Body

Blocking IL-17RA signaling may protect against acute lung injury

New Orleans, LA – Research led by Dr. Jay Kolls, Professor and Chairman of Genetics at LSU Health Sciences Center New Orleans, has identified a therapeutic target for acute lung injury resulting in acute respiratory distress syndrome, a highly fatal complication of influenza infection. The research will be published in The Journal of Immunology in October.

Telltale moss provides new compass for stem cell research

Hikers know that moss on a tree trunk always points north. According to new research by Israeli and German scientists, this ancient plant may also provide a new "compass" for stem cell research, telling scientists how better to program stem cells for medical purposes.

Was mighty T. rex 'Sue' felled by a lowly parasite?

MADISON — When pondering the demise of a famous dinosaur such as 'Sue,' the mighty Tyrannosaurus rex whose fossilized remains are a star attraction of the Field Museum in Chicago, it is hard to avoid the image of clashing Cretaceous titans engaged in bloody, mortal combat.

It is an image commonly promoted by museums and dinosaur aficionados. Sue's remains, in fact, exhibit holes in her jaw that some believed were battle scars, the result of conflict with another dinosaur, possibly another T. rex.

Security of biological select agents and toxins

A new report from the National Research Council, RESPONSIBLE RESEARCH WITH BIOLOGICAL SELECT AGENTS AND TOXINS, assesses the efficacy of regulations, procedures, and oversight that have been instituted to safeguard against the deliberate misuse of biological select agents and toxins (BSAT) used in research. The report looks at security programs designed to protect against external threats, as well as internal threats from laboratory personnel. The report also makes recommendations on refining security programs and procedures with the aim of informing policy discussions in the U.S.

Arsenic toxic at low levels, ferrate oxidation is innovative approach to mediate

Although arsenic (As) occurs ubiquitously in the environment and has been used since its isolation in 1250 A.D in various fields such as medicine, metallurgy, agriculture and electronics, it is undoubtedly best known for its toxicity to both plants and animals. The toxic effects of arsenic in humans range from skin lesions to cancer of the brain, liver, kidney and stomach. Generally inorganic arsenic species are more toxic to humans and other animals than organic forms.

Self-monitoring of blood glucose

Diabetes patients should always control their own blood sugar values if this leads to improvements in their treatment. This is the view advocated by Michael Nauck of the Bad Lauterberg Diabetes Center and his coauthors in the current issue of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2009; 106[37]: 587-94), who discuss sensible approaches to blood glucose self-monitoring.

On the basis of their analysis, the authors make differentiated proposals for the cost-efficient self-monitoring of blood glucose in a manner appropriate to the patient's individual needs.

New perspectives on cancer surgery

Transgenic songbirds and the molecular biology of vocal learning

You can learn a lot from an animal. By manipulating the DNA of mice, flies, frogs and worms, scientists have discovered a great deal about the genes and molecules behind many of life's essential processes. These basic functions often work about the same in people as they do in "model" animals. But if you want to study more sophisticated cognitive processes such as humans' ability to learn language from one another, you need a more sophisticated organism.

Is obesity alone really to blame for osteoarthritis?

DURHAM, N.C. – The link between obesity and osteoarthritis may be more than just the wear and tear on the skeleton caused by added weight.

A Duke University study has found that the absence of the appetite hormone leptin can determine whether obese mice experience arthritis, no matter how heavy they are.

PCPs are front line defense in diagnosing serious illness in patients with acute lower back pain

A study by researchers at The George Institute for International Health in Australia found that it is rare for patients presenting to PCPs with acute lower back pain to have previously undiagnosed serious diseases. The most common serious disease cause documented was vertebral fracture, with half of the cases identified at the time of initial consultation. Full findings appear in the October issue of Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.

Study suggests obesity alone does not cause knee osteoarthritis in mice

In 2005 the World Health Organization (WHO) estimated that globally 400 million adults were obese, defined by a body mass index (BMI) of 30 kg/m2 or greater. WHO projects that by 2015 there will be more than 700 million obese adults worldwide. Obesity is considered to be one of the greatest risk factors for osteoarthritis, a progressive musculoskeletal disorder that is characterized by loss of joint cartilage.

Women who make poor shoe choices at risk for foot pain later in life

A recently published study determined that women who make poor shoe choices early in life suffer with foot pain in later years. Research shows that men do not experience the same foot pain as women, due to type of shoes they wear. Details of this study appear in the October issue of Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.

Attention paramedics: uninterrupted chest-compressions key to surviving cardiac arrest

DALLAS – Sept. 29, 2009 – Maximizing the proportion of time spent performing chest compressions during cardiopulmonary resuscitation (CPR) substantially improves survival in patients who suffer cardiac arrest outside a hospital setting, according to a multicenter clinical study that included UT Southwestern Medical Center.

Risk of bone fractures associated with use of thiazolidinediones

Research published this week in the open access journal, PLoS Medicine, suggests that there is an association between thiazolidinediones – a type of drug introduced in the 1990s to treat type 2 diabetes – and bone fracture.

Treatment for dementia associated with risk of hospitalization Psychotic illness and cannabis

Laura Park-Wyllie and colleagues, from St Michael's Hospital, Toronto, examined the health records of more than 1.4 million older adults in Ontario and showed that initiation of cholinesterase inhibitor therapy – a common treatment for dementia –is associated with a more than doubling of the risk of hospitalization for bradycardia.