Brain

To pinpoint why depression messes with memory, researchers took a page from Sesame Street's book.

The show's popular game "One of these things is not like the others" helps young viewers learn to differentiate things that are similar – a process known as "pattern separation."

A new Brigham Young University study concludes that this same skill fades in adults in proportion to the severity of their symptoms of depression. The more depressed someone feels, the harder it is for them to distinguish similar experiences they've had.

When something we do produces a positive result, we actually perceive it differently than we would if that same action yielded a negative result. In particular, people feel a greater connection between voluntary actions and their outcomes if those outcomes are good than if they are bad. The discovery, reported on October 3 in Current Biology, a Cell Press publication, yields important insight into notions about personal responsibility.

Autophagy, a key cellular auto-cleaning mechanism, mediates the formation of amyloid beta plaques, one of the hallmarks of Alzheimer's disease. It might be a potential drug target for the treatment of the disease, concludes new research from the RIKEN Brain Science Institute in Japan. The study sheds light on the metabolism of amyloid beta, and its role in neurodegeneration and memory loss.

NEW YORK (October 3, 2013) -- Using powerful genetic sequencing technology, a team of investigators, led by researchers at the Icahn School of Medicine at Mount Sinai, scanned the genome of hundreds of individuals, and discovered those diagnosed with autism spectrum disorder (ASD) were more likely to have gene deletions than were people without the disorder. That means those individuals -- seven percent of the study group -- had one copy of one or more genes when they should have had two.

Why does hunger keep us awake and a full belly make us tired? Why do people with sleep disorders such as insomnia often binge eat late at night? What can sleep patterns tell us about obesity?

Sleep, hunger and metabolism are closely related, but scientists are still struggling to understand how they interact. Now, Brandeis University researchers have discovered a function in a molecule in fruit flies that may provide insight into the complicated relationship between sleep and food.

Tampa, FL (Oct. 3, 2013) -- University of South Florida researchers have suggested a new view of how stem cells may help repair the brain following trauma. In a series of preclinical experiments, they report that transplanted cells appear to build a "biobridge" that links an uninjured brain site where new neural stem cells are born with the damaged region of the brain.

Their findings were recently reported online in the peer-reviewed journal PLOS ONE.

Think of a frequently used noun or verb in our language. Try to count how many times you have uttered it in the last two hours. Now, do the same with the article "the". The language we speak is not only made of content words (nouns, verbs, adjectives, for instance) but also of lots of words that provide a support to them (articles, prepositions, etc.) that are used much more frequently than the first (function words, or functors).

Cold Spring Harbor, NY -- A multidisciplinary team led by a geneticist and psychiatrist from Cold Spring Harbor Laboratory's (CSHL) Stanley Institute for Cognitive Genomics today publish a paper providing a glimpse of both the tremendous power and the current limitations of what is sometimes called "precision medicine."

Every day we recognize friends, family, and co-workers from afar -- even before we can distinctly see a face. New research reveals that when facial features are difficult to make out, we readily use information about someone's body to identify them -- even when we don't know we're doing so.

Patients treated in intensive care units across the globe are entering their medical care with no evidence of cognitive impairment but oftentimes leaving with deficits similar to those seen in patients with traumatic brain injury (TBI) or mild Alzheimer's disease (AD) that persists for at least a year, according to a Vanderbilt study published today in the New England Journal of Medicine.

GRAND RAPIDS, Mich., October 2, 2013 – A recently published study by researchers from Spectrum Health and Henry Ford Hospital suggests that surgery may be an effective treatment for epilepsy in older patients, a finding that runs counter to conventional treatment methods.

Nocturnal animals need their noses to stay alive. Mice, among others, depend on their impressive olfactory powers to sniff out food or avoid danger in the dark.

A team of scientists led by Dr. Antoine Adamantidis, a researcher at the Douglas Mental Health University Institute and an assistant professor at McGill University, has released the findings from their latest study, which will appear in the October issue of the prestigious scientific journal Nature Neuroscience.(1)

Washington D.C., October 2, 2013 – A study published in the October 2013 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that approximately one in three teens with bipolar disorder developed substance abuse, for the first time, during 4 years of follow-up. The study also identified several risk factors that predicted who among these teens was most likely to develop substance abuse.

The song of songbirds is a learned, complex behavior and subject to strong selective forces. However, it is difficult to tease apart the influence of the genetic background and the environment on the expression of individual variation in song. Scientists from the Max Planck Institute for Ornithology in Seewiesen in collaboration with international researchers now compared song and brain structure of parents and offspring in zebra finches that have been raised either with their genetic or foster parents. They also varied the amount of food during breeding.