Brain

In recognizing faces, the whole is not greater than the sum of its parts

How do we recognize a face? To date, most research has answered "holistically": We look at all the features—eyes, nose, mouth—simultaneously and, perceiving the relationships among them, gain an advantage over taking in each feature individually. Now a new study overturns this theory. The researchers—Jason M. Gold and Patrick J. Mundy of the Indiana University and Bosco S. Tjan of the University of California Los Angeles—found that people's performance in recognizing a whole face is no better than their performance with each individual feature shown alone.

Brain cancer blood vessels not substantially tumor-derived, Johns Hopkins scientists report

Johns Hopkins scientists have published laboratory data refuting studies that suggest blood vessels that form within brain cancers are largely made up of cancer cells. The theory of cancer-based blood vessels calls into question the use and value of anticancer drugs that target these blood vessels, including bevacizumab (Avastin).

Revisiting LSD as a treatment for alcoholism

London, UK (March 9th, 2012) Several decades ago, a number of clinics used LSD to treat alcoholism with some success. But until now, no research has pulled together the results of these trials to document exactly how effective LSD was. Now a new meta-analysis of randomized controlled trials of the drug, available in the Journal of Psychopharmacology, published by SAGE, provides evidence for a clear and consistent beneficial effect of LSD for treating alcohol dependency.

Bias in decision-making leads to poor choices and may be linked to depression

When faced with making a complicated decision, our automatic instinct to avoid misfortune can result in missing out on rewards, and could even contribute to depression, according to new research.

Partnerships in the brain

Jülich/Wako-Shi March 8th, 2012 – How do neurons in the brain communicate with each other? One common theory suggests that individual cells do not exchange signals among each other, but rather that exchange takes place between groups of cells. Researchers from Japan, the United States and Germany have now developed a mathematical model that can be used to test this assumption. Their results have been published in the current issue of the journal PLoS Computational Biology.

Bias in decision-making leads to poor choices and possibly depression

When faced with making a complicated decision, our automatic instinct to avoid misfortune can result in missing out on rewards, and could even contribute to depression, according to new research.

Genetic manipulation boosts growth of brain cells linked to learning, enhances antidepressants

DALLAS -- UT Southwestern Medical Center investigators have identified a genetic manipulation that increases the development of neurons in the brain during aging and enhances the effect of antidepressant drugs.

The research finds that deleting the Nf1 gene in mice results in long-lasting improvements in neurogenesis, which in turn makes those in the test group more sensitive to the effects of antidepressants.

Let's raise a glass to, well, what's in the glass

BOSTON, MA—According to new research from Brigham and Women's Hospital (BWH), light-to-moderate alcohol consumption was associated with a lower risk of stroke in women.

The study will be electronically published on March 8, 2012 in Stroke, a journal of the American Heart Association (AHA).

Discovery of hair-cell roots suggests the brain modulates sound sensitivity

The hair cells of the inner ear have a previously unknown "root" extension that may allow them to communicate with nerve cells and the brain to regulate sensitivity to sound vibrations and head position, researchers at the University of Illinois at Chicago College of Medicine have discovered. Their finding is reported online in advance of print in the Proceedings of the National Academy of Sciences.

The hair-like structures, called stereocilia, are fairly rigid and are interlinked at their tops by structures called tip-links.

Teach your robot well (Georgia Tech shows how)

Within a decade, personal robots could become as common in U.S. homes as any other major appliance, and many if not most of these machines will be able to perform innumerable tasks not explicitly imagined by their manufacturers. This opens up a wider world of personal robotics, in which machines are doing anything their owners can program them to do—without actually being programmers.

Study pinpoints effects of different doses of an ADHD drug; Finds higher doses may harm learning

MADISON – New research with monkeys sheds light on how the drug methylphenidate may affect learning and memory in children with attention deficit hyperactivity disorder.

The results parallel a 1977 finding that a low dose of the drug boosted cognitive performance of children with ADHD, but a higher dose that reduced their hyperactivity also impaired their performance on a memory test.

Discovery of brain's natural resistance to drugs may offer clues to treating addiction

LA JOLLA, CA----A single injection of cocaine or methamphetamine in mice caused their brains to put the brakes on neurons that generate sensations of pleasure, and these cellular changes lasted for at least a week, according to research by scientists at the Salk Institute for Biological Studies.

Insects have personality too, research on honey bees indicates

CHAMPAIGN, Ill. — A new study in Science suggests that thrill-seeking is not limited to humans and other vertebrates. Some honey bees, too, are more likely than others to seek adventure. The brains of these novelty-seeking bees exhibit distinct patterns of gene activity in molecular pathways known to be associated with thrill-seeking in humans, researchers report.

Do you hear what I hear?

PASADENA, Calif.—In both animals and humans, vocal signals used for communication contain a wide array of different sounds that are determined by the vibrational frequencies of vocal cords. For example, the pitch of someone's voice, and how it changes as they are speaking, depends on a complex series of varying frequencies. Knowing how the brain sorts out these different frequencies—which are called frequency-modulated (FM) sweeps—is believed to be essential to understanding many hearing-related behaviors, like speech.

McGill researchers crack degeneration process that leads to Alzheimer's

A research group led by Dr. A. Claudio Cuello of McGill University's Faculty of Medicine, Dept. of Pharmacology and Therapeutics, has uncovered a critical process in understanding the degeneration of brain cells sensitive to Alzheimer's disease (AD). The study, published in the February issue of the Journal of Neuroscience, suggests that this discovery could help develop alternative AD therapies.