Brain

How gut bacteria may affect brain health

The hundred trillion bacteria living in an adult human, mostly in the intestines, making up the gut microbiome, may have a significant impact on behavior and brain health, according to a new paper.

The many ways gut bacteria can impact normal brain activity and development, affect sleep and stress responses, play a role in a variety of diseases, and be modified through diet for therapeutic use are described in a review article ("The Gut Microbiome and the Brain") in Journal of Medicinal Food.

Antisocial and normal siblings share difficulty recognizing emotions

Teenagers with brothers and sisters who exhibit severe antisocial behavior share a similar impairment with their siblings in recognizing emotions, according to a new study from the University of Southampton.

The findings suggest that difficulties in recognizing emotions could be a factor that increases a child's risk of developing conduct disorder - a condition characterized by pathological aggression and antisocial behavior.

Fatty acids in fish may shield brain from mercury damage

New findings from research in the Seychelles provide further evidence that the benefits of fish consumption on prenatal development may offset the risks associated with mercury exposure. In fact, the new study, which appears today in the American Journal of Clinical Nutrition, suggests that the nutrients found in fish have properties that protect the brain from the potential toxic effects of the chemical.

Regular Exercise May Boost Brain Health in Adults

In the brain, blood flow and cognitive function peak during young adulthood, but a new study of 52 young women found that oxygen availability, which is known to positively relate to brain health and function, is higher in adults who exercise regularly.

Women who exercised on a regular basis had higher oxygen availability in the anterior frontal region of the brain and performed best on difficult cognitive tasks.

fMRI: Men and women process emotions differently

Women rate emotional images as more emotionally stimulating than men do and are more likely to remember them. However, there are no gender-related differences in emotional appraisal as far as neutral images are concerned. These were the findings of a large-scale study by a research team at the University of Basel that focused on determining the gender-dependent relationship between emotions, memory performance and brain activity. The results will be published in the latest issue of the Journal of Neuroscience.

Genetic mutations in autism disorders

Recent research has linked autism with a lack of "pruning" in developing brain connections, but a new Dartmouth study suggests instead it is the excessive growth of new connections that causes sensory overload in people with the disorder.

The results, which have broad implications for understanding the neurobiological basis of autism spectrum disorders, appear in The Journal of Neuroscience. A PDF of the study is available on request.

Researchers discover 'idiosyncratic' brain patterns in autism

Autism Spectrum Disorder (ASD) has been studied for many years, but there are still many more questions than answers. For example, some research into the brain functions of individuals with autism spectrum have found a lack of synchronization ('connectivity') between different parts of the brain that normally work in tandem. But other studies have found the exact opposite - over-synchronization in the brains of those with ASD.

Brain recalls old memories via new pathways

People with anxiety disorders, such as post traumatic stress disorder (PTSD), often experience prolonged and exaggerated fearfulness. Now, an animal study suggests that this might involve disruption of a gradual shifting of brain circuitry for retrieving fear memories. Researchers funded by the National Institutes of Health have discovered in rats that an old fear memory is recalled by a separate brain pathway from the one originally used to recall it when it was fresh.

How the brain adapts to the restoration of eyesight

Recent scientific advances have meant that eyesight can be partially restored to those who previously would have been blind for life. However, scientists at the University of Montreal and the University of Trento have discovered that the rewiring of the senses that occurs in the brains of the long-term blind means that visual restoration may never be complete.

Targeting sugar attachment to BACE1 enzyme reduces Alzheimer's plaques

Researchers at the RIKEN-Max Planck Joint Research Center in Japan have demonstrated that hallmark symptoms of Alzheimer's disease can be reduced when sugars are prevented from binding to one of the key enzymes implicated in the disease. The new findings, reported in EMBO Molecular Medicine, show that abnormal attachment of a particular sugar to the enzyme BACE1 is a critical factor leading to the formation of Aβ plaques in the brain, and that plaques were reduced and cognitive performance improved when this action was prevented in mice through loss of the enzyme GnT-III.

Century-old drug reverses autism-like symptoms in fragile X mouse model

Autism spectrum disorders (ASD) affect 1 to 2 percent of children in the United States. Hundreds of genetic and environmental factors have been shown to increase the risk of ASD. Researchers at UC San Diego School of Medicine previously reported that a drug used for almost a century to treat trypanosomiasis, or sleeping sickness, reversed environmental autism-like symptoms in mice.

Closing your eyes really does boost memory recall

In a new paper published in Legal and Criminology Psychology, scholars from the University of Surrey have found evidence to suggest that eyewitnesses to crimes remember more accurate details when they close their eyes.

Serotonin neurons: Good things come to those who wait?

A new study found a causal link between the activation of serotonin neurons and the amount of time mice are willing to wait, and rejected a possible link between increased serotonin neuron activation and reward.

Folic acid saves 1,300 babies each year from brain and spine birth defects

Fortifying grain foods with the B vitamin folic acid has saved about 1,300 babies every year from being born with serious birth defects of the brain and spine known as neural tube defects (NTDs), according to new data published by the US Centers for Disease Control and Prevention in its publication Morbidity and Mortality Weekly Report (MMWR).The number of babies born in the United States with these conditions has declined by 35 percent since 1998.

Alzheimer's foreshadowing: Depression, behavior changes even before memory

Depression and other behavior changes may show up in people who will later develop Alzheimer's disease even before they start having memory problems, according to a new study published in the January 14, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.