Brain

CentA1 study a major discovery for Alzheimer's disease

FLORIDA, March 19, 2013 – The Journal of Neuroscience has published a study led by researchers at the Max Planck Florida Institute for Neuroscience that may hold a stunning breakthrough in the fight to treat Alzheimer's disease. The study potentially identifies a cause of Alzheimer's disease—based on a newly-discovered signaling pathway in cellular models of Alzheimer's disease—and opens the door for new treatments by successfully blocking this pathway.

Mayo Clinic researchers develop test to gauge severity of concussions

SAN DIEGO — Neurologists at Mayo Clinic in Arizona have taken a promising step toward identifying a test that helps support the diagnosis of concussion. Their research has shown that autonomic reflex testing, which measures involuntary changes in heart rate and blood pressure, consistently appear to demonstrate significant changes in those with concussion. They presented the findings at the American Academy of Neurology annual meeting in San Diego this week.

Researchers identify a promising target for Multiple Sclerosis treatments

A team of basic and clinical scientists led by the University of Montreal Hospital* Research Centre's (CRCHUM) Dr. Nathalie Arbour has opened the door to significantly improved treatments for the symptoms of Multiple Sclerosis (MS). In a study selected as among the top 10% most interesting articles published in the Journal of Immunology, the team identifies the elevated presence in MS patients of a type of white blood cell (CD4 T cell) that expresses NKG2C, a highly-toxic molecule harmful to brain tissues.

Researchers identify a promising target for multiple sclerosis treatments

A team of basic and clinical scientists led by the University of Montreal Hospital* Research Centre's (CRCHUM) Dr. Nathalie Arbour has opened the door to significantly improved treatments for the symptoms of Multiple Sclerosis (MS). In a study selected as among the top 10% most interesting articles published in the Journal of Immunology, the team identifies the elevated presence in MS patients of a type of white blood cell (CD4 T cell) that expresses NKG2C, a highly-toxic molecule harmful to brain tissues.

Conscientious people are more likely to have higher GPAs

Conscientious people are more likely to have higher grade point averages, according to new research from psychologists at Rice University.

Brain-mapping increases understanding of alcohol's effects on first-year college students

A research team that includes several Penn State scientists has completed a first-of-its-kind longitudinal pilot study aimed at better understanding how the neural processes that underlie responses to alcohol-related cues change during students' first year of college.

Wireless, implanted sensor broadens range of brain research

A compact, self-contained sensor recorded and transmitted brain activity data wirelessly for more than a year in early stage animal tests, according to a study funded by the National Institutes of Health. In addition to allowing for more natural studies of brain activity in moving subjects, this implantable device represents a potential major step toward cord-free control of advanced prosthetics that move with the power of thought. The report is in the April 2013 issue of the Journal of Neural Engineering.

Combined hyperbaric O2 -- normobaric hyperoxia associated with improved outcome of severe TBI

Charlottesville, VA (March 19, 2013). Researchers at the Hennepin County Medical Center, University of Minnesota, and Minneapolis Medical Research Foundation (Minneapolis, Minnesota) report that the combined use of hyperbaric oxygen and normobaric hyperoxia therapies provides better outcomes in patients with severe traumatic brain injury (TBI) than the standard intensive neurosurgical care recommended for this injury.

Cell Transplantation study finds stem cells in deer antler

Putnam Valley, NY. (Mar. 19 2013) – A team of researchers in Seoul, Korea have reported finding evidence that deer antlers - unique in that they regenerate annually - contain multipotent stem cells that could be useful for tissue regeneration in veterinary medicine.

The study appears as an early e-publication for the journal Cell Transplantation, and is now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/pre-prints/ct0897seo.

Sleep study reveals how the adolescent brain makes the transition to mature thinking

(SACRAMENTO, Calif.) -- new study conducted by monitoring the brain waves of sleeping adolescents has found that remarkable changes occur in the brain as it prunes away neuronal connections and makes the major transition from childhood to adulthood.

Depression in Alzheimer's patients associated with declining ability to handle daily activities

New York, NY (March 18, 2013)—More symptoms of depression and lower cognitive status are independently associated with a more rapid decline in the ability to handle tasks of everyday living, according to a study by Columbia University Medical Center researchers in this month's Journal of Alzheimer's Disease.

False-Positive Mammography Results Cause Significant Long-Term Psychological Harm

False-positive results are a common unintended harmful effect of breast cancer screening mammography – the cumulative risk in Europe and the United States of false positives in 10 screening rounds ranges from 20 to 60 percent – and they have long-term psychosocial consequences.

Uncontrolled hypertension could bring increased risk for Alzheimer's disease

A study in the JAMA Neurology (formerly the Archives of Neurology) suggests that controlling or preventing risk factors such as hypertension earlier in life may limit or delay the brain changes associated with Alzheimer's disease and other age-related neurological deterioration.

Immortality gene mutation identifies brain tumors and other cancers

DURHAM, NC – Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research led by Duke Cancer Institute.

The finding, published Monday, March 18, 2013, in the journal Proceedings of the National Academy of Sciences, provides a long-sought answer to how some malignant cells are able to proliferate, while normal cells peter out and die.

Gone but not forgotten: Yearning for lost loved ones linked to altered thinking about the future

People suffering from complicated grief may have difficulty recalling specific events from their past or imagining specific events in the future, but not when those events involve the partner they lost, according to a new study published in Clinical Psychological Science, a journal of the Association for Psychological Science.