Many disease-causing microbes carry pumps that expel antibiotics, making the bugs hard to kill with standard drugs.
Ironically, these same pumps could be the bugs' Achilles heel.
University of California, Berkeley, scientists have found that the molecular pumps in Listeria bacteria, and perhaps in other pathogens, also expel small signaling molecules that stimulate a strong immune response in the cells they infect. A robust immune response, involving mobilization of killer cells and a host of other defenses, is needed to kill bad microbes before they can do damage