target for protected area coverage on land, but quality must improve

Eurekalert - May 19 2021 - 00:05
Major progress has been made towards a global target on protected and conserved area coverage set in 2010, but commitments on the quality of these areas have fallen far short, according to a new report from the UN and IUCN.
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VOYAGE phase 3: Dupilumab significantly reduced asthma exacerbations in children age 6-11

Eurekalert - May 19 2021 - 00:05
Results from the VOYAGE study of dupilumab (Dupixent) showed that the monoclonal antibody significantly reduced exacerbations in children ages 6-11 with uncontrolled moderate-to-severe asthma, compared to placebo, according to research presented at the ATS 2021 International Conference. VOYAGE (NCT02948959) is a recently completed randomized, placebo-controlled double-blind multicenter phase 3 clinical trial, that took place in a number of countries.
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Tezepelumab significantly reduced asthma exacerbations: Phase 3 NAVIGATOR trial

Eurekalert - May 19 2021 - 00:05
Results from the NAVIGATOR study of tezepelumab showed that the new biologic therapy significantly reduced exacerbations requiring hospital stays and emergency department (ED) visits for adults and adolescents with severe, uncontrolled asthma, according to research presented at the ATS 2021 International Conference. NAVIGATOR (NCT03347279) is a recently completed randomized, placebo-controlled double-blind multicenter phase 3 clinical trial.
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Tumor marker may help overcome endocrine treatment-resistant breast cancer

Eurekalert - May 19 2021 - 00:05
A study led by scientists at Sanford Burnham Prebys Medical Discovery Institute has identified a tumor marker that may be used to predict which breast cancer patients will experience resistance to endocrine therapy. The research offers a new approach to selecting patients for therapy that targets HER2, a protein that promotes the growth of cancer cells, to help avoid disease relapse or progression of endocrine-sensitive disease.
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Plant consumers play unexpectedly large role in the evolution of seedling success

Eurekalert - May 19 2021 - 00:05
Scientists have found that herbivores have a lot to say about plant evolution and determining the success of seedlings. The influence of birds, rabbits, mice and other herbivores likely counteracts early plant emergence due to climate change, the researchers found.
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We've got the dirt on soil protists

Eurekalert - May 19 2021 - 00:05
Among the large cast of microbiome players, bacteria have been hogging the spotlight. But the single-celled organisms known as protists are finally getting the starring role they deserve.
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Study led by NTU Singapore finds that microbes work as a network in causing lung infection

Eurekalert - May 19 2021 - 00:05
Traditionally, an infection is thought to happen when microbes enter and multiply in the body, and its severity is associated with how prevalent the microbes are in the body. Now, an international research team led by NTU Singapore is proposing that microbes in the body exist as a network, and that an infection's severity could be a result of 'negative interactions' between these microbes - when the microbes compete rather than cooperate with one another.
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Same nerve cell -- Different influence on food intake

Eurekalert - May 19 2021 - 00:05
Researchers reveal the diversity of our neurons.
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Children's sleep and adenotonsillectomy

Eurekalert - May 19 2021 - 00:05
While a pint-sized snorer may seem adorable, studies shows that children with sleep disordered breathing are likely to show aggressive and hyperactive behaviours during the day. The recommended treatment is an adenotonsillectomy - not only to fix the snore, but also the behaviour - yet new research from the University of South Australia, while the surgery can cure a child's snoring it doesn't change their behaviour, despite common misconceptions by parents and doctors alike.
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'No level of smoke exposure is safe'

Eurekalert - May 19 2021 - 00:05
This is the first evidence that secondhand smoke during pregnancy correlates with changes in disease-related gene regulation in babies. These findings support the idea that many adult diseases have their origins in environmental exposures, such as stress, poor nutrition, pollution or tobacco smoke, during early development.
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Scientists take a bite out of solar efficiency challenge with sandwich model

Eurekalert - May 19 2021 - 00:05
Research has revealed the structure of 2D perovskite thin films resembles a sandwich containing layers beneficial for generating electricity more efficiently in photovoltaics.
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Wireless and battery-free spintronic energy harvester

Eurekalert - May 19 2021 - 00:05
Researchers at the National University of Singapore (NUS) and Tohoku University have demonstrated that an array of electrically connected spintronic devices can harvest a 2.4 GHz wireless signal, which can be used to power and charge small electronic devices and sensors.
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New insights into androgen's action could boost battle against prostate cancer

Eurekalert - May 19 2021 - 00:05
Researchers have unveiled important new insights into how hormones known as androgens act on our cells - and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.
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New report indicates annual economic impact of human genetics/genomics

Eurekalert - May 19 2021 - 00:05
A new report issued by the American Society of Human Genetics indicates that human genetics and genomics grew over $200 billion since 2010, and has supported 850,000 U.S. jobs.
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An illuminating possibility for stroke treatment: Nano-photosynthesis

Eurekalert - May 19 2021 - 00:05
Blocked blood vessels in the brains of stroke patients prevent oxygen-rich blood from getting to cells, causing severe damage. Plants and some microbes produce oxygen through photosynthesis. What if there was a way to make photosynthesis happen in the brains of patients? Now, researchers reporting in ACS' Nano Letters have done just that in cells and in mice, using blue-green algae and special nanoparticles, in a proof-of-concept demonstration.
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New, biological, and safer soaps

Eurekalert - May 19 2021 - 00:05
An international research team led by Professor Charles Gauthier from the Institut national de la recherche scientifique (INRS) has discovered a new molecule with potential to revolutionize the biosurfactant market.
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