Culture

Study shows the HPV vaccine Gardasil doesn't increase disease activity in SLE patients

Results of a Chinese study showed that the HPV vaccine did not have significant effects on the number of disease flares or antibody measures in patients with inactive SLE receiving stable doses of medications after administration, and therefore was determined safe to use to prevent HPV in this group of patients.

Inability to cry in patients with Sjogrens syndrome affect emotional and mental well-being

The results of a Dutch study of 300 patients demonstrated that 22% of patients with Sjögren's syndrome were classified as clinically 'alexithymic' (experiencing difficulty identifying and describing emotions) compared to 12% of healthy controls. Subsequent results of the study showed that higher levels of alexithymia were moderately correlated with worse mental wellbeing in both groups (Pearson's correlation* (r) ≥ 0.32, p< 0.001), showing that there is a proven link between the two.

Diabetes can be predicted 7 years before pregnancy with blood sugar and body weight

OAKLAND, Calif. — A woman's risk of developing diabetes during pregnancy can be identified up to seven years before she becomes pregnant based on routinely assessed measures of blood sugar and body weight, according to a Kaiser Permanente study published in the online issue of the American Journal of Obstetrics and Gynecology.

Large NIH funded rehabilitation study looks at getting stroke patients back on their feet

In the largest stroke rehabilitation study ever conducted in the United States, stroke patients who had physical therapy at home improved their ability to walk just as well as those who were treated in a training program that requires the use of a body-weight supported treadmill device followed by walking practice.

Economic recovery is stronger in states where people are more optimistic, says UM study

Coral Gables, Fla. – May 25, 2011 – Economic recessions are weaker, expansions are stronger, and economic recovery is faster in U.S. states where people are more optimistic says a new study from the University of Miami School of Business Administration. Further, the effects are stronger in states where people are older, less educated and less socially connected.

Many patients fail to properly take oral chemo, leading to complications

EAST LANSING, Mich. — As the use of oral chemotherapy continues to rise, researchers from Michigan State University have discovered many patients fail to properly take the cancer-fighting medication, a significant clinical problem that can result in complications and premature death.

That lack of adherence needs to be addressed by the health care community, said College of Nursing researcher Barbara Given, who led the study that is published in the May edition of Seminars in Oncology Nursing.

Most labor unions unlikely to follow decertification path of NFL players

CHAMPAIGN, Ill. — With legislation to diminish private- and public-sector collective bargaining rights already in the books in Wisconsin and Ohio, should more labor unions steal a page from the playbook of the NFL Players Association and decertify? Although there are parallels between the pros and regular Joes (and Janes), union decertification is not a viable strategy for ordinary workers to use when bargaining for better wages and working conditions, says a University of Illinois law and labor expert.

Medicare payment adjustments -- focus of new IOM report releasing June 1

The Medicare program adjusts its baseline payments to hospitals and individual health care practitioners based on regional variations in expenses beyond providers' control, such as rents, wages, and liability premiums. The goal is to ensure that payments are accurate and fair, but many providers and policymakers have expressed doubts about the accuracy of these adjustments. Geographic Adjustment in Medicare Payments, a new report from the Institute of Medicine, assesses the methodology and data sources used to calculate payment adjustments and recommends ways to improve their accuracy.

Dangerous side effect of common drug combination discovered by Stanford data mining

STANFORD, Calif. — A widely used combination of two common medications may cause unexpected increases in blood glucose levels, according to a study conducted at the Stanford University School of Medicine, Vanderbilt University and Harvard Medical School. Researchers were surprised at the finding because neither of the two drugs — one, an antidepressant marketed as Paxil, and the other, a cholesterol-lowering medication called Pravachol — has a similar effect alone.

Research says 9/11 produced permanent shift to Republican party among new young US voters

Research led by the University of Warwick's Centre for Competitive Advantage in the Global Economy has found that not only did the events of 9/11 produce an immediate shift in favour of the Republican party among new young US voters but that shift persisted into later years. The research shows that party strategists should focus on winning over voters when they are young.

Arrival of direct antiviral agent therapy for hepatitis C sparks debate of who to treat first

For many patients with the hepatitis C virus (HCV), direct antiviral agents (DAA) offer a potential cure for the disease. The Food and Drug Administration (FDA) has recently approved two new DAAs, telaprevir and boceprevir, and with that clinicians must now decide who should be the first to receive this treatment. Discussion of this timely topic is now available in the June issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

Pelvic widening continues throughout a person's lifetime, UNC study

CHAPEL HILL, N.C. – By the age of 20, most people have reached skeletal maturity and do not grow any taller. Until recently it was assumed that skeletal enlargement elsewhere in the body also stopped by age 20.

But a new study by researchers at the University of North Carolina at Chapel Hill has found evidence that, even though you're not getting taller anymore, the pelvis ("hipbones") does continue to widen as people advance in age from 20 years to 79 years.

Targeted adalimumab treatment can optimize long-term outcomes for patients with early RA

Data presented today at the EULAR 2011 Annual Congress demonstrated that initial treatment with adalimumab (Humira, ADA) plus methotrexate in early RA patients can provide high levels of disease control in many patients, and may also offer the opportunity to change future treatment options for some.

US study shows that tofacitinib is an efficacious treatment for active RA

Results of a Phase III study presented today at the EULAR 2011 Annual Congress show that at 6 months, 58.3 percent of patients who had previously not responded to treatment with DMARDs, achieved ACR20 response (a 20 percent improvement in symptoms) when treated with the novel oral Janus kinase inhibitor tofacitinib at 10mg BID compared to 31.2 percent in the placebo group. Significant improvements were also observed in the 5 mg BID dose.

Most adverse events were mild and no new safety signals were reported, according to study authors.

New tool aims to improve measurement of primary care depression outcomes

ANN ARBOR, Mich. — Primary care doctors have long been on the front lines of depression treatment. Depression is listed as a diagnosis for 1 in 10 office visits and primary care doctors prescribe more than half of all antidepressants.

Now doctors at the University of Michigan Health System have developed a new tool that may help family physicians better evaluate the extent to which a patient's depression has improved.