A new study from MIT neuroscientists suggests that our ability to respond appropriately to intended harms — that is, with outrage toward the perpetrator — is seated in a brain region associated with regulating emotions.
Patients with damage to this brain area, known as the ventromedial prefrontal cortex (VMPC), are unable to conjure a normal emotional response to hypothetical situations in which a person tries, but fails, to kill another person. Therefore, they judge the situation based only on the outcome, and do not hold the attempted murderer morally responsible.