Feed aggregator
Shedding light on the dark side of firm lobbying
A firm's focus on customers may be diminished when it lobbies. Firm focus can be reoriented to customers, but doing so requires intentional, marketing-focused efforts.
Categories: Content
Oncotarget: Fgr and Numb in retinoic differentiation and G0 arrest of non-APL AML cells
In sum the Oncotarget data support a paradigm where signaling molecules bound to a Numb scaffold in a signalsome are activated by RA-induced Fgr expression
Categories: Content
Making negative opinions agreeable: Study finds social sharing happens in terms of support
Despite how toxic the social media sandbox can get, people more often share attitudes that are framed in terms of support instead of opposition, according to new research.
Categories: Content
Sharks, lies, and videotape: Scientists document problems with shark week
A new analysis by scientists shows that Shark Week, now in its 33rd year on the Discovery Channel, is deeply flawed in ways that undermine its goals, potentially harming both sharks and shark scientists. To document just how pervasive these issues are, a team of researchers performed a content and discourse analysis of more than 200 Shark Week episodes.
Categories: Content
"Noisy" gene expression may help improve stem cell therapies
As reported in the journal Science, Leor Weinberger and his team at Gladstone Institutes have discovered a pathway they named discordant transcription through repair (DiThR, pronounced "dither"). The DiThR pathway appears to boost the noisiness of gene expression in stem cells and enhance their ability to differentiate.
Categories: Content
Martian global dust storm ended winter early in the south
A dust storm that engulfed Mars in 2018 destroyed a vortex of cold air around the planet's south pole and brought an early spring to the hemisphere. By contrast, the storm caused only minor distortions to the polar vortex in the northern hemisphere and no dramatic seasonal changes.
Categories: Content
New dietary treatment for epilepsy well tolerated and reduced seizures
The first clinical trial of a new dietary treatment for children and adults with severe forms of epilepsy, co-developed by UCL researchers and based on the ketogenic diet, has been successfully completed.
Categories: Content
Meet the Martian meteorite hunters
A team at the Natural History Museum (NHM), London is paving the way for future rovers to search for meteorites on Mars. The scientists are using the NHM's extensive meteorite collection to test the spectral instruments destined for the ExoMars rover Rosalind Franklin, and develop tools to identify meteorites on the surface of the red planet. The project is being presented today (23 July) at the virtual National Astronomy Meeting 2021.
Categories: Content
Studies find combination chemotherapy beneficial and cost-effective in sub-Saharan Africa
Researchers at the UNC Lineberger Comprehensive Cancer Center demonstrated in a clinical trial in Malawi that a five-drug combination chemotherapy provided curative benefit compared to current standard-of care-therapy in people diagnosed with lymphoma, and now they have determined this option is also cost-effective.
Categories: Content
Mayo Clinic research suggests women over 65 be offered hereditary cancer genetic testing
A new study by Fergus Couch, Ph.D., of Mayo Clinic Cancer Center, along with collaborators from the CARRIERS consortium, suggests that most women with breast cancer diagnosed over 65 should be offered hereditary cancer genetic testing. The study was published Thursday, July 22, in the Journal of Clinical Oncology.
Categories: Content
Advanced bladder cancers respond to immunotherapy regardless of gene mutation status
UNC Lineberger researchers and colleagues report a study has demonstrated that patients with advanced bladder cancers whose tumors have a mutated FGFR3 gene respond to immunotherapy in a manner that is similar to patients without that mutation. This discovery runs counter to previous research that suggested FGFR3-mutated bladder cancers should not be treated with immunotherapy.
Categories: Content
Doctoral student bridges gap between electronics and optics
According to the United Nations' telecommunications agency, 93% of the global population has access to a mobile-broadband network of some kind. With data becoming more readily available to consumers, there is also an appetite for more of it, and at faster speeds.
Categories: Content
New tests can detect tiny but toxic particles of coal ash in soil
Duke University scientists have developed tests sensitive enough to detect and measure microscopic particles of coal ash in soil, even at concentrations so low and sizes so small that other tests would likely miss them. The four new tests complement tests previously developed at Duke to detect coal ash contamination in water and larger particles of coal ash in soil.
Categories: Content
Perfecting collagen production in osteogenesis imperfecta
Mesenchymal stem cells are the origin for osteoblasts, but MSC transplantation has not resulted in long-term success as a treatment option for brittle bone disease. Hematopoietic stem cells usually give rise to blood cells and osteoclasts, but researchers hypothesized that they could give rise to osteoblasts too. By replacing osteoblasts, they offer a potential therapeutic opportunity that is not dependent on a specific mutation but simply on a mutation being present, which gives patients hope.
Categories: Content
Big data-derived tool facilitates closer monitoring of recovery from natural disasters
By analyzing peoples' visitation patterns to essential establishments like pharmacies, religious centers and grocery stores during Hurricane Harvey, researchers at Texas A&M University have developed a framework to assess the recovery of communities after natural disasters in near real time. They said the information gleaned from their analysis would help federal agencies allocate resources equitably among communities ailing from a disaster.
Categories: Content
'Good cholesterol' may protect liver
The body's so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury. This HDL protects the liver by blocking inflammatory signals produced by common gut bacteria.
Categories: Content
Early-life social connections influence gene expression, stress resilience
Having friends may not only be good for the health of your social life, but also for your actual health--if you're a hyena, that is. Strong social connections and greater maternal care early in life can influence molecular markers related to gene expression in DNA and future stress response, suggests a new University of Colorado Boulder study of spotted hyenas in the wild.
Categories: Content
Study: Young workers now value respect over 'fun' perks in the workplace
Millennials, often referred to as the "job-hopping generation," represent a group of young workers who once grabbed the national spotlight with their publicized demands for "fun" work perks, such as happy hours. However, researchers at the Novak Leadership Institute at the University of Missouri and Kansas State University discovered today's young workers -- ages 21-34 -- represent a life-stage shift toward placing more value on having respectful communication in the workplace over trendy work perks.
Categories: Content
Synlogic publishes papers in Nature journals demonstrating proof-of-mechanism and potential of synth
Synlogic, Inc. announced today the publication of two papers in the journals Nature Metabolism and Communications Biology.
Categories: Content
Cattle losing adaptations to environment, MU researchers find
In a new PLOS Genetics study, researchers have uncovered evidence showing that cattle are losing important environmental adaptations, losses the researchers attribute to a lack of genetic information available to farmers. After examining genetic material stretching back to the 1960s, they identified specific DNA variations associated with adaptations that could one day be used to create DNA tests for cattle -- tests that could tell farmers whether their cattle are suited for one environment or another.
Categories: Content