Brain

THC makes rats lazy, less willing to try cognitively demanding tasks: UBC study

New research from the University of British Columbia suggests there may be some truth to the belief that marijuana use causes laziness-- at least in rats.

The study, published today in the Journal of Psychiatry and Neuroscience, found that tetrahydrocannabinol (THC), the main psychoactive ingredient in marijuana, makes rats less willing to try a cognitively demanding task.

Whiskers help animals sense the direction of the wind

Many animals appear to have an impressive ability to follow the wind to find food, avoid predators, and connect with potential mates. Until now, however, no study had examined how land mammals know the direction of the wind. New research finds that an important part of this ability lies in an animal's whiskers. The work could pave the way for the design of novel airflow measurement devices that imitate these biological sensors.

NEJM study: MRI-guided focused ultrasound effective to treat essential tremor

Baltimore, Md., Aug. 25, 2016 - Treatment with MRI-guided focused ultrasound significantly improves tremors and quality of life in patients with essential tremor (ET), the most common movement disorder, according to a study published in the August 25 issue of the New England Journal of Medicine. Researchers at the University of Maryland School of Medicine (UM SOM), were among an international group of investigators studying this new noninvasive treatment, which was recently approved by the U.S. Food and Drug Administration (FDA), based on this research.

Breakthrough in understanding of brain development: Immune cell involvement revealed

Okazaki, Japan - Microglia are cells that combat various brain diseases and injuries by swallowing foreign or disruptive objects and releasing molecules that activate repair mechanisms. Recent findings have suggested these brain cells are also active under normal conditions, where they can contribute to maturation and sculpting of neuronal circuits. Researchers centered at the National Institute for Physiological Sciences (NIPS) have now revealed new mechanisms by which microglia sculpt neural circuits.

Elevating brain protein allays symptoms of Alzheimer's and improves memory

LA JOLLA--Boosting levels of a specific protein in the brain alleviates hallmark features of Alzheimer's disease in a mouse model of the disorder, according to new research published online August 25, 2016 in Scientific Reports.

The protein, called neuregulin-1, has many forms and functions across the brain and is already a potential target for brain disorders such as Parkinson's disease, amyotrophic lateral sclerosis and schizophrenia.

A brain circuit to push past nutritional stress

When we go hungry, we have the ability to ignore the urge to eat such that we can carry out the task at hand. It has long been known that the brain is involved in such decisions. But how the brain coordinates the response to nutritional stress so that the body can function normally is not understood very well. Now, researchers from the National Centre for Biological Sciences (NCBS), Bangalore, have discovered a brain circuit that allows fruit flies to take a major developmental step in their lives despite nutritional stress.

Childhood head injury linked to higher risk of poor adult mental health and life chances

Childhood brain injuries, including concussions, are associated with an increased risk of subsequent mental illness, poor school attainment and premature death, according to a study published today in PLOS Medicine.

A research team, based in the UK, US and Sweden, funded by Wellcome, analysed data from more than a million Swedes born between 1973 and 1985 to examine the long-term impact of having a traumatic brain injury before the age of 25.

Intravenous glyburide treatment may reduce dangerous brain swelling after stroke

A phase 2 clinical trial of a drug that may alleviate brain swelling -- a dangerous stroke complication -- suggests the treatment may help reduce brain injury and death, and information from the study will help design the phase 3 trial. While the trial did not meet its prespecified primary objective, as described in a paper receiving online release in The Lancet Neurology, it did provide additional evidence that intravenous glyburide treatment may improve patient outcomes.

In some genetic cases of microcephaly, stem cells fail to launch

In a very severe, genetic form of microcephaly, stem cells in the brain fail to divide, according to a new Columbia University Medical Center study that may provide important clues to understanding how the Zika virus affects the developing brain.

The study was published August 24 in Nature Communications.

Due to the Zika virus, the world is suffering from its first known epidemic of microcephaly, a devastating brain developmental condition that substantially reduces the number of neurons in the brain, along with brain size and function at birth.

Traumatic brain injury associated with long-term psychosocial outcomes

Traumatic brain injury (TBI) during youth is associated with elevated risks of impaired adult functioning, according to a longitudinal study published in PLOS Medicine. The study, conducted by Seena Fazel of the University of Oxford, United Kingdom, and colleagues, demonstrates that children and adolescents experiencing even milder forms of TBI (including concussion) may have reduced longevity and significant psychosocial problems in adulthood.

MRI scans may be useful in diagnosing chronic traumatic encephalopathy, UCLA study shows

UCLA doctors have found what may be an earlier and easier way to diagnose chronic traumatic encephalopathy, or CTE, a disorder that is thought to affect some former football players and others with a history of repetitive brain trauma.

Using a new software tool for analyzing MRI scans, the researchers detected the shrinkage of several key brain regions in a former football player with cognitive problems. The same pattern of brain changes is commonly seen in CTE cases that have been confirmed by autopsies after a person's death.

Evidence of changes to children's brain rhythms following 'brain training'

New research questions the strong claims that have been made about the benefits of 'brain training' - enhanced mental skills, a boost to education, improved clinical outcomes and sharper everyday functioning. This new study found evidence that 'brain training' changed brain signalling but no indication of other benefits.

New report details pre- and postnatal brain defects from Zika virus

OAK BROOK, Ill. - The journal Radiology has published a special report, detailing the spectrum of imaging findings in babies and fetuses infected with the Zika virus.

Surprise discovery in the blink of an eye

We probably do it every day, but scientists have only just discovered a distinct new way in which we move our eyes.

The team from the University of Tübingen in Germany assessed the eye movements of 11 subjects using tiny wires attached to the cornea and with infrared video tracking. In results published in eLife, they discovered a new type of eye movement that is synchronised with blinking.

Texas A&M research shows standing desks lower BMI

(COLLEGE STATION, Texas) -- Most of us have heard that standing desks are good for us, and it makes sense it would also be good for our children. Now, for the first time, there's evidence that this simple change in classroom furniture can slow the increase in elementary school children's body mass index (BMI) -- a key indicator of obesity -- by an average of 5.24 percentile points, according to research published today in the American Journal of Public Health.