Brain

Belmont, MA--Results of the first study of its kind to link abnormalities in circadian rhythms to changes in specific neurotransmitters in people with bipolar disorder will be published this week in the journal Biological Psychiatry.

Chronic stress can make us worn-out, anxious, depressed--in fact, it can change the architecture of the brain. New research at The Rockefeller University shows that when mice experience prolonged stress, structural changes occur within a little-studied region of their amygdala, a part of the brain that regulates basic emotions, such as fear and anxiety. These changes are linked to behaviors associated with anxiety and depressive disorders

There is good news, too: an experimental new drug might prevent these changes.

Scientists have confirmed one of the brain areas responsible for rapid updating of information during learning - the sort of information we use to negotiate many changing situations in everyday life.

COLUMBUS, Ohio - Simply telling people that their opinions are based on morality will make them stronger and more resistant to counterarguments, a new study suggests.

Researchers found that people were more likely to act on an opinion - what psychologists call an attitude - if it was labeled as moral and were more resistant to attempts to change their mind on that subject.

They were published in the current issue of the renowned journal "Science Signaling". The scientists provide evidence for the first time that treatment of Alzheimer transgenic model mice with an anti-platelet drug leads to significantly reduced amyloid plaques in cerebral vessels. They together with scientists from the Research Center Jülich, Germany, identified a key mechanism for a direct involvement of platelets in the progression of the disease.

When neurons die, their remains need to be eliminated quickly so that the surrounding brain tissue can continue functioning. A type of highly specialised cell known as microglia is responsible for this process which is called phagocytosis (derived from the Greek "phagein", to eat, and "kitos", cell). These tiny cells have numerous branches that are constantly on the move inside the brain and are specially equipped to detect and destroy any foreign element, including dead neurons. Or that is what has been believed until now.

PHILADELPHIA - Women who want to quit smoking may have better success by carefully timing their quit date with optimal days within their menstrual cycle, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania. The results, published online this month in Biology of Sex Differences, were also presented at the annual meeting of the Organization for the Study of Sex Differences (OSSD), held at Penn.

Rats that responded to cues for sugar with the speed and excitement of binge-eaters were less motivated for the treat when certain neurons were suppressed, researchers discovered.

COLUMBIA, Mo. - Wait lists for a specialist to confirm an autism diagnosis can be agonizing and last months. As the prevalence of autism and autism spectrum disorders increase, so does the demand for a health care system that is fully equipped to respond to the complex needs associated with autism. Now, Extension for Community Healthcare Outcomes (ECHO) Autism, a new program from the University of Missouri, is training primary care providers in best-practice care for autism spectrum disorders.

Adult songbirds modify their vocalizations when singing to juveniles in the same way that humans alter their speech when talking to babies. The resulting brain activity in young birds could shed light on speech learning and certain developmental disorders in humans, according to a study by McGill University researchers.

The dark side of painkillers - their dramatic increase in use and ability to trigger abuse, addiction and thousands of fatal overdoses annually in the United States is in the news virtually every day.

Brace for another shot across the bow: Opioids like morphine have now been shown to paradoxically cause an increase in chronic pain in lab rats, findings that could have far-reaching implications for humans, says a new study led by the University of Colorado Boulder.

Early exposure to nicotine can trigger widespread genetic changes that affect formation of connections between brain cells long after birth, a new Yale-led study has found. The finding helps explains why maternal smoking has been linked to behavioral changes such as attention deficit and hyperactivity disorder, addiction and conduct disorder.

Just as members of an orchestra need a conductor to stay on tempo, neurons in the brain need well-timed waves of activity to organize memories across time. In the hippocampus--the brain's memory center--temporal ordering of the neural code is important for building a mental map of where you've been, where you are, and where you are going. Published on May 30 in Nature Neuroscience, research from the RIKEN Brain Science Institute in Japan has pinpointed how the neurons that represent space in mice stay in time.

Research at the RIKEN Brain Science Institute in Japan has revealed that a molecule involved in fish reproduction activates the brain via the nose. The pheromone is released by female zebrafish and sensed by smell receptors in the noses of the males. The neural pathway and brain areas involved in transforming this molecular messenger into courtship behavior in fish were also identified and reported in Nature Neuroscience on May 30.

Research by Dr. Shernaz Bamji, from the University of British Columbia, uncovers the mechanism of action of an enzyme called DHHC9 in the normal development and function of neural networks in the brain. Mutations in DHHC9 have been identified in certain patients suffering from X-linked Intellectual Disability, however the specific role of DHHC9 was not known. Dr.