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Whether bacteria are resistant to antibiotics is often decided at the cell membrane. This is where antibiotics can be blocked on their way into the cell interior or catapulted from the inside to the outside. Macrocyclic peptides, a novel class of antibiotics, bioactive cytotoxins and inhibitors, shed light on how this transport process occurs at the membrane, how it is influenced and how it can be used to circumvent the resistance of a malignantly transformed cell.

A newfound biomolecule, consisting of RNA modified by sugars, could be present in all forms of life and might contribute to autoimmune disease.

In a study of low-income, urban youth in the U.S., researchers at Columbia University Mailman School of Public Health found that students exposed to Photovoice, an educational intervention, experienced greater improvements in STEM-capacity scores and environmental awareness scores compared to a group of youth who were not exposed to the activity. The results suggest that the Photovoice activities may be associated with improved learning outcomes.

The development of dementia, often from Alzheimer's disease, late in life is associated with abnormal blood levels of dozens of proteins up to five years earlier.

Machine learns to categorize pottery comparable to expert archaeologists, matches designs among thousands of broken pieces

A national study on childhood asthma led by Henry Ford Health System has found that family history, race and sex are associated in different ways with higher rates of asthma in children.

Greenhouse gases and aerosol pollution emitted by human activities are responsible for increases in the frequency, intensity and duration of droughts around the world, according to a new Nature Communications study by researchers at the University of California, Irvine.

Among patients with both heart failure and atrial fibrillation (AFib), treatment strategies focused on controlling the heart rhythm (using catheter ablation) and those focused on controlling the heart rate (using drugs and/or a pacemaker) showed no significant differences in terms of death from any cause or progression of heart failure, according to a study presented at the American College of Cardiology's 70th Annual Scientific Session.

Contamination risk of groundwater in karst regions is higher than previously believed

Supermassive black holes devour stellar material just like their more petite counterparts, an MIT study finds.

Top experts from Brigham and Women's Hospital presented outcomes from some of the most-anticipated clinical trials in cardiology at the virtual American College of Cardiology's 70th Annual Scientific Session. In four Late-Breaking Clinical Trial presentations, Brigham cardiologists shared their latest findings on strategies to prevent future cardiovascular events in at-risk patient populations, results of a randomized clinical trial of a statin drug among patients critically ill with COVID-19, and more.

As COVID-19 spread around the world, stock markets in individual countries took a major hit - yet stock markets in China where the disease first struck avoided significant falls - researchers at Lero, the Science Foundation Ireland Research Centre for Software found.

Alcohol appears to have an immediate--or near-immediate--effect on heart rhythm, significantly increasing the chance that an episode of atrial fibrillation (AFib) will occur, according to new data presented at the American College of Cardiology's 70th Annual Scientific Session.

At night in southern Africa, primates called bushbabies emit "spooky" vocalizations that sound a like crying children. What may be even spookier is the possible future facing these adorable creatures.

The ocean is a big place with many deep, dark mysteries. Humans have mapped no more than 20% of the sea, and explored less. Even the kelp forests of Southern California -- among the best studied patches of ocean on the planet -- hide species not yet described by science.

A subgroup of patients who experienced an out-of-hospital cardiac arrest (OHCA) that did not respond to standard advanced cardiac life support (ACLS), were immediately transported to a cardiac care center, and placed on a device similar to a heart-lung bypass machine were more likely to have survived with good brain function six months later than similar patients who received standard care at the site where the OHCA occurred.

Patients with chronic kidney disease and Type 2 diabetes who took the experimental drug finerenone were about 30% less likely to develop the heart rhythm disorder atrial fibrillation (AFib) than those taking a placebo, according to data presented at the American College of Cardiology's 70th Annual Scientific Session.

In patients receiving therapeutic hypothermia after suffering out-of-hospital cardiac arrest, those who were cooled below 31 degrees Celsius (about 88 degrees Fahrenheit) for 24 hours showed no difference in terms of death or poor neurological outcomes at six months compared with patients receiving guideline-recommended cooling of 34 C (about 93 F). These findings are part of a study presented at the American College of Cardiology's 70th Annual Scientific Session.

Researchers at the University of California, Davis, have found a link between traffic-related air pollution and an increased risk for age-related dementia, including Alzheimer's disease. Their study, based on rodent models, corroborates previous epidemiological evidence showing this association.

Researchers have discovered a long noncoding RNA whose function was previously unknown that turns out to play an important role in promoting the body's immune response against cancer and holds promise for enhancing the efficacy of anti-cancer immunotherapy.