Brain

Promising therapy for relapsing multibple sclerosis

SALT LAKE CITY – An international team of researchers has found that adding a humanized monoclonal antibody called daclizumab to standard treatment reduces the number of new or enlarged brain lesions in patients with relapsing multiple sclerosis. This new study was published online Feb. 16, 2010, and in the March edition of the Lancet Neurology.

Women, more than men, choose true crime over other violent nonfiction

CHAMPAIGN, Ill. — When it comes to violent nonfiction, men are from Mars, the planet of war, but women are from Earth, the planet of serial killings and random murders.

A new study found that, when given a choice of violent reading material, women overwhelmingly opted to read true stories about the death and dismemberment of victims much like themselves. Men, however, were more likely to choose nonfiction books about war or gang violence than those in the "true crime" genre.

The study appears in Social Psychological and Personality Science.

H1N1 learnings: Risk factors for severe outcomes among patients admitted to hospital with H1N1

A new study in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/cgi/doi/10.1503/cmaj.091823 of all patients in Canada admitted to hospital for H1N1 in the first five months of the outbreak summarizes the risk factors for a severe outcome (www.cmaj.ca). The H1N1 pandemic presents important learnings for clinicians and researchers and data on severe outcomes can help inform future treatment and prevention guidelines.

Focus on EU-funded research projects in trust and security

A special issue of the Journal of Computer Security (IOS Press, ISSN 0926-227X) brings together the research results of six ongoing FP6-IST projects. The editors of the journal invited those projects that received outstanding reviews in the ICT Trust and Security EU-calls to submit their papers.

Daclizumab shows potential for new immunoregulatory approach to treating MS

Cambridge, Mass. and Redwood City, Calif. – February 16, 2010 – Biogen Idec (NASDAQ: BIIB) and Facet Biotech Corporation (NASDAQ: FACT) today announced the publication of Phase 2 data showing that the addition of daclizumab to interferon beta (IFNβ) led to a significant reduction in the number of new or enlarged multiple sclerosis (MS) lesions when compared to IFNβ alone in patients with active relapsing forms of MS. The trial, called CHOICE, also showed that daclizumab led to an increase in a subset of the natural killer (NK) cells that help regulate the immune system.

Building fit minds under stress

PHILADELPHIA –- A University of Pennsylvania-led study in which training was provided to a high-stress U.S. military group preparing for deployment to Iraq has demonstrated a positive link between mindfulness training, or MT, and improvements in mood and working memory. Mindfulness is the ability to be aware and attentive of the present moment without emotional reactivity or volatility.

Report explains declining school performance

Housing segregation, making schooling a community matter, special teaching groups, individualisation and the right to freely choose which school to attend are factors explaining why Swedish school children perform worse than 20 years ago according to research at the University of Gothenburg, Sweden.

Teaching a foreign language? Best teach in the accent of the listener

Perception of second language speech is easier when it is spoken in the accent of the listener and not in the 'original' accent of that language, shows a new study from the University of Haifa. The study was published in the prestigious Journal of Psycholinguistic Research.

Autism's earliest symptoms not evident in children under 6 months

(SACRAMENTO, Calif.) — A study of the development of autism in infants, comparing the behavior of the siblings of children diagnosed with autism to that of babies developing normally, has found that the nascent symptoms of the condition — a lack of shared eye contact, smiling and communicative babbling — are not present at 6 months, but emerge gradually and only become apparent during the latter part of the first year of life.

Simple test may help judge concussion in athletes

ST. PAUL, Minn. – A simple test of reaction time may help determine whether athletes have sustained a concussion (also known as mild traumatic brain injury) and when they are ready to play again, according to a study released today that will be presented at the American Academy of Neurology's 62nd Annual Meeting in Toronto April 10 to April 17, 2010.

Common chromatin thread links multiple human cognitive disorders

A new study reveals that a common underlying mechanism is shared by a group of previously unrelated disorders which all cause complex defects in brain development and function. Rett syndrome (RTT), Cornelia de Lange syndrome (CdLS) and Alpha-Thalassemia mental Retardation, X-linked syndrome (ATR-X) have each been linked with distinct abnormalities in chromatin, the spools of proteins and DNA that make up chromosomes and control how genetic information is read in a cell.

Induced neural stem cells: Not quite ready for prime time

MADISON — The great promise of induced pluripotent stem cells is that the all-purpose cells seem capable of performing all the same tricks as embryonic stem cells, but without the controversy.

Brain-controlled cursor doubles as a neural workout

Harnessing brain signals to control keyboards, robots or prosthetic devices is an active area of medical research. Now a rare peek at a human brain hooked up to a computer shows that the two can adapt to each other quickly, and possibly to the brain's benefit.

New study possibly links cognitive and motor delays with 'flat head syndrome' in young babies

In a new study, infants averaging six months of age who exhibited positional plagiocephaly (flat head syndrome) had lower scores than typical infants in observational tests used to evaluate cognitive and motor development. Positional or deformational plagiocephaly may occur when external forces shape an infant's skull while it is still soft and malleable, such as extended time spent lying on a hard surface or in one position.

Caltech researchers obtain first brain recordings from behaving fruit flies

A puff of air was used to spur the flies into flapping their wings, while electrodes measured the activity of the marked neurons and high-speed digital cameras simultaneously recorded the flies' behavior.