Body

COLUMBUS, Ohio – Scientists here have identified how the motions of an enzyme are related to correctly copying genetic instructions, setting the stage for studies that can uncover what happens when DNA copying mistakes are made.

Perpetuation of DNA mistakes can cause mutations that lead to cancer and other diseases.

But before scientists can determine how and when errors are made during DNA replication, they must first fully understand what's going on when the copying process works properly – a monumental research pursuit that remains incomplete.

For men coping with painful erections lasting for long periods of time, or priapism, new research published online in The FASEB Journal (http://www.fasebj.org) offers hope. That's because researchers from the United States and China show that the enzyme adenosine deaminase may prevent priapism from progressing to penile fibrosis, a condition associated with the build up of scar tissue and eventual impotence. As penile fibrosis is a complication of priapism, so priapism is a complication of sickle cell disease.

A new study published in the journal Paediatric and Perinatal Epidemiology reveals that anxiety in pregnant women impacts their babies' size and gestational age. Specifically, women with more severe and chronic anxiety during pregnancy are more likely to have affected babies.

Prozac works wonders for some depressed people, but not for others. In some cases, patients derive little benefit and at worst, it can lead to bizarre hallucinations and fits of rage. Researchers and doctors remain puzzled as to what causes the wide range of reaction to Prozac and similar antidepressants.

The answer, Tel Aviv University researchers believe, can be found in a patient's genes. And if their research is successful, these scientists may be able to provide psychiatrists with a simple genetic test to revolutionize the treatment of depression.

Millions of people around the world use medicines based on statins to lower their blood cholesterol, but new research from the University of Gothenburg, published in the prestigious journal PNAS, shows that statins may also be effective in the treatment of cancer.

Chevy Chase, MD—Stem cell research holds great promise for the treatment of millions of Americans with debilitating and possibly fatal diseases. Current legislation and guidelines, however, continue to limit researchers' endeavors in unlocking the potential breakthroughs that stem cell research can provide.

Growing concerns about health has caused the scientific community to focus their interest on investigating functional foods which contribute to boosting the prevention and reduction of the risk of suffering from certain illnesses. The benefits of this product lies in its composition and, thus, its study, identification and subsequent extraction provides a useful tool which enables making high added-value products, given their high concentration of biologically active compounds.

Cornell researchers have discovered a genetic mechanism in fruit flies that prevents two closely related species from reproducing, a finding that offers clues to how species evolve.

When two populations of a species become geographically isolated from each other, their genes diverge from one another over time.

Eventually, when a male from one group mates with a female from the other group, the offspring will die or be born sterile, as crosses between horses and donkeys produce sterile mules. At this point, they have become two distinct species.

An Australian method for assessing the environmental impact of marine fisheries has caught the eye of fishery management agencies worldwide.

Aspects of the 'ecological risk assessment' (ERA) method have been adopted in the US, Canada, Ecuador, and the Western and Central Pacific, and by the international eco-labelling organisation the Marine Stewardship Council.

The method was developed in research led by Dr Tony Smith and Dr Alistair Hobday from CSIRO's Wealth from Oceans Flagship in association with the Australian Fisheries Management Authority (AFMA).

Edmonton – Even one cigarette has serious adverse effects on young adults, according to research presented by Dr. Stella Daskalopoulou at the Canadian Cardiovascular Congress 2009, co-hosted by the Heart and Stroke Foundation and the Canadian Cardiovascular Society.

Her study found that smoking one cigarette increases the stiffness of the arteries in 18 to 30 year olds by a whopping 25 per cent.

Arteries that are stiff or rigid increase resistance in the blood vessels, making the heart work harder. The stiffer the artery, the greater the risk for heart disease or stroke.

Edmonton – Adding ezetimibe to atorvastatin significantly boosted the attainment of lipid targets as specified by both Canadian and European guidelines in elderly patients aged 65 and older and the combination produced superior results than simply increasing the dose of atorvastatin alone, Dr. Christian Constance told the Canadian Cardiovascular Congress 2009, co-hosted by the Heart and Stroke Foundation and the Canadian Cardiovascular Society.

DALLAS – Oct. 27, 2009 – UT Southwestern Medical Center patient Michael LeBlanc, 40, is the first in North Texas to receive the newest generation of a mechanical device designed to improve heart function. It will be his lifeline while he awaits a heart transplant.

It is possible to simultaneously survey a number of neglected tropical diseases (NTDs) in the challenging environment of Southern Sudan, according to a new study published October 27 in the open-access journal PLoS Neglected Tropical Diseases.

Research published this week in PLoS Medicine challenges the dogma of the antibody-dependent enhancement model (ADE) for the development of dengue hemorrhagic fever (DHF).