Body

First human gene implicated in regulating length of human sleep

Scientists have discovered the first gene involved in regulating the optimal length of human sleep, offering a window into a key aspect of slumber, an enigmatic phenomenon that is critical to human physical and mental health.

Mango seeds may protect against deadly food bacteria

Life in the fruit bowl is no longer the pits, thanks to a University of Alberta researcher.

Christina Engels has found a way to turn the throwaway kernels in mangos into a natural food preservative that could help prevent Listeriosis outbreaks like the one that killed 21 Canadians last year.

Little safe haven for sexually assaulted LGBTQ victims

Being a victim of sexual assault and seeking help is difficult for anyone, but when the victim is lesbian, gay, bisexual, transgender and/or queer (LGBTQ) the thought of reporting a crime may well be laced with added layers of uncertainty and mistrust, according to a study in Oregon.

Neurological complications of heart surgery

MAYWOOD, Ill. – Possible neurological complications of heart surgery, ranging from headaches to strokes, are detailed in a new report in the online journal MedLink Neurology.

The review article, which compiled results of previously published studies, was written by Dr. Betsy Love, Dr. Sara Hocker and senior author Dr. Jose Biller of Loyola University Chicago's Stritch School of Medicine.

New method takes aim at aggressive cancer cells

Cambridge, MA. Thurs. August 13, 2009 — A multi-institutional team of Boston-area researchers has discovered a chemical that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed new tumors.

MRC scientists advance understanding of cell death

Medical Research Council (MRC) scientists have made an important advance in understanding the biological processes involved when cells are prompted to die. The work may help scientists to eventually develop new treatments for the many common diseases and conditions which occur when cell death goes wrong.

First compound that specifically kills cancer stem cells found

The cancer stem cells that drive tumor growth and resist chemotherapies and radiation treatments that kill other cancer cells aren't invincible after all. Researchers reporting online on August 13th in the journal Cell, a Cell Press publication, have discovered the first compound that targets those cancer stem cells directly.

"It wasn't clear it would be possible to find compounds that selectively kill cancer stem cells," said Piyush Gupta of the Massachusetts Institute of Technology (MIT) and the Broad Institute. "We've shown it can be done."

Protein plays unexpected role protecting chromosome tips

HOUSTON - A protein specialist that opens the genomic door for DNA repair and gene expression also turns out to be a multi-tasking workhorse that protects the tips of chromosomes and dabbles in a protein-destruction complex, a team lead by researchers at The University of Texas M. D. Anderson Cancer Center reports in the Aug. 13 edition of Molecular Cell.

Technique enables efficient gene splicing in human embryonic stem cells

p>CAMBRIDGE, Mass. (August 13, 2009) – A novel technique allows researchers to efficiently and precisely modify or introduce genes into the genomes of human embryonic stem cells (ESCs) and induced pluripotent stem (iPS) cells, according to Whitehead scientists. The method uses proteins called zinc finger nucleases and is described in the August 13 issue of Nature Biotechnology.

For years, scientists have easily swapped genes in and out of mouse ESC or iPS cell genomes, but have had a notoriously difficult time disrupting or inserting genes into their human equivalents.

Thanks to protein-based injection, heart disease patients could soon bypass surgery

Although open-heart surgery is a frequent treatment for heart disease, it remains extremely dangerous. Now groundbreaking research from Dr. Britta Hardy of Tel Aviv University's Sackler School of Medicine has shown the potential for an injected protein to regrow blood vessels in the human heart ― eliminating the need for risky surgery altogether.

Scientists conduct shark survey off US East Coast

Sandbar, dusky and tiger sharks are among dozens of shark species living in the coastal waters off the U.S. East Coast. Little is known about many of the species, but a survey begun nearly 25 years ago is helping scientists and fishery resource managers to monitor shark populations and their role in marine ecosystems.

Imidacloprid remains highly effective, global flea monitoring program concludes

SHAWNEE, Kan, 08/13/2009 – Bayer Animal Health announced today at the 22nd World Association for the Advancement of Veterinary Parasitology (WAAVP), Calgary, Canada the latest results of a large-scale, international, independent Flea Susceptibility Monitoring (FSM) program, demonstrating that imidacloprid remains highly effective for the control of fleas in companion animals.

Ultrabithorax: the driving force behind water strider evolution

Water striders, the familiar semi-aquatic bugs gliding across the lake at the cottage, have a novel body form that allows them to walk on water. This was not always the case. Achieving the gliding ability required the evolution of a unique arrangement of the legs, with the mid-legs greatly elongated. Scientists at the University of Toronto's Department of Ecology and Evolutionary Biology have discovered the gene behind this evolutionary change.

Cancer mortality rates dropping steadily as prevention and treatment efforts improve

Grand Rapids, Mich. (Aug. 13, 2009) – The number of cancer deaths has declined steadily in the last three decades. Although younger people have experienced the steepest declines, all age groups have shown some improvement, according to a recent report in Cancer Research, a journal of the American Association for Cancer Research.

Virologists getting closer to new porcine circovirus vaccine

Porcine circovirus associated diseases cost pig producers around the world hundreds of millions of dollars each year.

That's why Kansas State University virologists Dick Hesse and Bob Rowland have been working to create new vaccines to tackle such complex diseases.

"Circovirus and its associated diseases continue to emerge around the world," Hesse said. "Both porcine reproductive and respiratory syndrome and circovirus are a worldwide problem and they continue to evolve."