Brain

Report offers framework for evaluating D.C. school reform efforts, along with first impressions

WASHINGTON — A new report from the National Research Council offers a framework for evaluating the effects of a 2007 reform law on the District of Columbia's public schools. The evaluation program must include systematic yearly public reporting of key data as well as in-depth studies of high-priority issues, such as teacher recruitment and retention, the report says. As part of the evaluation program, the Mayor's Office should produce an annual report to the city on the status of the public schools, including an analysis of trends and all the underlying data.

Virtual reality can improve design skills in younger generation

COLUMBIA, Mo. ¬— Rapidly improving technology is changing everyday life for all generations. This constantly changing environment can be a difficult adjustment for older generations. However, for the current generation known as "Generation Y", this sense of constant technology adaption isn't an adjustment; it is a way of life. A University of Missouri researcher says a widening gap is occurring between educators and students due to the difference in how older and younger generations approach evolving technologies.

Racial identity tied to happiness, study finds

EAST LANSING, Mich. — Black people who identify more strongly with their racial identity are generally happier, according to a study led by psychology researchers at Michigan State University.

The study, funded by the National Institute of Mental Health, appears in the current issue of Cultural Diversity and Ethnic Minority Psychology, a research journal published by the American Psychological Association.

Enzyme enhances, erases long-term memories in rats

Even long after it is formed, a memory in rats can be enhanced or erased by increasing or decreasing the activity of a brain enzyme, say researchers supported, in part, by the National Institutes of Health.

"Our study is the first to demonstrate that, in the context of a functioning brain in a behaving animal, a single molecule, PKMzeta, is both necessary and sufficient for maintaining long-term memory," explained Todd Sacktor, of the SUNY Downstate Medical Center, New York City, a grantee of the NIH's National Institute of Mental Health.

Human stem cells transformed into key neurons lost in Alzheimer's

CHICAGO --- Northwestern Medicine researchers for the first time have transformed a human embryonic stem cell into a critical type of neuron that dies early in Alzheimer's disease and is a major cause of memory loss.

This new ability to reprogram stem cells and grow a limitless supply of the human neurons will enable a rapid wave of drug testing for Alzheimer's disease, allow researchers to study why the neurons die and could potentially lead to transplanting the new neurons into people with Alzheimer's.

Brain rhythm predicts real-time sleep stability, may lead to more precise sleep medications

A new study finds that a brain rhythm considered the hallmark of wakefulness not only persists inconspicuously during sleep but also signifies an individual's vulnerability to disturbance by the outside world. In their report in the March 3 PLoS One, the team from the Massachusetts General Hospital (MGH) Division of Sleep Medicine uses computerized EEG signal processing to detect subtle fluctuations in the alpha rhythm during sleep and shows that greater alpha intensity is associated with increased sleep fragility.

Method developed to match police sketch, mug shot

The long-time practice of using police facial sketches to nab criminals has been, at best, an inexact art. But the process may soon be a little more exact thanks to the work of some Michigan State University researchers.

A team led by MSU University Distinguished Professor of Computer Science and Engineering Anil Jain and doctoral student Brendan Klare has developed a set of algorithms and created software that will automatically match hand-drawn facial sketches to mug shots that are stored in law enforcement databases.

Once in use, Klare said, the implications are huge.

Scripps Research study points to liver, not brain, as origin of Alzheimer's plaques

LA JOLLA, CA – March 3, 2011 – Unexpected results from a Scripps Research Institute and ModGene, LLC study could completely alter scientists' ideas about Alzheimer's disease—pointing to the liver instead of the brain as the source of the "amyloid" that deposits as brain plaques associated with this devastating condition. The findings could offer a relatively simple approach for Alzheimer's prevention and treatment.

The study was published online today in The Journal of Neuroscience Research.

Johns Hopkins team explores PARIS; finds a key to Parkinson's

Johns Hopkins scientists have discovered that PARIS — the protein — facilitates the most common form of Parkinson's disease (PD), which affects about 1 million older Americans. The findings of their study, published March 4 in Cell, could lead to important new targets for treatment.

Star-shaped brain cells feed long-term memory

Star-shaped cells in our brains called astrocytes were once considered little more than structures to fill the gaps between all-important neurons. But more recent evidence has emerged to reveal that those astrocytes play more than a supporting role; they are involved in information processing and signal transmission and they help to regulate the shapes of our neurons and their connections to one another.

Trouble with the latest dance move? GABA might be to blame

If you tend to have trouble picking up the latest dance moves or learning to play a new piano piece, there might be an explanation. A new study published online on March 3rd in Current Biology, a Cell Press publication, shows that people who are fast to learn a simple sequence of finger motions are also those whose brains show large changes in a particular chemical messenger following electrical stimulation.

Researchers find new mechanism behind the formation and maintenance of long-term memories

Researchers from Mount Sinai School of Medicine have found that lactate, a type of energy fuel in the brain, plays a critical role in the formation of long-term memory. These findings have important implications for common illnesses like Alzheimer's disease, other neurodegenerative disorders, aging-related memory impairment and diabetes. The research is published in the March 4th issue of the journal Cell.

Scientists identify susceptibility factor for bipolar disorder

A new study provides fascinating insight into the genetic basis of bipolar disorder, a highly heritable mood disorder characterized by recurrent episodes of mania and depression. The research, published by Cell Press online February 24 in the American Journal of Human Genetics, identifies a previously unrecognized susceptibility factor for bipolar disorder.

Discrimination creates racial battle fatigue for African-Americans

University Park, Pa. -- Just as the constant pressure soldiers face on the battlefield can follow them home in the form of debilitating stress, African Americans who face chronic exposure to racial discrimination may have an increased likelihood of suffering a race-based battle fatigue, according to Penn State researchers.

Better brain wiring linked to family genes

How well our brain functions is largely based on our family's genetic makeup, according to a University of Melbourne led study.

The study published in the international publication the Journal of Neuroscience provides the first evidence of a genetic effect on how 'cost-efficient' our brain network wiring is, shedding light on some of the brain's make up.