Brain

UM School of Medicine scientists develop new strategy that may improve cognition

For the first time, scientists have linked a brain compound called kynurenic acid to cognition, possibly opening doors for new ways to enhance memory function and treat catastrophic brain diseases, according to a new study from the University of Maryland School of Medicine. When researchers decreased the levels of kynurenic acid in the brains of mice, their cognition was shown to improve markedly, according to the study, which was published in the July issue of the journal Neuropsychopharmacology.

Impulsive, weak willed or just too much dopamine?

It's a common scenario: you're on a diet, determined to give up eating cakes, but as you pass the cake counter, all resolve disappears… Now, scientists at the Wellcome Trust Centre for Neuroimaging at UCL (University College London) have shed light on the brain processes that affect our will power and make us act impulsively.

New insights into link between anti-cholesterol statin drugs and depression

New insights into link between anti-cholesterol statin drugs and depression

ADAC: Restore hearing thanks to new drug

Researchers from the University of Auckland, New Zealand, have discovered that a potent new drug restores hearing after noise-induced hearing loss in rats. The landmark discovery found that injection of an agent called 'ADAC', activates adenosine receptors in cochlear tissues, resulting in recovery of hearing function. The finding paves the way for effective non-surgical therapies to restore hearing loss after noise-induced injury. Dr. Srdjan Vlajkovic and his team's work[1] is published in a special edition of Springer's journal Purinergic Signalling, focusing on the inner ear.

The ant queen's chemical crown

The defining feature of social insects is that societies contain queens, which specialise in laying eggs, as well as workers, which are mostly infertile but take care of the offspring and the nest. However, when the queen dies or is re-moved, workers begin laying eggs of their own. Previous observations have suggested that queens possess a specific pheromone which keeps the workers infer-tile, but the pheromone has never been identified except in the well-studied honeybee. Queen pheromones have a lot to tell us about how sociality evolved.

Teenage physical activity reduces risk of cognitive impairment in later life

Women who are physically active at any point over the life course (teenage, age 30, age 50, late life) have lower risk of cognitive impairment in late-life compared to those who are inactive, but teenage physical activity appears to be most important. This is the key finding of a study of over nine thousand women published today in the Journal of the American Geriatrics Society.

Can you make a snail forget?

Can you make a snail forget?

Predator scent enhanced the ability of pond snails (Lymnaea stagnalis) to form memory following training, whilst overcrowding and reduced calcium had a blocking effect.

"Understanding when stress blocks or enhances memory in a simple animal model may help elucidate the mechanisms in more complex animals such as humans", explained Dr Sarah Dalesman.

Key mechanism in how brain locates sound identified

Animals can locate the source of a sound by detecting microsecond (one millionth of a second) differences in arrival time at their two ears. New York University researchers have identified a mechanism the brain uses to help process sound localization. This group of scientists found that one reason these neurons are able to perform such a rapid and sensitive computation is because they are extremely responsive to the input's "rise time"—the time it takes to reach the peak of the synaptic input. The findings will publish next week in the online, open access journal PLoS Biology.

Depressed mice aid research on drug-resistant depression in humans

Depressed mice aid research on drug-resistant depression in humans

Is your left hand more motivated than your right hand?

Motivation doesn't have to be conscious; your brain can decide how much it wants something without input from your conscious mind. Now a new study shows that both halves of your brain don't even have to agree. Motivation can happen in one side of the brain at a time.

NYU researchers identify a key mechanism in the brain's computation of sound location

New York University researchers have identified a mechanism the brain uses to help process sound localization. Their findings, which appear in the latest edition of the journal PLoS Biology, focus on how the brain computes the different arrival times of sound into each ear to estimate the location of its source.

Impulsive, weak-willed or just too much dopamine?

It's a common scenario: you're on a diet, determined to give up eating cakes, but as you pass the cake counter, all resolve disappears… Now, scientists at the Wellcome Trust Centre for Neuroimaging at UCL (University College London) have shed light on the brain processes that affect our will power and make us act impulsively.

Brain's energy restored during sleep, suggests animal study

Brain's energy restored during sleep, suggests animal study

Washington, DC — In the initial stages of sleep, energy levels increase dramatically in brain regions found to be active during waking hours, according to new research in the June 30 issue of the Journal of Neuroscience. These results suggest that a surge of cellular energy may replenish brain processes needed to function normally while awake.

Examining risks and benefits of alcohol consumption

A discussion by renowned epidemiologist Kenneth Mukamal has recently been published in the Journal of the American Medical Association, JAMA. It provides a discussion in response to a theoretical question, - if you are a 42 year old male, should you drink alcohol ( in moderation) for your health?

Lead poisoning highly prevalent among school-aged children in Uganda

Researchers at Mount Sinai School of Medicine have found that children living near the Kiteezi landfill in Kampala, Uganda, have blood lead levels nearly 20 times as high as the typical lead level found in U.S. children. The data are published in the current issue of Environmental Health Perspectives.