Tech

Sipuleucel-T (trade name Provenge) has been approved since September 2014 for men with metastatic prostate cancer who have few or no symptoms and do not yet require chemotherapy. In the dossier assessment conducted by the German Institute for Quality and Efficiency in Health Care (IQWiG) in January 2015, no added benefit could be derived for sipuleucel-T.

When patients develop acute liver failure, severe complications arise rapidly after the first signs of liver disease, and patients' health can deteriorate rapidly. New research published in the American Journal of Transplantation indicates that emergency evaluations of living liver donors can be conducted safely to allow acute liver failure patients to undergo transplantation before their condition worsens.

A phase 3 trial of brentuximab vedotin (BV), the first new drug for Hodgkin lymphoma in over 30 years, shows that adults with hard-to-treat Hodgkin lymphoma given BV immediately after stem cell transplant survived without the disease progressing for twice as long as those given placebo (43 months vs 24 months).

The findings, published in The Lancet, are potentially practice changing for this young cancer population who have exhausted other treatment options and for whom prognosis is poor.

Without antibodies we would be at the mercy of pathogens or cancer cells. Therapeutic antibodies are used as passive vaccines, for cancer therapy or for controlling autoimmune diseases such as multiple sclerosis. According to "bccresearch.com" the global market for antibody drugs was worth nearly 70 billion USD in 2014 and should rise to 122 billion USD until 2019.

Using discarded electronic boards, the UPV/EHU researcher Andoni Salbidegoitia has, in collaboration with international researchers, developed a system for obtaining clean hydrogen that can be used as fuel. The researchers have already registered the patent of the process in Japan.

The Chemical Technologies for Environmental Sustainability (TQSA) Group of the Department of Chemical Engineering of the UPV/EHU's Faculty of Science and Technology is aiming to make use of discarded plastic as effectively as possible from the environmental as well as energy and economic point of view.

Winter storms dumped records amounts of snow on the East Coast and other regions of the country this February, leaving treacherous, icy sidewalks and roads in their wake. Now researchers from Canada are developing new methods to mass-produce a material that may help pedestrians get a better grip on slippery surfaces after such storms.

A Northwestern University-led study in the emerging field of nanocytology could one day help men make better decisions about whether or not to undergo aggressive prostate cancer treatments.

Technology developed by Northwestern University researchers may help solve that quandary by allowing physicians to identify which nascent cancers are likely to escalate into potentially life-threatening malignancies and which ones will remain "indolent," or non-aggressive.

While looking for life on planets beyond our own solar system, a group of international scientists has created a colorful catalog containing reflection signatures of Earth life forms that might be found on planet surfaces throughout the cosmic hinterlands. The new database and research, published in the March 16 Proceedings of the National Academy of Sciences, gives humans a better chance to learn if we are not alone.

Two-year data show a continued survival advantage for self-expanding transcatheter aortic valve replacement (TAVR) over standard surgery in high-risk patients with severe aortic stenosis, according to research presented at the American College of Cardiology's 64th Annual Scientific Session.

A means by which the removal of carbon dioxide (CO2) from coal-fired power plants might one day be done far more efficiently and at far lower costs than today has been discovered by a team of researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab). By appending a diamine molecule to the sponge-like solid materials known as metal-organic-frameworks (MOFs), the researchers were able to more than triple the CO2-scrubbing capacity of the MOFs, while significantly reducing parasitic energy.

Patients who received the new drug Bendavia before undergoing angioplasty or receiving a stent to clear blocked arteries after a heart attack showed no significant reduction in scarring as compared to patients given a placebo, according to a study presented at the American College of Cardiology's 64th Annual Scientific Session.

According to a meta-analysis published in BMC Family Practice, high dose zinc acetate lozenges may help shorten diverse symptoms associated with the common cold. The common cold is an infection caused by over a hundred viruses, and it is a major cause of days off school or work and visits to a doctor.

A flu vaccine given just under the surface of the skin that includes four strains of inactivated influenza could be more protective than a similar flu vaccine containing only three strains, Saint Louis University research found.

These findings, which appear in Vaccine, confirmed the expected results, said Geoffrey Gorse, M.D., professor of internal medicine in the division of infectious diseases at Saint Louis University and the study's lead author.

Light can be used to activate normal, non-genetically modified neurons through the use of targeted gold nanoparticles, report scientists from the University of Chicago and the University of Illinois at Chicago. The new technique, described in the journal Neuron on March 12, represents a significant technological advance with potential advantages over current optogenetic methods, including possible use in the development of therapeutics toward diseases such as macular degeneration.

Researchers from General Atomics and the U.S. Department of Energy's Princeton Plasma Physics Laboratory (PPPL) have made a major breakthrough in understanding how potentially damaging heat bursts inside a fusion reactor can be controlled. Scientists performed the experiments on the DIII-D National Fusion Facility, a tokamak operated by General Atomics in San Diego. The findings represent a key step in predicting how to control heat bursts in future fusion facilities including ITER, an international experiment under construction in France to demonstrate the feasibility of fusion energy.