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Mice exposed to the opioid oxycodone before birth experience permanent changes in behavior and gene expression. The new research published in eNeuro highlights a need to develop safer types of painkillers for pregnant women.

Researchers have identified a rare class of genetic differences transmitted from parents without autism to their affected children with autism and determined that they are most prominent in "multiplex" families with more than one family member on the spectrum. These findings are reported in Recent ultra-rare inherited variants implicate new autism candidate risk genes, a new study published in Nature Genetics.

An international team of researchers from the Max Planck Institute for Plant Breeding Research and the University of Åarhus in Denmark have discovered that bacteria from the plant microbiota are adapted to their host species. In a newly published study, they show how root-associated bacteria have a competitive advantage when colonizing their native host, which allows them to invade an already established microbiota.

A new study reports that among individuals who had an allergic reaction to their first mRNA COVID-19 vaccine dose, all who went on to receive a second dose tolerated it. Even some who experienced anaphylaxis following the first dose tolerated the second dose.

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.

Lonely, older adults are nearly twice as likely to use opioids to ease pain and two-and-a-half times more likely to use sedatives and anti-anxiety medications, putting themselves at risk for drug dependency, impaired attention, falls and other accidents, and further cognitive impairment, according to a study by researchers at UC San Francisco.

What The Study Did: Survey data were used to investigate the relationship between loneliness and high-risk medication use in adults older than age 65.

What The Study Did: The association between Medicare eligibility at age 65 and changes in racial and ethnic disparities in access to care and self-reported health was evaluated in this study.

What The Study Did: Researchers examined the safety of the second dose of the Pfizer-BioNTech or Moderna COVID-19 vaccines in patients who experienced an allergic reaction to the first dose.

The visual cortex stores and remembers individual images, but when they are grouped into a sequence, mice can't recognize that without guidance from the hippocampus, according to a new study by neuroscientists at MIT's Picower Institute for Learning and Memory.

Improving air quality may improve cognitive function and reduce dementia risk, according to several studies reported today at the Alzheimer's Association International Conference® (AAIC®) 2021 in Denver, Colorado, and virtually.

There is an urgent need to develop and implement effective screening, diagnosis and treatment strategies for patients with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH), common liver conditions with a rising burden in the U.S. and globally. This is particularly important for the most at-risk patients, those with diabetes and obesity.

People who trust science are more likely to believe and disseminate false claims containing scientific references than people who do not trust science, a study finds. Reminding people of the value of critical evaluation reduces belief in false claims, but reminding them of the value of trusting science does not.

Scientists around the world are collaborating on a project that is changing the way they trace the evolutionary history of flowering plants. By using new technology allowing them to rapidly retrieve and compare DNA sequences from among any of the 300,000 species of flowering plants, scientists are unraveling the 140-million-year history of the largest group of land plants on Earth and providing a framework to protect vulnerable species and populations into the future.

A genetic analysis of fruit in the mandarin family has unraveled a complex journey from the mountainous region of southern China to the markets of Okinawa, says researchers from the Okinawa Institute of Science and Technology Graduate University.

Two drugs commonly used to treat high blood pressure are equally effective as single-drug therapies, but one is slightly safer, a new study has found.

Historically marginalized racial and ethnic groups and Indigenous peoples have significant cardiovascular health inequities, and these groups are underrepresented in genetic and genomic research.Almost 80% of participants in genomic research are of European ancestry, yet this group makes up just 16% of the global population.Heart-disease risk calculations and information about how different populations respond to treatment with medicines based on genetic studies are less accurate when used to assess risk for historically underrepresented or Indigenous peoples.

In an analysis of almost 3 million patients taking a single high blood pressure medication for the first time, angiotensin receptor blockers (ARBs) were as good as angiotensin-converting enzyme (ACE) inhibitors at preventing cardiovascular events linked to hypertension, including heart attack, stroke and heart failure.51 possible side effects and safety concerns were examined: The patients taking ARBs were found to be significantly less likely to develop tissue swelling, cough, pancreas inflammation and bleeding in the digestive tract.

Even in the absence of bark beetle outbreaks and wildfire, trees in Colorado subalpine forests are dying at increasing rates from warmer and drier summer conditions, found recent University of Colorado Boulder research.

Soft materials, like skin, behave differently than hard materials when punctured. They provide an unstable resistance that is more difficult to describe and hence predict. Researchers at the University of British Columbia have answered the previously unsolved question of how the mechanics of piercing works on soft materials by studying solutions from the natural world, and have created a mechanical theory that finally predicts the critical force necessary for needle insertion.