Brain

Xenon gas protects the brain after head injury

Treatment with xenon gas after a head injury reduces the extent of brain damage, according to a study in mice.

Exercise before school may reduce ADHD symptoms in kids

EAST LANSING, Mich. – Paying attention all day in school as a kid isn't easy, especially for those who are at a higher risk of ADHD, or attention deficit hyperactivity disorder.

A new study from Michigan State University and University of Vermont researchers shows that offering daily, before-school, aerobic activities to younger, at-risk children could help in reducing the symptoms of ADHD in the classroom and at home. Signs can include inattentiveness, moodiness and difficulty getting along with others.

Estrogen receptor expression may help explain why more males have autism

AUGUSTA, Ga. – The same sex hormone that helps protect females from stroke may also reduce their risk of autism, scientists say.

In the first look at a potential role of the female sex hormone in autism, researchers at the Medical College of Georgia at Georgia Regents University have found expression of estrogen receptor beta – which enables estrogen's potent brain protection – is significantly decreased in autistic brains. The receptor also plays a role in locomotion as well as behavior, including anxiety, depression, memory, and learning.

Eating habits, body fat related to differences in brain chemistry

People who are obese may be more susceptible to environmental food cues than their lean counterparts due to differences in brain chemistry that make eating more habitual and less rewarding, according to a National Institutes of Health study published in Molecular Psychiatry.

Intervention in 6-month-olds with autism eliminates symptoms, developmental delay

Treatment at the earliest age when symptoms of autism spectrum disorder (ASD) appear – sometimes in infants as young as 6 months old – significantly reduces symptoms so that, by age 3, most who received the therapy had neither ASD nor developmental delay, a UC Davis MIND Institute research study has found.

Sex hormones may play a part in autism

Higher rates of Autism Spectrum Disorders in males than females may be related to changes in the brain's estrogen signalling, according to research published in the open access journal Molecular Autism.

Broken signals lead to neurodegeneration

Researchers from the RIKEN Brain Science Institute in Japan, in collaboration with Juntendo University and the Japan Science and Technology Agency, have discovered that a cell receptor widely involved in intracellular calcium signaling--the IP3R receptor--can be locked into a closed state by enzyme action, and that this locking may potentially play a role in the reduction of neuron signaling seen in neurodegenerative diseases such as Huntington's and Alzheimer's disease.

In directing stem cells, study shows context matters

MADISON, Wis. — Figuring out how blank slate stem cells decide which kind of cell they want to be when they grow up — a muscle cell, a bone cell, a neuron — has been no small task for science.

Human pluripotent stem cells, the undifferentiated cells that have the potential to become any of the 220 types of cells in the body, are influenced in the lab dish by the cocktail of chemical factors and proteins upon which they are grown and nurtured. Depending on the combination of factors used in a culture, the cells can be coaxed to become specific types of cells.

Brain injuries no match for sPIF treatment

New Haven, Conn. — Researchers at Yale School of Medicine and their colleagues have uncovered a new pathway to help treat perinatal brain injuries. This research could also lead to treatments for traumatic brain injuries and neurodegenerative disorders such as Alzheimer’s and Parkinson’s.

The findings are published in the Sept. 8 issue of Proceedings of the National Academy of Sciences.

UCLA biologists delay the aging process by 'remote control'

UCLA biologists have identified a gene that can slow the aging process throughout the entire body when activated remotely in key organ systems.

Working with fruit flies, the life scientists activated a gene called AMPK that is a key energy sensor in cells; it gets activated when cellular energy levels are low.

Increasing the amount of AMPK in fruit flies' intestines increased their lifespans by about 30 percent — to roughly eight weeks from the typical six — and the flies stayed healthier longer as well.

Brain damage caused by severe sleep apnea is reversible

DARIEN, IL – A neuroimaging study is the first to show that white matter damage caused by severe obstructive sleep apnea can be reversed by continuous positive airway pressure therapy. The results underscore the importance of the "Stop the Snore" campaign of the National Healthy Sleep Awareness Project, a collaboration between the Centers for Disease Control and Prevention, American Academy of Sleep Medicine, Sleep Research Society and other partners.

Pastors get scant seminary training on how to help mentally ill, Baylor study finds

People struggling with mental illness often turn to pastors for help, but seminaries do very little to train ministers how to recognize serious psychological distress and when to refer someone to a doctor or psychologist, according to a Baylor University study.

As a result, "many people in congregations continue to suffer under well-meaning pastors who primarily tell them to pray harder or confess sin in relation to mental health problems," said lead researcher Matthew S. Stanford, Ph.D., professor of psychology and neuroscience in Baylor's College of Arts & Sciences.

Fish as good as chimpanzees at choosing the best partner for a task

Coral trout are fast when chasing prey above the reefs of their habitat, but can't pursue their quarry if it buries itself into a hard-to-reach reef crevice.

When this happens, the trout will team up with a snake-like moray eel to flush out the unfortunate fish in a remarkable piece of interspecies collaboration: either the eel takes the prey in the reef, or scares it back into the open so the trout can pounce.

Targeted immune booster removes toxic proteins in mouse model of Alzheimer's disease

Alzheimer's disease experts at NYU Langone Medical Center and elsewhere are reporting success in specifically harnessing a mouse's immune system to attack and remove the buildup of toxic proteins in the brain that are markers of the deadly neurodegenerative disease.

Food craving is stronger, but controllable, for kids

Children show stronger food craving than adolescents and adults, but they are also able to use a cognitive strategy that reduces craving, according to new research published in Psychological Science, a journal of the Association for Psychological Science.

"These findings are important because they suggest that we may have another tool in our toolbox to combat childhood obesity," says psychological scientist and lead researcher Jennifer A. Silvers, a post-doctoral fellow at Columbia University in the laboratory of Professor Kevin Ochsner.