Proteins go everywhere in the cell and do all sorts of work, but a fundamental question has eluded biologists: How do the proteins know where to go?
"There's no little man sitting there, putting the protein in the right place," said Don Arnold, molecular and computational biologist at the USC College of Letters, Arts and Sciences.
"Proteins have to have in them encoded information that tells them where to go in the cell."
In a study appearing online this week in Nature Neuroscience, Arnold and collaborators solve the mystery for key proteins in the brain.