Brain

Mechanism of breathing muscle 'paralysis' in dreaming sleep identified

A novel brain mechanism mediating the inhibition of the critical breathing muscles during rapid eye movement (REM) sleep has been identified for the first time in a new study, offering the possibility of a new treatment target for sleep-related breathing problems.

The findings were published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

Foetus suffers when mother lacks vitamin C

Maternal vitamin C deficiency during pregnancy can have serious consequences for the foetal brain. And once brain damage has occurred, it cannot be reversed by vitamin C supplements after birth. This is shown through new research at the University of Copenhagen just published in the scientific journal PLOS ONE.

Population studies show that between 10-20 per cent of all adults in the developed world suffer from vitamin C deficiency. Therefore, pregnant women should think twice about omitting the daily vitamin pill.

Uncommon features of Einstein's brain might explain his remarkable cognitive abilities

TALLAHASSEE, Fla. Portions of Albert Einstein's brain have been found to be unlike those of most people and could be related to his extraordinary cognitive abilities, according to a new study led by Florida State University evolutionary anthropologist Dean Falk.

Neurons made from stem cells drive brain activity after transplantation in laboratory model

LA JOLLA, Calif., November 15, 2012 – Researchers and patients look forward to the day when stem cells might be used to replace dying brain cells in Alzheimer's disease and other neurodegenerative conditions. Scientists are currently able to make neurons and other brain cells from stem cells, but getting these neurons to properly function when transplanted to the host has proven to be more difficult.

Barrow scientists discover ways to optimize light sources for vision

(Phoenix, AZ Nov. 15, 2012) -- Vision researchers at Barrow Neurological Institute have made a groundbreaking discovery into the optimization of light sources to human vision. By tuning lighting devices to work more efficiently with the human brain the researchers believe billions of dollars in energy costs could be saved.

Parkinson's disease protein causes disease spread and neuron death in healthy animals

PHILADELPHIA – Understanding how any disease progresses is one of the first and most important steps towards finding treatments to stop it. This has been the case for such brain-degenerating conditions as Alzheimer's disease. Now, after several years of incremental study, researchers at the Perelman School of Medicine, University of Pennsylvania have been able to piece together important steps in how Parkinson's disease (PD) spreads from cell to cell and leads to nerve cell death.

Researchers report potential new treatment to stop Alzheimer's disease

Last March, researchers at UCLA reported the development of a molecular compound called CLR01 that prevented toxic proteins associated with Parkinson's disease from binding together and killing the brain's neurons.

Building on those findings, they have now turned their attention to Alzheimer's disease, which is thought to be caused by a similar toxic aggregation or clumping, but with different proteins, especially amyloid-beta and tau.

Studies in Cell Transplantation investigate oxygen's impact as a factor in transplantation

Putnam Valley, NY. (Nov. 15, 2012) – Two studies published in the current issue of Cell Transplantation (21:7), now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/, investigate the role of oxygen in cell transplantation.

Study reveals insights that could aid in therapeutic use of mesenchymal stem cells

BOSTON – Mesenchymal stem cells (MSCs), are a newly emerging cellular therapy being tested in approximately 250 clinical trials worldwide to help repair damaged tissues, such as injured heart muscle following a heart attack. The problem is that when culture-expanded MSCs are injected into the circulation, they have trouble gaining access to the inflamed tissues—exactly where their help is needed.

Youth with autism gravitate toward STEM majors in college -- if they get there

It's a popularly held belief that individuals with an autism spectrum disorder (ASD) gravitate toward STEM majors in college (science, technology, engineering mathematics).

A new study, co-authored by Paul Shattuck, PhD, assistant professor at the Brown School at Washington University in St. Louis, confirms that view yet finds that young adults with an ASD also have one of the lowest overall college enrollment rates.

Study Tracks Brain Gene Response to Territorial Aggression

CHAMPAIGN, Ill. — With a mate and a nest to protect, the male threespined stickleback is a fierce fish, chasing and biting other males until they go away.

Now researchers are mapping the genetic underpinnings of the stickleback's aggressive behavior. Armed with tools that allow them to see which genes are activated or deactivated in response to social encounters, a team from the University of Illinois has identified broad patterns of gene activity that correspond to aggression in this fish.

Like a game of poker, school programs' success can hinge on principals going 'all in'

PITTSBURGH—When principals go "all in" in terms of supporting school programs, teachers stand a better chance of successfully implementing change, according to new research published by the University of Pittsburgh and the University of Virginia (UVA).

Eating more fish could reduce postpartum depression

When the going gets tough, the tough get... more relief from a placebo?

ANN ARBOR, Mich. — Are you good at coping when life gets tough? Do people call you a straight-shooter? Will you help others without expecting anything in return?

Those personality traits might do more than help you win a popularity contest. According to new University of Michigan-led neuroscience research, those qualities also might make you more likely to get pain relief from a placebo – a fake medicine.

Oxytocin keeps flirting folks at arm's length

Flirting brings women and men closer. But the "social distance" ensures that they will keep a certain spatial distance from each other. Researchers under the leadership of the University of Bonn studied whether this distance can be diminished by the so-called love hormone, oxytocin. The exact opposite turned out to be true – men who were in a committed relationship even maintained a greater distance from an attractive woman when under the influence of oxytocin than their control group. The study has just been published in the renowned "Journal of Neuroscience."