Brain

Low ghrelin -- reducing appetite at the cost of increased stress?

Philadelphia, PA, September 13, 2012 – Ghrelin is a hormone released by the lining of the stomach that promotes feeding behavior. Decreasing ghrelin levels could potentially help combat obesity -- in fact, a vaccine that lowers ghrelin levels in order to reduce appetite is being studied as a treatment for obesity.

Low ghrelin - Reducing appetite at the cost of increased stress?

Philadelphia, PA, September 13, 2012 – Ghrelin is a hormone released by the lining of the stomach that promotes feeding behavior. Decreasing ghrelin levels could potentially help combat obesity -- in fact, a vaccine that lowers ghrelin levels in order to reduce appetite is being studied as a treatment for obesity.

Shine and rise

Inhibitory neurotransmitters dampen the activity of neurons. This regulatory effect forms the basis for the action of many anesthetics. For example, propofol, a common anesthetic, interacts with receptors on neural cell membranes that normally bind the inhibitory neurotransmitter gamma-amino butyric acid (GABA). Binding of GABA opens protein channels through which negatively charged chloride ions stream into the cell. By raising the resting electrical potential across the membrane, this makes the cell less likely to fire in response to an incoming stimulus.

Computer program can identify rough sketches

Getting a computer to understand what we've come to understand through years of cartoons and coloring books is a monumentally difficult task. The key to making this new program work, Hays says, is a large database of sketches that could be used to teach a computer how humans sketch objects. "This is really the first time anybody has examined a large database of actual sketches," Hays said.

Puberty turned on by brain during deep sleep

Chevy Chase, MD—Slow-wave sleep, or 'deep sleep', is intimately involved in the complex control of the onset of puberty, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM).

Antidepressants, sleeping pills and anxiety drugs may increase driving risk

Drugs prescribed to treat anxiety, depression and insomnia may increase patients' risk of being involved in motor vehicle accidents, according to a recent study, published in the British Journal of Clinical Pharmacology. Based on the findings, the researchers suggested doctors should consider advising patients not to drive while taking these drugs.

BYU study: Exercise may affect food motivation

It is commonly assumed that you can "work up an appetite" with a vigorous workout. Turns out that theory may not be completely accurate – at least immediately following exercise.

New research out of BYU shows that 45 minutes of moderate-to-vigorous exercise in the morning actually reduces a person's motivation for food.

Facebook profile pictures influence perceived attractiveness, MU study finds

COLUMBIA, Mo. -- Around the world, more than 850 million people use Facebook regularly to communicate. More and more employers also are using Facebook as a way to examine potential employees before making hires. Now, researchers at the University of Missouri have found that comments left by users on Facebook profile pictures strongly affect the level of perceived attractiveness of the profile owner physically, socially, and professionally.

Study examines thoughts and feelings that foster collaboration across cultures

NEW YORK -- September 12, 2012 -- The musician Paul Simon came to fame collaborating with his childhood friend Art Garfunkel, yet launched another chapter with his Graceland album, collaborating with musicians from Soweto. Ratan Tata made his name expanding his family's firms in India, yet in recent decades has reached even greater success helping foreign firms such as Daewoo and Jaguar find new markets.

Math anxiety causes trouble for students as early as first grade

Many high-achieving students experience math anxiety at a young age — a problem that can follow them throughout their lives, new research at the University of Chicago shows.

In a study of first- and second-graders, Sian Beilock, professor in psychology, found that students report worry and fear about doing math as early as first grade. Most surprisingly math anxiety harmed the highest-achieving students, who typically have the most working memory, Beilock and her colleagues found.

Stress hormones: Good or bad for posttraumatic stress disorder risk?

Philadelphia, PA, September 12, 2012 – Glucocorticoids, a group of hormones that includes cortisol, are considered stress hormones because their levels increase following stress. When their relationship to stress was first identified, it was shown that the release of cortisol prepared the body to cope with the physical demands of stress. Subsequently, high levels of cortisol were linked to depression and other stress-related disorders, giving rise to the hypothesis that high levels of cortisol on a long-term basis may impair the psychological capacity to cope with stress.

Genetic test predicts risk for Autism

A team of Australian researchers, led by University of Melbourne has developed a genetic test that is able to predict the risk of developing Autism Spectrum Disorder, ASD.

Lead researcher Professor Stan Skafidas, Director of the Centre for Neural Engineering at the University of Melbourne said the test could be used to assess the risk for developing the disorder.

"This test could assist in the early detection of the condition in babies and children and help in the early management of those who become diagnosed," he said.

Scientists discover how the brain ages

The ageing process has its roots deep within the cells and molecules that make up our bodies. Experts have previously identified the molecular pathway that react to cell damage and stems the cell's ability to divide, known as cell senescence.

However, in cells that do not have this ability to divide, such as neurons in the brain and elsewhere, little was understood of the ageing process. Now a team of scientists at Newcastle University, led by Professor Thomas von Zglinicki have shown that these cells follow the same pathway.

Investigators identify gene linking cataracts and Alzheimer's disease

(Boston) – In a recent study, investigators at Boston University Schools of Medicine (BUSM) and Public Health (BUSPH) identified a gene linking age-related cataracts and Alzheimer's disease. The findings, published online in PLoS ONE, contribute to the growing body of evidence showing that these two diseases, both associated with increasing age, may share common etiologic factors.

Fasting makes brain tumors more vulnerable to radiation therapy

A new study from USC researchers is the first to show that controlled fasting improves the effectiveness of radiation therapy in cancer treatments, extending life expectancy in mice with aggressive brain tumors.

Prior work by USC professor of gerontology and biological sciences Valter Longo, corresponding author on the study and director of the Longevity Institute at the USC Davis School of Gerontology, has shown that short-term fasting protects healthy cells while leaving cancer cells vulnerable to the toxic effects of chemotherapy.