Body

A new study conducted in a cancer center in a state with legalized medicinal and recreational marijuana found that approximately one-quarter of surveyed patients used marijuana in the past year, mostly for physical and psychological symptoms. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study also revealed that legalization increased the likelihood for use among patients.

Scientists at British American Tobacco (BAT) have created the most comprehensive database of scientific test results, to date, for an e-cigarette (Vype ePen). The results of the studies provide evidence that suggests Vype ePen has the potential to be substantially reduced risk compared to traditional cigarettes.

In a study, researchers at the University of São Paulo's Ribeirão Preto School of Medicine (FMRP-USP), in Brazil, finds that the more frequent the migraine attacks, the more severe will be the so-called temporomandibular disorder, or TMD. The temporomandibular joint acts like a sliding hinge connecting the jawbone to the skull, therefore the disorder's symptoms includes difficulty chewing and joint tension.

A new test that combines the effects of more than two dozen genetic variants, most associated by themselves with only a small risk of Alzheimer's disease, does a better job of predicting which cognitively normal older adults will go on to develop Alzheimer's dementia than testing only for the well-known genetic variant APOE E4, a scientific team led by researchers at UC San Francisco and UC San Diego has found.

CHICAGO--The nation's emergency departments had low rates of complying with recommended HIV and syphilis screening for at-risk adolescents, though larger hospitals were more likely to provide such evidence-based care, according to a study presented during the 2017 American Academy of Pediatrics (AAP) national conference.

A research led by Jordi Surrallés, professor of the Department of Genetics and Microbiology at the Universitat Autònoma de Barcelona, director of the Genetics Unit at the Hospital de la Santa Creu i Sant Pau and lead researcher at the Centre for Biomedical Network Research on Rare Diseases (CIBERER), has identified a new genetic syndrome caused by mutations in both copies of the FANCM gene, also known as biallelic mutations.

Tracing the history of individual cells in the developing organism can reveal functional differences among seemingly uniform cells. This knowledge is important for defining the characteristics of highly regenerative cells in order to target them for cellular therapies, as well as to prevent the formation of unfit cells, which compromise the overall health of the organism. The study introduced here presents a new method for tracing the history of β-cells, which perform the essential function of secreting insulin in response to glucose.

Whether or not we consciously perceive the stimuli projected onto our retina is decided in our brain. A recent study by the University of Bonn shows how some signals dissipate along the processing path to conscious perception. This process begins at rather late stages of signal processing. By contrast, in earlier stages there is hardly any difference in the reaction of neurons to conscious and unconscious stimuli. The paper is published in Current Biology.

Bottom Line: A pre-existing diagnosis of dementia was associated with increased risk of death for older patients with advanced colon cancer; however, some of the effects of dementia on survival could be mediated by receipt of chemotherapy.

Journal in Which the Study was Published: Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

Author: Yingjia Chen, PhD, a postdoctoral fellow in the Memory and Aging Center in the Department of Neurology at University of California, San Francisco.

Highlights

From 2006 to 2010, almost two thirds of US dialysis patients received at least one opioid prescription every year and >20% received chronic prescriptions.

More than 25% of dialysis patients using opioids received doses exceeding recommendations

Use of opioid medications was linked with higher risks of early death, discontinuation of dialysis, and the need for hospitalization in dialysis patients.

In 2016, the Centers for Disease Control and Prevention released a clinical guideline for prescribing opioids for chronic pain.