Brain

Researchers from the Memory and Cognition Center at University Hospitals Case Medical Center will begin testing an intriguing new approach to slowing down the progression of Alzheimer's Disease (AD) using Intravenous Immune Globulin (IGIV), also known as gammaglobulin. IGIV is traditionally used to treat primary immunodeficiency disorders, but is not currently approved for treating AD, which is one of the leading causes of dementia in the elderly.

Do infants only start to crawl once they are physically able to see danger coming? Or is it that because they are more mobile, they develop the ability to sense looming danger? According to Ruud van der Weel and Audrey van der Meer, from the Norwegian University of Science and Technology in Trondheim, infants' ability to see whether an object is approaching on a direct collision course, and when it is likely to collide, develops around the time they become more mobile. Their findings (1) have just been published online in the Springer journal Naturwissenschaften.

Biotechnology and Biological Sciences Research Council (BBSRC)-funded research, published this week in Chemical Communications, describes how scientists have discovered molecules that could confuse insects' ability to detect plants by interfering with their sense of smell. This could reduce damage to crops by insect pests and contribute to food security.

Results: MIT engineers have designed a retinal implant for people who have lost their vision from retinitis pigmentosa or age-related macular degeneration, two of the leading causes of blindness. The retinal prosthesis would help restore some vision by electrically stimulating the nerve cells that normally carry visual input from the retina to the brain.

Contrary to the prevailing view, the hormone leptin, which is critical for normal food intake and metabolism, appears to regulate bone mass and suppress appetite by acting mainly through serotonin pathways in the brain, according to a recent study published in Cell by Yale School of Medicine researchers and colleagues at Columbia University. This new finding contradicts the view that leptin acts primarily in the hypothalamus.

Adolescent depression and anxiety disorders are two distinct psychiatric disorders, according to Dr. William W. Hale III (a researcher of the Langeveld Institute for the Study of Education and Development in Childhood and Adolescence at Utrecht University) in a recent publication in the Journal of Child Psychology and Psychiatry.

A new study explores how our brains synthesize concepts that allow us to organize and comprehend the world. The research, published by Cell Press in the September 24th issue of the journal Neuron, uses behavioral and neuroimaging techniques to track how conceptual knowledge emerges in the human brain and guides decision making.

Scientists now have a better understanding of a perplexing gene that is associated with susceptibility for a wide spectrum of severely debilitating mental illnesses. Two independent research studies published by Cell Press in the September 24th issue of the journal Neuron provide fascinating insight into the molecular mechanisms that link disrupted-in-schizophrenia 1 (DISC1) with the proper development and migration of neurons in the hippocampus, a brain area involved in learning and memory and associated with the pathology of schizophrenia.

LA JOLLA, CA—The brain never sits idle. Whether we are awake or asleep, watch TV or close our eyes, waves of spontaneous nerve signals wash through our brains. Researchers at the Salk Institute for Biological Studies studying visual attention have discovered a novel mechanism that explains how incoming sensory signals make themselves heard amidst the constant background rumblings so they can be reliably processed and passed on.

If you find yourself more concerned about highly publicized dangers that grab your immediate attention such as terrorist attacks, while forgetting about the more mundane threats such as global warming, you're not alone.

And you can't help it because it's human nature, according to a new study led by University of Colorado at Boulder psychology Professor Leaf Van Boven. That's because people tend to view their immediate emotions, such as their perceptions of threats or risks, as more intense and important than their previous emotions.

The organs of the inner ear have a direct effect on brain blood flow, independent of blood pressure and CO2 levels in the blood, say researchers writing in BMC Neuroscience who used a series of human centrifuge experiments to investigate the effects of stimulation of the otoliths and semi-circular canals on cerebrovascular response.

The standard explanation for what causes Alzheimer's is known as the amyloid hypothesis, which posits that the disease results from of an accumulation of the peptide amyloid beta, the toxic protein fragments that deposit in the brain and become the sticky plaques that have defined Alzheimer's for more than 100 years.

COLUMBIA, Mo. – About 2 million Americans currently use cocaine for its temporary side-effects of euphoria, which have contributed to making it one of the most dangerous and addictive drugs in the country. Cocaine addiction, which can cause severe biological and behavioral problems, is very difficult to overcome.

Washington, DC -- Researchers in the Memory Disorders Program at Georgetown University Medical Center are now recruiting volunteers for a national gene therapy trial – the first study of its kind for the treatment of patients with dementia due to Alzheimer's disease.

The first ever major study into adults living with autism was published today (Tuesday 22nd September) by the NHS Information Centre. The report, entitled 'Autism Spectrum Disorders in adults living in households throughout England 2007' was written by Professor Terry Brugha, a Consultant Psychiatrist with Leicestershire Partnership NHS Trust and Professor of Psychiatry at the University of Leicester with a team of UK researchers