Brain

Leg compressions may enhance stroke recovery

AUGUSTA, Ga. – Successive, vigorous bouts of leg compressions following a stroke appear to trigger natural protective mechanisms that reduce damage, researchers report.

Compressing then releasing the leg for several five-minute intervals used in conjunction with the clot-buster tPA, essentially doubles efficacy, said Dr. David Hess, a stroke specialist who chairs the Medical College of Georgia Department of Neurology at Georgia Health Sciences University.

Mayo, UCSF team discovers genomic variant that increases risk of brain tumors

ROCHESTER, Minn. -- People who carry a "G" instead of an "A" at a specific spot in their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, a Mayo Clinic and University of California, San Francisco study has found.

Discovery: genomic variant that increases risk of some brain tumors

People who carry a "G" instead of an "A" at a specific spot in the sequence of their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, according to a study by researchers at the University of California, San Francisco and Mayo Clinic.

A lesson in sleep learning

Is sleep learning possible? A new Weizmann Institute study appearing today in Nature Neuroscience has found that if certain odors are presented after tones during sleep, people will start sniffing when they hear the tones alone – even when no odor is present – both during sleep and, later, when awake. In other words, people can learn new information while they sleep, and this can unconsciously modify their waking behavior.

Scientists identify new gene that influences survival in ALS

WORCESTER, MA — A team of scientists, including faculty at the University of Massachusetts Medical School (UMMS), have discovered a gene that influences survival time in amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease). The study, published today in Nature Medicine, describes how the loss of activity of a receptor called EphA4 substantially extends the lifespan of people with the disease.

Pitt: Targeted oxidation-blocker prevents secondary damage after traumatic brain injury

PITTSBURGH, Aug. 26, 2012 – Treatment with an agent that blocks the oxidation of an important component of the mitochondrial membrane prevented the secondary damage of severe traumatic brain injury and preserved function that would otherwise have been impaired, according to a research team from the University of Pittsburgh School of Medicine, Graduate School of Public Health and Department of Chemistry in a report published online today in Nature Neuroscience.

New device to remove stroke-causing blood clots proves better than standard tool

Stroke is the fourth leading cause of death and a common cause of long-term disability in the United States, but doctors have very few proven treatment methods. Now a new device that mechanically removes stroke-causing clots from the brain is being hailed as a game-changer.

Study: Clot removal devices successful tools for acute ischemic stroke treatment

Every 40 seconds, someone in the United States has a stroke, usually caused when a clot blocks an artery that supplies blood to the brain. Now the results of two multicenter studies published online in The Lancet on August 26 are giving physicians new innovative tools proven to better remove these clots that block blood flow.

Addressing the need for microscopic speed

Researchers at the University of Leicester have developed a new form of digital microscope which can create an image 100 times faster than regular equipment – without losing image quality.

The team of scientists have developed a new type of confocal microscope that produces high-resolution images at very fast speeds.

The findings are due to be published on the online journal PLOS ONE on August 24.

Discovery: new non-invasive method for diagnosing epilepsy

A team of University of Minnesota biomedical engineers and researchers from Mayo Clinic published a groundbreaking study today that outlines how a new type of non-invasive brain scan taken immediately after a seizure gives additional insight into possible causes and treatments for epilepsy patients. The new findings could specifically benefit millions of people who are unable to control their epilepsy with medication.

The research was published online today in BRAIN, a leading international journal of neurology.

The study's findings include:

Astrocytes control the generation of new neurons from neural stem cells

Astrocytes are cells that have many functions in the central nervous system, such as the control of neuronal synapses, blood flow, or the brain's response to neurotrauma or stroke.

Reduces brain tissue damage

Prof. Pekny's laboratory together with collaborators have earlier demonstrated that astrocytes reduce the brain tissue damage after stroke and that the integration of transplanted neural stem cells can be largely improved by modulating the activity of astrocytes.

Generation of new neurons

Nanoparticles reboot blood flow in brain

HOUSTON – (Aug. 23, 2012) – A nanoparticle developed at Rice University and tested in collaboration with Baylor College of Medicine (BCM) may bring great benefits to the emergency treatment of brain-injury victims, even those with mild injuries.

Combined polyethylene glycol-hydrophilic carbon clusters (PEG-HCC), already being tested to enhance cancer treatment, are also adept antioxidants. In animal studies, injections of PEG-HCC during initial treatment after an injury helped restore balance to the brain's vascular system.

IBC 2012: Mini-camera with maxi-brainpower

Just a few more meters to the finish line. The mountain biker jumps over the last hill and takes the final curve, with the rest of the competition close at his heels. At such moments, you do not want to just watch, you would really love to put yourself in the same shoes as the athlete. How does he push the pace on the final stretch? How fast is his pulse racing? What does he feel like? Viewers will soon be able to obtain this information in real time, directly with the images.

Novel microscopy method offers sharper view of brain's neural network

WASHINGTON, Aug. 23—Shortly after the Hubble Space Telescope went into orbit in 1990 it was discovered that the craft had blurred vision. Fortunately, Space Shuttle astronauts were able to remedy the problem a few years later with supplemental optics. Now, a team of Italian researchers has performed a similar sight-correcting feat for a microscope imaging technique designed to explore a universe seemingly as vast as Hubble's but at the opposite end of the size spectrum—the neural pathways of the brain.

Therapeutic avenues for Parkinson's investigated at UH

HOUSTON, Aug. 23, 2012 – Scientists at the University of Houston (UH) have discovered what may possibly be a key ingredient in the fight against Parkinson's disease.