Picture two charged particles in a vacuum. Thanks to laws of elementary electrostatics, we can easily calculate the force these particles exert upon one another, and therefore predict their movements.
Submerge those particles in a simple medium — say, water — and the calculation grows more complex. The charged particles' movements influence the water, which in turn may slow, speed, or otherwise alter the particles' paths. In this environment a prediction must also consider the water's reaction, or its dielectric response.