BACKGROUND
In the Alzheimer's brain, hard plaques accumulate between the nerve cells while twisted fibers grow inside the nerve cells. The plaques arise from protein fragments called beta amlyoid, and the fibers form from a protein called tau. Doctors rely on brain scans to detect amyloid and tau and provide early intervention and treatment to potentially slow or reverse disease progression.
FINDINGS
How the imaging agents work that scan the Alzheimer's brain is unknown. A new UCLA study reveals the physical mechanisms that allow chemical agents to bind to and detect amyloid beta plaques and tau tangles in the brain. The discovery will speed the development of new imaging agents, enabling quicker diagnosis and earlier treatment.
Source: University of California - Los Angeles Health Sciences