Brain

Hunger games: How brain 'browns' fat to aid in weight loss

Researchers at Yale School of Medicine have uncovered a molecular process in the brain known to control eating that transforms white fat into brown fat. This process impacts how much energy we burn and how much weight we can lose. The results are published in the Oct. 9 issue of the journal Cell.

Oxytocin: How the 'love hormone' regulates sexual behavior

Oxytocin has been called the "love hormone" because it plays an important role in social behaviors, such as maternal care and pair bonding. In a study published by Cell Press on October 9th in the journal Cell, researchers uncover oxytocin-responsive brain cells that are necessary for female social interest in male mice during estrus—the sexually receptive phase of their cycle. These neurons, found in the prefrontal cortex, may play a role in other oxytocin-related social behaviors such as intimacy, love, or mother-child bonding.

Stanford team invents sensor that uses radio waves to detect subtle changes in pressure

Stanford engineers have invented a wireless pressure sensor that has already been used to measure brain pressure in lab mice with brain injuries.

The underlying technology has such broad potential that it could one day be used to create skin-like materials that can sense pressure, leading to prosthetic devices with the electronic equivalent of a sense of touch.

A nine-member research team led by Chemical Engineering Professor Zhenan Bao detailed two medical applications of this technology in Nature Communications.

Parental misconceptions about concussions could hinder treatment and recovery

SAN DIEGO – With football season in full swing, there's no shortage of talk about young players — from high school down to the pee wee levels — suffering from concussions. Yet many parents may lack knowledge about this mild traumatic brain injury, according to two studies to be presented Friday, Oct. 10 at a pre-conference symposium on pediatric sports medicine at the American Academy of Pediatrics (AAP) National Conference & Exhibition in San Diego.

Mechanism that repairs brain after stroke discovered

A previously unknown mechanism through which the brain produces new nerve cells after a stroke has been discovered at Lund University and Karolinska Institute in Sweden. The findings have been published in the journal SCIENCE.

An enzyme and synaptic plasticity

A small, "empty" space teeming with activity: a synapse is a complex structure where the neural (electrical) signal from the presynaptic neuron, as it travels towards its target –a muscle, a gland or another neuron – turns into a chemical signal capable of crossing the synaptic space before becoming electrical again once on the other side.

The specific receptor targeted by naltrexone to enhance diabetic wound closure is OGFr

A major complication associated with diabetes is delayed cell replication in epithelium and skin. Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have reported the presence and function of the opioid growth factor (OGF) and its nuclear-associated receptor (OGFr) in skin. OGF, an inhibitory growth factor, chemically termed [Met5]-enkephalin, can be upregulated in diabetes leading to depressed cell proliferation.

In-home visits reduce drug use, depression in pregnant teens

Intensive parenting and health education provided in homes of pregnant American Indian teens reduced the mothers' illegal drug use, depression and behavior problems, and set their young children on track to meet behavioral and emotional milestones they may have otherwise missed.

Manipulating memory with light

Just look into the light: not quite, but researchers at the UC Davis Center for Neuroscience and Department of Psychology have used light to erase specific memories in mice, and proved a basic theory of how different parts of the brain work together to retrieve episodic memories.

Optogenetics, pioneered by Karl Diesseroth at Stanford University, is a new technique for manipulating and studying nerve cells using light. The techniques of optogenetics are rapidly becoming the standard method for investigating brain function.

UCLA study finds link between neural stem cell overgrowth and autism-like behavior in mice

People with autism spectrum disorder often experience a period of accelerated brain growth after birth. No one knows why, or whether the change is linked to any specific behavioral changes.

A new study by UCLA researchers demonstrates how, in pregnant mice, inflammation, a first line defense of the immune system, can trigger an excessive division of neural stem cells that can cause "overgrowth" in the offspring's brain.

The paper appears Oct. 9 in the online edition of the journal Stem Cell Reports.

Mouse version of an autism spectrum disorder improves when diet includes a synthetic oil

When young mice with the rodent equivalent of a rare autism spectrum disorder (ASD), called Rett syndrome, were fed a diet supplemented with the synthetic oil triheptanoin, they lived longer than mice on regular diets. Importantly, their physical and behavioral symptoms were also less severe after being on the diet, according to results of new research from The Johns Hopkins University.

Online intervention tool for physician trainees may improve care of substance users

Online learning interventions and small group debriefings can improve medical residents' attitudes and communication skills toward patients with substance use disorders, and may result in improved care for these patients, according to a new study from the Perelman School of Medicine at the University of Pennsylvania and Drexel University College of Medicine published online in Academic Medicine.

Healthy lifestyle may cut stroke risk in half for women

MINNEAPOLIS – Women with a healthy diet and lifestyle may be less likely to have a stroke by more than half, according to a study published in the October 8, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

The study looked at five factors that make up a healthy lifestyle: healthy diet; moderate alcohol consumption; never smoking; physically active; and healthy body mass index (BMI). Compared with women with none of the five healthy factors, women with all five factors had a 54-percent lower risk of stroke.

Teens still sending naked selfies

A new study from the University of Utah confirms that substantial numbers of teens are sexting – sending and receiving explicit sexual images via cellphone. Though the behavior is widely studied, the potentially serious consequences of the practice led the researchers to more accurately measure how frequently teens are choosing to put themselves at risk in this fashion.

Deficits in tactile-based learning linked to Fragile X Syndrome

Researchers at Children's Hospital Los Angeles (CHLA) have described for the first time a specific perceptual learning deficit in mice with a mutation of the same gene as found in children with Fragile X Syndrome (FXS). Their findings, published on October 8 by PLOS ONE, may offer an effective pre-clinical platform for both investigating how brain circuitry is altered in FXS and testing drugs to improve these symptoms in children.