Brain

Neurogenesis -- discovery of a new regulatory mechanism

Bassem Hassan's* team at VIB/KU Leuven has discovered a previously unknown mechanism that is highly conserved between species and which regulates neurogenesis through precise temporal control of the activity of a family of proteins essential for brain development: the proneural proteins. This mechanism, a simple reversible chemical modification, is critical for the production of a sufficient number of neurons, their differentiation and the development of the nervous system.

This plant sucks! (But how?)

The bladderwort has a trap faster than the blink of an eye. It uses powerful suction to snatch its prey. A recently published review is helping reveal exactly how a plant can suck so much.

Could blood pressure drugs have a role in Alzheimer's disease treatment?

WASHINGTON (Jan. 29, 2016) -- In laboratory neuronal cultures, an FDA-approved drug used to treat high blood pressure reduced cell damage often linked to Alzheimer's disease, say researchers at Georgetown University Medical Center (GUMC) and the National Institutes of Health.

Finger tracing can lift student performance in maths

Students who trace certain maths problems with a finger are able to solve them more quickly and easily, University of Sydney research shows.

Studies involving 275 Sydney school children aged between nine and 13 found that tracing over elements of maths problems enhanced how they understood and solved problems in geometry and algebra.

Tests revealed students who used their finger to trace over practice examples while simultaneously reading geometry or arithmetic material were able to complete tasks more quickly and correctly than those who did not use the same technique.

Graphene shown to safely interact with neurons in the brain

Researchers have successfully demonstrated how it is possible to interface graphene - a two-dimensional form of carbon - with neurons, or nerve cells, while maintaining the integrity of these vital cells. The work may be used to build graphene-based electrodes that can safely be implanted in the brain, offering promise for the restoration of sensory functions for amputee or paralysed patients, or for individuals with motor disorders such as epilepsy or Parkinson's disease.

Hearing aids improve memory, speech

A recent study by Jamie Desjardins, Ph.D., an assistant professor in the speech-language pathology program at The University of Texas at El Paso, found that hearing aids improve brain function in persons with hearing loss.

Hearing loss, if left untreated, can lead to serious emotional and social consequences, reduced job performance and diminished quality of life. Untreated hearing loss also can interfere with cognitive abilities because so much effort is put toward understanding speech.

Virtual reality makes its best users the most queasy

MADISON, Wis. -- In a twist of virtual fate, people with the best 3-D vision are also the people most likely to suffer from motion sickness while using virtual reality displays.

Researchers at the University of Wisconsin-Madison demonstrated this irony by playing motion-heavy videos for study participants through the Oculus Rift -- a 3-D virtual reality headset worn like a pair of goggles.

Study reveals subtle brain differences in men with autism

Research at King's College London has revealed subtle brain differences in adult males with autism spectrum disorder (ASD), which may go some way towards explaining why symptoms persist into adulthood in some people with the disorder.

New therapy halts progression of Lou Gehrig's disease in mice

CORVALLIS, Ore. - Researchers at Oregon State University announced today that they have essentially stopped the progression of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, for nearly two years in one type of mouse model used to study the disease - allowing the mice to approach their normal lifespan.

The findings, scientists indicate, are some of the most compelling ever produced in the search for a therapy for ALS, a debilitating and fatal disease, and were just published in Neurobiology of Disease.

IU, Regenstrief study: Cognitive training effects differ by older adult's education level

INDIANAPOLIS -- The first study to investigate the effects of cognitive training on the cognitive functioning of older adults by education level has found that individuals with fewer than 12 years of schooling benefit more from cognitive training than their more highly educated counterparts.

Researchers' preclinical trial upends conventional wisdom about responses to fear

Fear. You've been there: Your heart races, even jumps to your throat. Your hands grow clammy and your stomach churns. Your mind goes blank.

Rats have been there, too. We don't know their feelings, of course, but we do know their response: They freeze in their tracks. Or at least that's been the consensus among scientists since 1899, when experimental psychologist Willard Stanton Small first noted the behavior.

But now new research led by Rebecca Shansky, assistant professor of psychology at Northeastern University, upends that conventional wisdom.

It's complicated: Benefits and toxicity of anti-prion antibodies in the brain

Immunotherapy to ameliorate neurodegeneration by targeting brain protein aggregates with antibodies is an area of intense investigation. A study published on January 28th in PLOS Pathogens examines seemingly contradictory earlier results of targeting the prion protein and proposes a cautionary way forward to further test related therapeutic approaches.

Scientists decode brain signals nearly at speed of perception

Using electrodes implanted in the temporal lobes of awake patients, scientists have decoded brain signals at nearly the speed of perception. Further, analysis of patients' neural responses to two categories of visual stimuli - images of faces and houses - enabled the scientists to subsequently predict which images the patients were viewing, and when, with better than 95 percent accuracy.

The research is published today in PLOS Computational Biology.

How severe maternal inflammation can lead to autism-like behavior

CAMBRIDGE, MA -- In 2010, a large study in Denmark found that women who suffered an infection severe enough to require hospitalization while pregnant were much more likely to have a child with autism (even though the overall risk of delivering a child with autism remained low).

Treating Parkinson's disease by solving the mysteries of movement

Two secrets of one of the brain's most enigmatic regions have finally been revealed. In a pair of new studies, scientists from the Gladstone Institutes have discovered a specific neural circuit that controls walking, and they found that input to this circuit is disrupted in Parkinson's disease.