Brain

FDA approved immune-modulating drug unexpectedly benefits mice with fatal mitochondrial defect

The transplant anti-rejection drug rapamycin showed unexpected benefits in a mouse model of a fatal defect in the energy powerhouses of cells, the mitochondria. Children with the condition, Leigh syndrome, show progressive brain damage, muscle weakness, lack of coordination or muscle control, and weight loss, and usually succumb to respiratory failure.

Late afternoon and early evening caffeine can disrupt sleep at night

DARIEN, IL – A new study shows that caffeine consumption even six hours before bedtime can have significant, disruptive effects on sleep.

"Sleep specialists have always suspected that caffeine can disrupt sleep long after it is consumed," said American Academy of Sleep Medicine President M. Safwan Badr, MD. "This study provides objective evidence supporting the general recommendation that avoiding caffeine in the late afternoon and at night is beneficial for sleep."

Your brain 'sees' things even when you don't

The brain processes visual input to the level of understanding its meaning even if we never consciously perceive that input, according to new research published in Psychological Science, a journal of the Association for Psychological Science.

The research, led by Jay Sanguinetti of the University of Arizona, challenges currently accepted models about how the brain processes visual information.

Protein interplay in muscle tied to life span

PROVIDENCE, R.I. [Brown University] — Fruit flies are notoriously short-lived but scientists interested in the biology of aging in all animals have begun to understand why some fruit flies live longer than others. They have documented a direct association between insulin and life span, for example, and have observed a tradeoff between prolific reproduction and longevity.

Nicotine withdrawal traced to very specific group of brain cells

Nicotine withdrawal might take over your body, but it doesn't take over your brain. The symptoms of nicotine withdrawal are driven by a very specific group of neurons within a very specific brain region, according to a report in Current Biology, a Cell Press publication, on November 14. Although caution is warranted, the researchers say, the findings in mice suggest that therapies directed at this group of neurons might one day help people quit smoking.

Regenstrief and IU study: Older adults with severe mental illness challenge healthcare system

INDIANAPOLIS – Although older adults with serious mental illness didn't have more recorded physical illness and had fewer outpatient visits to primary care physicians, they made more medical emergency department visits and had considerably longer medical hospitalizations than older adults without mental illness according to a study conducted by researchers from the Regenstrief Institute and the Indiana University Center for Aging Research.

1 in 7 students has dabbled in 'smart' drugs

This news release is available in German.

American and European studies prove that students use prescription medication or drugs to enhance their cognitive performance. Researchers from the universities of Zurich and Basel examined whether Swiss students have also experimented with neuroenhancement and which substances they take by conducting a survey of 6,725 students with an average age of 23 at the two universities and ETH Zurich.

UC research brings a future of mind-reading robots ever closer

If you think with the release of every new i-device the world is getting closer to thought-controlled smart tech and robotic personal assistants, you might be right.

And thanks in part to work led by the University of Cincinnati's Anca Ralescu, we may be even closer than you realize.

Glowing worms illuminate the roots of behavior

Worcester, Mass. – A research team at Worcester Polytechnic Institute (WPI) and The Rockefeller University in New York has developed a novel system to image brain activity in multiple awake and unconstrained worms. The technology, which makes it possible to study the genetics and neural circuitry associated with animal behavior, can also be used as a high-throughput screening tool for drug development targeting autism, anxiety, depression, schizophrenia, and other brain disorders.

Are probiotics a promising treatment strategy for depression?

Philadelphia, PA, November 14, 2013 – Probiotics are not new, but their status as a nutritional buzzword is. Most folks have now heard and seen the term countless times in commercials and advertisements, as yogurt, dietary supplement, natural food product, and even cosmetic companies promote their probiotic-containing products.

IU cognitive scientists ID new mechanism at heart of early childhood learning and social behavior

BLOOMINGTON, Ind. -- Shifting the emphasis from gaze to hand, a study by Indiana University cognitive scientists provides compelling evidence for a new and possibly dominant way for social partners -- in this case, 1-year-olds and their parents -- to coordinate the process of joint attention, a key component of parent-child communication and early language learning.

Impulsivity, rewards and Ritalin: Monkey study shows tighter link

MADISON – Even as the rate of diagnosis has reached 11 percent among American children aged 4 to 17, neuroscientists are still trying to understand attention deficit hyperactivity disorder (ADHD). One classic symptom is impulsivity — the tendency to act before thinking.

Automated test construction can better assess student mastery of common core state standards

WASHINGTON, D.C., November 13, 2013 ─ The November 2013 issue of Educational Researcher (ER), a peer-reviewed journal of the American Educational Research Association (AERA), is now available on the association's website. Included in this issue is a report on an innovative algorithm for automated test construction that results in much more highly aligned – and therefore, more valid – assessments of student mastery of state content standards. The November issue of ER includes three feature articles and one essay.

Study: Your brain sees things you don't

University of Arizona doctoral degree candidate Jay Sanguinetti has authored a new study, published online in the journal Psychological Science, that indicates that the brain processes and understands visusal input that we may never consciously perceive. The finding challenges currently accepted models about how the brain processes visual information.

Gene linked to common intellectual disability

University of Adelaide researchers have taken a step forward in unravelling the causes of a commonly inherited intellectual disability, finding that a genetic mutation leads to a reduction in certain proteins in the brain.

ARX is among the top four types of intellectual disability linked to the X-chromosome in males. So far, 115 families, including many large Australian families, have been discovered to carry an ARX (Aristaless related homeobox) mutation that gives rise to intellectual disability.