Culture

Study debunks myths about gender and math performance

MADISON — A major study of recent international data on school mathematics performance casts doubt on some common assumptions about gender and math achievement — in particular, the idea that girls and women have less ability due to a difference in biology.

"We tested some recently proposed hypotheses that try to explain a supposed gender gap in math performance and found they were not supported by the data," says Janet Mertz, senior author of the study and a professor of oncology at the University of Wisconsin-Madison.

Bone marrow and blood stem cell transplant survival rates equal, when donor is unrelated to patient

Patients who receive a blood stem cell transplant from a donor outside of their family to treat leukemia and other blood diseases are more likely to have graft failure but less likely to experience graft-versus-host disease, a condition caused by the donor cells attacking the recipient's body, if the transplanted blood cells come directly from a donor's bone marrow, rather than from blood stem cells circulating in the donor's bloodstream (PBSCs), according to new research.

Patient isolation associated with hospital delirium: Study

CHICAGO (December 12, 2011) -- A new study finds that patients who are moved into isolation during a hospital stay are nearly twice as likely to develop delirium, a potentially dangerous change in mental status that often affects hospital patients. Patients who began their stay in isolation were not at increased risk.

Exercise/memory research for Parkinson's

Baltimore, MD – December 12, 2011. Researchers from the University of Maryland School of Medicine and the Baltimore VA Medical Center have launched a study of exercise and computerized memory training to see if those activities may help people with Parkinson's disease prevent memory changes. The type of memory that will be examined is known as "executive function;" it allows people to take in information and use it in a new way.

Gene mutation signals a high risk of recurrence in some older acute-leukemia patients

COLUMBUS, Ohio – Older people with acute myeloid leukemia and normal looking chromosomes in their cancer cells have a higher risk of recurrence if they have mutations in a gene called ASXL1, according to a new study by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James).

Patient isolation associated with hospital delirium: study

CHICAGO (December 12, 2011) -- A new study finds that patients who are moved into isolation during a hospital stay are nearly twice as likely to develop delirium, a potentially dangerous change in mental status that often affects hospital patients. Patients who began their stay in isolation were not at increased risk.

Improved medication use could reduce severe asthma attacks

DETROIT – Researchers at Henry Ford Hospital have found that one-quarter of severe asthma attacks could be prevented if only patients consistently took their medication as prescribed.

Moreover, an asthma attack was only significantly reduced when patients used at least 75 percent of their prescribed dose, according to the study.

Patients often poorly take their medication based on the onset and degree of symptoms.

Planting improves heart rate, stress levels of mentally challenged adults

DAEGU, SOUTH KOREA—Participation in horticultural activities can improve confidence and social skills, cultivate a positive attitude, and rejuvenate the mind and body. Many studies have emphasized the effects of horticultural activities in relation to physical and psychological rehabilitation, but few have considered the influence of these types of activities on mentally challenged people's autonomic nervous system (ANS) and on the stress hormone cortisol.

Ruxolinitib better at reducing myelofibrosis symptoms, study shows

SAN DIEGO -- In a major advance in treatment, a multicenter study found that ruxolinitib did a better job than off-label chemotherapy drugs reducing the terrible symptoms associated with myelofibrosis, including pain, enlarged spleen, anemia, fever, chills, fatigue, and weight loss. The results were presented today at the annual meeting of the American Society of Hematology and Oncology in San Diego.

New scanning strategy could help develop heart disease treatments

Patients with life-threatening heart valve disease could be helped with alternative scanning techniques that provide greater insight into the condition.

Researchers from the University of Edinburgh used an imaging technique that could help predict which patients will need open heart surgery to replace their heart valves, and improve treatments to prevent the disease.

Studies examine novel treatment techniques for bleeding and clotting disorders

(SAN DIEGO, December 10, 2011) – Bleeding and clotting disorders affect a large number of patients annually and, while accurate diagnosis is important, timely and effective treatment for these disorders is key, as they have the potential to quickly become life-threatening. Research examining novel treatment techniques for bleeding and clotting disorders will be presented today at the 53rd Annual Meeting of the American Society of Hematology.

Emerging lymphoma and myeloma treatments focus on improving individual patient response

(SAN DIEGO, December 11, 2011) – Lymphoma and myeloma are both malignant diseases that arise from lymphocytes, a subset of blood cells, and commonly involve lymph nodes and the bone marrow. Although considerable progress has been made in the treatment of these diseases, they remain a significant challenge for patients and their hematologists. New research introducing unique treatment approaches and targets for lymphoma and myeloma will be presented today at the 53rd Annual Meeting of the American Society of Hematology.

Study favors as-needed treatment over maintenance therapy for patients with follicular lymphoma

(SAN DIEGO, December 11, 2011) – Asymptomatic patients diagnosed with nonbulky follicular lymphoma, a slow-growing type of non-Hodgkin lymphoma, have traditionally been watched for signs or symptoms of disease progression and then treated with a combination of rituximab and chemotherapy or rituximab alone for select cases.

Penn researchers repair immune system in leukemia patients following chemotherapy

(SAN DIEGO) –– A new treatment using leukemia patients' own infection-fighting cells appears to protect them from infections and cancer recurrence following treatment with fludarabine-based chemotherapy, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

Novel experimental agent is highly active in CLL patients, interim study shows

COLUMBUS, Ohio – An interim analysis of a phase Ib/II clinical trial indicates that a novel experimental agent for chronic lymphocytic leukemia (CLL) is highly active and well tolerated in patients who have relapsed and are resistant to other therapy. The agent, called PCI-32765, is the first drug designed to target Bruton's tyrosine kinase, a protein essential for CLL-cell survival and proliferation. CLL is the most common form of leukemia, with about 15,000 new cases annually in the U.S. About 4,400 Americans die of the disease each year.