Recreational use of Ecstasy – the illegal "rave" drug that produces feelings of euphoria and emotional warmth – is associated with chronic changes in the human brain, Vanderbilt University investigators have discovered.
The findings, reported online Dec. 5 in the Archives of General Psychiatry, add to the growing evidence that Ecstasy produces long-lasting serotonin neurotoxicity in humans, said Ronald Cowan, M.D., Ph.D., associate professor of Psychiatry.