Brain

New insight into primate eye evolution

Researchers comparing the fetal development of the eye of the owl monkey with that of the capuchin monkey have found that only a minor difference in the timing of cell proliferation can explain the multiple anatomical differences in the two kinds of eyes.

Biological link established between tumors and depression

In a study that could help explain the connections between depression and cancer, researchers at the University of Chicago have used an animal model to find, for the first time, a biological link between tumors and negative mood changes.

The team determined that substances associated with depression are produced in increased quantities by tumors and are transmitted to the brain.

Additionally, pathways that normally moderate the impact of depression-causing substances are disrupted when a tumor develops.

New study may help understand how Alzheimer's robs sufferers of episodic memory

Athens, Ga. – Memory loss is love's great thief. Those who suffer aren't just the ones who can't remember—family, friends and loved ones agonize over how to react when the disorder begins its often inexorable progress.

Shire's INTUNIV (Guanfacine) extended release in children with ADHD and oppositional symptoms

San Francisco, CA – May 18, 2009 – Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, today announced new findings on INTUNIV (guanfacine) extended release, a selective alpha-2A-agonist, at a major psychiatric meeting. This randomized placebo controlled trial met its primary objective, which was to evaluate the effects of INTUNIV on oppositional symptoms in children aged 6 to 12 years with a diagnosis of ADHD and the presence of oppositional symptoms.

Computer model predicts brain tumor growth and evolution

PROVIDENCE, R.I. [Brown University] — Researchers from Brown University and other institutions have developed a computational computer model of how brain tumors grow and evolve.

The model is the product mathematical formulas based on the first principals of physics, such as conservation of mass, and it has allowed researchers to recreate tumor growth in a computer. Through subsequent repetitive testing against real tumors, they have also linked their computerized tumors to real-world brain tumors, or "gliomas," and can now watch tumor growth on a computer screen.

Synthetic catalyst mimics nature's 'hydrogen economy'

CHAMPAIGN, Ill. — By creating a model of the active site found in a naturally occurring enzyme, chemists at the University of Illinois have described a catalyst that acts like nature's most pervasive hydrogen processor.

The researchers describe their work in a paper accepted for publication in the Journal of the American Chemical Society, and posted on the journal's Web site.

Tumor growth and chemo response may be predicted by mathematical model

The aggressiveness of tumors and their susceptibility to chemotherapy may become easier to predict based on a mathematical model developed at The University of Texas Health Science Center at Houston.

Identification of a key molecular pathway required for brain neural circuit formation

Montréal, May 15, 2009 – The research group of Dr. Frédéric Charron, a researcher at the Institut de recherches cliniques de Montréal (IRCM), has made a discovery which could help treat spinal cord injuries and neurodegenerative diseases. This new finding has been published in the current issue of the prestigious scientific journal Neuron. Patricia T. Yam, Sébastien D. Langlois and Steves Morin, all at the IRCM, are listed as co-authors.

Brain's organization switches as children become adults

Any child confronting an outraged parent demanding to know "What were you thinking?" now has a new response: "Scientists have discovered that my brain is organized differently than yours."

But all is not well for errant kids. The same new study also provides parents with a rejoinder: While the overarching organization scheme differs, one of the most important core principals of adult brain organization is present in the brains of children as young as 7.

More older women with early stage breast cancer choose chemotherapy, GUMC researchers say

Washington, DC –A new study examining treatment decision-making by older women with early stage breast cancer shows that 45 percent of women would choose to get chemotherapy after surgery -- a figure higher than the national average of women getting the additional treatment.

Patient-centered approach to capturing data from cancer patients improves care and research

DURHAM, N.C. – Wireless, personal computers used by cancer patients to log their symptoms help improve the patients' care and further cancer research, according to a study led by researchers in the Duke Comprehensive Cancer Center.

Monkeys found to wonder what might have been

DURHAM, N.C. – Monkeys playing a game similar to "Let's Make A Deal" have revealed that their brains register missed opportunities and learn from their mistakes.

"This is the first evidence that monkeys, like people, have 'would-have, could-have, should-have' thoughts," said Ben Hayden, a researcher at the Duke University Medical Center and lead author of the study published in the journal Science.

Can you see the emotions I hear? Study says yes

By observing the pattern of activity in the brain, scientists have discovered they can "read" whether a person just heard words spoken in anger, joy, relief, or sadness. The discovery, reported online on May 14th in Current Biology, a Cell Press publication, is the first to show that emotional information is represented by distinct spatial signatures in the brain that can be generalized across speakers.

Brains or beauty: New study confirms having both leads to higher pay

WASHINGTON – People looking for a good job at a good salary could find their intelligence may not be the only trait that puts them at the top of the pay scale, according to researchers. A new study finds attractiveness, along with confidence, may help job-seekers stand out to employers.

Psychology research shows even in hostile working environments, employees reluctant to leave jobs

She never gets invited to lunch with the rest of her co-workers. He always gets publicly criticized for his mistakes.

But according to research by Kansas State University psychologists, neither of these workers is likely to leave the job.