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Bile acids trigger satiety in the brain
EPFL scientists have discovered a new role for bile acids: they curb appetite by entering the brain. Their findings, which were recently published in Nature Metabolism, provide new insights into the signals and mechanisms by which satiety is controlled and may have implications for treating obesity.
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Decolonising ecology? How to adopt practices that make science more equitable
Knowledge systems outside of those sanctioned by Western universities have often been marginalised or simply not engaged with in many science disciplines, but there are multiple examples where Western scientists have claimed discoveries for knowledge that resident experts already knew and shared. According to a new paper there are five interventions to build a more anti-oppressive and decolonial ecology.
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Endangered wallaby population bounces back after ferals fenced out
UNSW scientists have used a new conservation strategy to give the bridled nailtail wallaby a head start in life.
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New insight into when CAR T is effective against childhood leukaemia
Scientists and clinicians at UCL and Great Ormond Street Hospital (GOSH) studying the effectiveness of CAR T-cell therapies in children with leukaemia, have discovered a small sub-set of T-cells that are likely to play a key role in whether the treatment is successful.
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How "paralyzed" immune cells can be reactivated against brain tumors
Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor. These results confirm that therapeutic vaccines or immunotherapies are more effective against brain tumors if active substances are simultaneously used to promote the suppressed immune system.
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Plant-microbe homeostasis: A delicate balancing act
Scientists from the Max Planck Institute for Plant Breeding Research in Cologne, and the University of North Carolina at Chapel Hill, have shown that the presence of both immune-suppressive and non-suppressive bacteria in the plant root microbiota is crucial to strike a balance between plant growth and plant defence, and maintain plant-microbe homeostasis.
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Researchers find greenland glacial meltwaters rich in mercury
New research shows that concentrations of the toxic element mercury in rivers and fjords connected to the Greenland Ice Sheet are comparable to rivers in industrial China, an unexpected finding that is raising questions about the effects of glacial melting in an area that is a major exporter of seafood.
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FSU researchers find Greenland glacial meltwaters rich in mercury
New research from Florida State University shows that concentrations of the toxic element mercury in rivers and fjords connected to the Greenland Ice Sheet are comparable to rivers in industrial China, an unexpected finding that is raising questions about the effects of glacial melting in an area that is a major exporter of seafood.
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Full-genome CRISPR screen reveals surprising ways neurons survive oxidative stress
When a single gene in a cell is turned on or off, its resulting presence or absence can affect the function and survival of the cell. In a new study appearing May 24 in Nature Neuroscience, UCSF researchers have successfully catalogued this effect in the human neuron by separately toggling each of the 20,000 genes in the human genome.
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Infertility poses major threat to biodiversity during climate change, study warns
A new study by University of Liverpool ecologists warns that heat-induced male infertility will see some species succumb to the effects of climate change earlier than thought. Currently, scientists are trying to predict where species will be lost due to climate change so they can plan effective conservation strategies. However, research on temperature tolerance has generally focused on the temperatures that are lethal to organisms, rather than those at which organisms can no longer breed.
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Babies with seizures may be overmedicated
Continuing antizeisure treatment after a baby's neonatal seizures stop may not be necessary, new study suggests.
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How tendons become stiffer and stronger
Researchers from ETH Zurich and the University of Zurich deciphered the cellular mechanisms through which tendons can adapt to mechanical stresses. People who carry a certain variant of a gene that is key to this mechanism show improved jumping performance.
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Cannabis-related exposures reported to US poison centers
What The Study Did: Researchers examined changes in reports to poison control centers from 2017 to 2019 of exposures to manufactured cannabis products and plant materials.
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Effectiveness of tocilizumab in patients hospitalized with COVID-19
What The Study Did: This follow-up study of a randomized clinical trial examines the association between survival and C-reactive protein levels in patients hospitalized with COVID-19 who were treated with tocilizumab.
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Socioeconomic, racial inequities in breast cancer screening during pandemic in Washington state
What The Study Did: Researchers used clinical data to examine differences in breast cancer screenings before and during the COVID-19 pandemic overall and among sociodemographic groups. Data included completed screening mammograms within a large statewide nonprofit community health care system from April 2018 through December 2020.
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Study reveals inequities in breast cancer screening during COVID-19 pandemic
Breast cancer screening took a sizeable hit during the COVID-19 pandemic, suggests new research that showed that the number of screening mammograms completed in a large group of women living in Washington State plummeted by nearly half. Published today in JAMA Network Open, the study found the steepest drop-offs among women of color and those living in rural communities.
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Milky Way not unusual, astronomers find
The first detailed cross-section of a galaxy broadly similar to the Milky Way, published today, reveals that our galaxy evolved gradually, instead of being the result of a violent mash-up. The finding throws the origin story of our home into doubt.
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Researchers identify the causes of the extreme drought that affected the Pantanal
The study shows that the 2019-20 drought resulted from a natural meteorological phenomenon similar to the one that caused the 2014-16 critical water shortage in São Paulo state, Southeast Brazil.
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Helping adults navigate the decision to move back in with parents
A recent study offers insight into how adults can navigate the often awkward experience of moving back in with their parents.
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Young teens should only use recreational internet and video games one hour daily
Middle-school aged children who use the internet, social media or video games recreationally for more than an hour each day during the school week have significantly lower grades and test scores, according to a study from the Center for Gambling Studies at Rutgers University-New Brunswick.
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