Body

Heavy alcohol consumption may increase breast cancer recurrence risk

SAN ANTONIO – Moderate to heavy consumption of alcoholic beverages (at least three to four drinks per week) is associated with a 1.3-fold increased risk of breast cancer recurrence. Women who are post-menopausal or overweight may be most susceptible to the effects of alcohol on recurrence. Drinking less than three drinks per week was not associated with an increased risk.

University of Alberta researchers develop drug interface to save lives

A drug information interface system developed by two University of Alberta researchers has been shown to help in dealing with visual and motor impairments, which can make sorting, holding and indentifying pills a challenge as we age.

Potential new heart attack biomarker uncovered

Though they remain a leading killer, heart attacks can be effectively treated provided they can be rapidly diagnosed following initial onset of symptoms. In a study appearing in this month's Molecular and Cellular Proteomics, researchers have identified cardiac myosin-binding protein C (cMyBP-C) as a potential new diagnostic biomarker for heart attacks, one that may be particularly valuable for mild attacks in which traditional diagnostic proteins may not be abundant enough.

Study reveals H1N1's unexpected weakness--hemagglutinin 'hook'

The H1N1 influenza virus has been keeping a secret that may be the key to defeating it and other flu viruses as well.

Researchers at Rice University and Baylor College of Medicine (BCM) have found what they believe is a weakness in H1N1's method for evading detection by the immune system.

Synthetic protein mimics structure, function of metalloprotein in nature

CHAMPAIGN, Ill. — Scientists have designed a synthetic protein that is both a structural model and a functional model of a native protein, nitric-oxide reductase.

The designed protein "provides an excellent model system for studying nitric-oxide reductase, and for creating biocatalysts for biotechnological, environmental and pharmaceutical applications," said University of Illinois chemistry professor Yi Lu, who directed the work.

Introns: A mystery renewed

BLOOMINGTON, Ind. -- The sequences of nonsense DNA that interrupt genes could be far more important to the evolution of genomes than previously thought, according to a recent Science report by Indiana University Bloomington and University of New Hampshire biologists.

Hebrew University, American researchers show 'trigger' to stem cell differentiation

Jerusalem – A gene which is essential for stem cells' capabilities to become any cell type has been identified by researchers at the Hebrew University of Jerusalem and the University of California, San Francisco.

The discovery represents a further step in the ever-expanding field of understanding the ways in which stem cells develop into specific cells, a necessary prelude towards the use of stem cell therapy as a means to reverse the consequences of disease and disability.

Uniform analyses for clean drinking water in Europe

DNA sheds new light on horse evolution

Ancient DNA retrieved from extinct horse species from around the world has challenged one of the textbook examples of evolution – the fossil record of the horse family Equidae over the past 55 million years.

The study, published today in the Proceedings of the National Academy of Sciences, involved an international team of researchers and the Australian Centre for Ancient DNA (ACAD) based at the University of Adelaide.

Only the modern horse, zebras, wild asses and donkey survive today, but many other lineages have become extinct over the last 50,000 years.

From fruit fly wings to heart failure -- why Not(ch)?

Monterotondo, 10 December 2009 - Almost a century after it was discovered in fruit flies with notches in their wings, the Notch signalling pathway may come to play an important role in the recovery from heart attacks. In a study published today in Circulation Research, scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, are the first to prove that this signalling pathway targets heart muscle cells and thus reveal its crucial role in heart development and repair.

Surgical quality program is a strong tool for assessing outcomes for high-risk procedures

CHICAGO (December 10, 2009) – New research published in the December issue of the Journal of the American College of Surgeons finds that the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) is a powerful tool for assessing outcomes of uncommon, high-risk surgical procedures, including pancreatic necrosectomy. This is the first time that national data on this particular procedure has been available and analyzed, and the data from ACS NSQIP showed that patients undergoing pancreatic necrosectomy had better outcomes than predicted.

Abundance of a look-alike species clouds population status of a million dollar fish

FT. LAUDERDALE, FL, December 10, 2009 - The prized white marlin, sought by anglers in million dollar prize tournaments and captured incidentally in commercial fisheries, is among the most overfished marine species under international management and the subject of contentious debate on how to best achieve its recovery. Now a new study published today in the journal Endangered Species Research casts uncertainty on the accuracy of current knowledge of white marlin biology and previous population assessments, which form the basis of management and conservation policy.

Members of the European Parliament discuss achieving heart health in Europe

Brussels, 9 December 2009 - Members of the European Parliament Heart Group (MEP HG) meet today, in Brussels, with the Cardiology profession and representatives of national Heart Foundations to evaluate the achievements at EU level in combating Cardiovascular Disease (CVD), and to reveal the need for further action.

'Mini' transplant may reverse severe sickle cell disease

Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that "mini" stem cell transplantation may safely reverse severe sickle cell disease in adults.

The phase I/II study to establish safety of the procedure, published December 10 in the New England Journal of Medicine, describes 10 patients with severe sickle cell disease who received intravenous transplants of blood-forming stem cells. The transplanted stem cells came from the peripheral blood of healthy related donors matched to the patients' tissue types.

Experiment grows real human bone in tissue culture

The best way to prevent a fracture is to stop bones from reaching the point where they are prone to breaking, but understanding the process of how bones form and mature has been challenging. Now researchers at the University of Houston department of health and human performance have created a process that grows real human bone in tissue culture, which can be used to investigate how bones form and grow.