Brain

Modeling the demise of migrating brain tumor cells

An Israeli physicist has developed a theoretical model to simulate the evolution of highly proliferating brain tumour core cells subjected to treatment by alternating radio frequency electric field. The research, by Alexander Iomin from the Israel Institute of Technology Technion in Haifa, is about to be published in EPJ E¹. In another model, the author examines the possibility of enhancing the level of treatment by targeting the outer area of the tumour.

Study reports seizure-freedom in 68 percent of juvenile myoclonic epilepsy patients

A 25-year follow-up study reveals that 68% of patients with juvenile myoclonic epilepsy (JME) became seizure-free, with nearly 30% no longer needing antiepileptic drug (AED) treatment. Findings published today in Epilepsia, a journal of the International League Against Epilepsy (ILAE), report that the occurrence of generalized tonic-clonic seizures preceded by bilateral myoclonic seizures, and AED polytherapy significantly predicted poor long-term seizure outcome.

Between the ear and brain, an orderly orchestra of synapses

BUFFALO, N.Y. -- The brain receives information from the ear in a surprisingly orderly fashion, according to a University at Buffalo study scheduled to appear June 6 in the Journal of Neuroscience.

The research focuses on a section of the brain called the cochlear nucleus, the first way-station in the brain for information coming from the ear. In particular, the study examined tiny biological structures called synapses that transmit signals from the auditory nerve to the cochlear nucleus.

Antioxidant shows promise as therapy for some features of autism

Toronto, June 1, 2012 - A specific antioxidant supplement may be an effective therapy for some features of autism, according to a pilot trial from the Stanford University School of Medicine and Lucile Packard Children's Hospital that involved 31 children with the disorder.

The potential impact of olfactory stem cells as therapy reported in Cell Transplantation

Tampa, Fla. (June 5 , 2012) – A study characterizing the multipotency and transplantation value of olfactory stem cells, as well as the ease in obtaining them, has been published in a recent issue of Cell Transplantation (20:11/12), now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/.

Mothers' teen cannabinoid exposure may increase response of offspring to opiate drugs

GRAFTON, Mass. (June 5, 2012)—Mothers who use marijuana as teens—long before having children—may put their future children at a higher risk of drug abuse, new research suggests.

How immune system, inflammation may play role in Lou Gehrig's disease

FINDINGS:

In an early study, UCLA researchers found that the immune cells of patients with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, may play a role in damaging the neurons in the spinal cord. ALS is a disease of the nerve cells in the brain and spinal cord that control voluntary muscle movement.

Burden of full & subsyndromal PTSD in police who responded to the World Trade Center disaster

Amsterdam, The Netherlands, June 5, 2012 – Studies have found that police demonstrated considerable resilience to posttraumatic stress disorder (PTSD) compared to other disaster workers after the September 11, 2001 terrorist attack on the World Trade Center (WTC). This has been attributed to effective screening and extensive training in the police force.

Anxious girls' brains work harder

EAST LANSING, Mich. — In a discovery that could help in the identification and treatment of anxiety disorders, Michigan State University scientists say the brains of anxious girls work much harder than those of boys.

The finding stems from an experiment in which college students performed a relatively simple task while their brain activity was measured by an electrode cap. Only girls who identified themselves as particularly anxious or big worriers recorded high brain activity when they made mistakes during the task.

Post-stroke depression linked to functional brain impairment

OAK BROOK, Ill. – Researchers studying stroke patients have found a strong association between impairments in a network of the brain involved in emotional regulation and the severity of post-stroke depression. Results of the study are published online in the journal Radiology.

Food for thought? Study says soy may not help preserve thinking skills in women

MINNEAPOLIS – Contrary to earlier reports, a new study suggests that soy protein may not preserve overall thinking abilities in women over the age of 45, but may improve memory related to facial recognition. The study is published in the June 5, 2012, print issue of Neurology®, the medical journal of the American Academy of Neurology.

Stanford/USC study finds little cognitive benefit from soy supplements for older women

STANFORD, Calif. — In a new study of the effects of soy supplements for postmenopausal women, researchers at the Stanford University School of Medicine and the USC Keck School of Medicine found no significant differences — positive or negative — in overall mental abilities between those who took supplements and those who didn't.

Brain scans prove Freud right: Guilt plays key role in depression

Scientists have shown that the brains of people with depression respond differently to feelings of guilt – even after their symptoms have subsided.

University of Manchester researchers found that the brain scans of people with a history of depression differed in the regions associated with guilt and knowledge of socially acceptable behaviour from individuals who never get depressed.

Hands-on research

PASADENA, Calif.—A nuzzle of the neck, a stroke of the wrist, a brush of the knee—these caresses often signal a loving touch, but can also feel highly aversive, depending on who is delivering the touch, and to whom. Interested in how the brain makes connections between touch and emotion, neuroscientists at the California Institute of Technology (Caltech) have discovered that the association begins in the brain's primary somatosensory cortex, a region that, until now, was thought only to respond to basic touch, not to its emotional quality.

Mature liver cells may be better than stem cells for liver cell transplantation therapy

Tampa, Fla. (June 4, 2012) – After carrying out a study comparing the repopulation efficiency of immature hepatic stem/progenitor cells and mature hepatocytes transplanted into liver-injured rats, a research team from Sapporo, Japan concluded that mature hepatocytes offered better repopulation efficiency than stem/progenitor cells.