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Soybean genome analysis reveals pathways for improving biodiesel

WALNUT CREEK, CA—Soybean, one of the most important global sources of protein and oil, is now the first legume species with a published complete draft genome sequence. The sequence and its analysis appear in the January 14 edition of the journal Nature. The research team comprised 18 institutions, including the U.S. Department of Energy Joint Genome Institute (DOE JGI), the U.S. Department of Agriculture-Agricultural Research Service (USDA-ARS), Purdue University and the University of North Carolina at Charlotte.

Paradigm changing mechanism is revealed for the control of gene expression in bacteria

(New York, NY, January 13, 2009) A new study led by researchers at NYU Langone Medical Center is shedding new light on the action of Rho, a key regulatory protein in E. coli and many other bacteria. The study published in the January 14, 2010 issue of Nature reveals a new paradigm to understand the molecular principles of gene transcription. This work could potentially lead to the development of new types of antibiotics that could target Rho and its crucial functions.

USDA scientists, collaborators sequence soybean genome

WASHINGTON, Jan. 13, 2010 -- U.S. Department of Agriculture (USDA) scientists are part of a team that has sequenced the majority of the soybean genome, providing an unprecedented look into how this important legume crop converts four critical ingredients--sunlight, water, carbon dioxide and nitrogen--into protein and oil, the basic building blocks for many consumer products. The research team from 18 federal, state, public and private organizations published their research today in the journal Nature.

Chimp and human Y chromosomes evolving faster than expected

CAMBRIDGE, Mass. (January 13, 2010) – Contrary to a widely held scientific theory that the mammalian Y chromosome is slowly decaying or stagnating, new evidence suggests that in fact the Y is actually evolving quite rapidly through continuous, wholesale renovation.

The viruses within -- and what keeps them there

It is known that viral "squatters" comprise nearly half of our genetic code. These genomic invaders inserted their DNA into our own millions of years ago when they infected our ancestors. But just how we keep them quiet and prevent them from attack was more of a mystery until EPFL researchers revived them.

Mutations in different cells cooperate to set the stage for cancer

According to modern biology textbooks, a single genetic mutation is rarely enough to cause cancer. It is generally thought that cells must accumulate a series of mutations that work together to trigger tumor development. Now, Howard Hughes Medical Institute (HHMI) researchers have shown that distinct cancer-causing mutations in neighboring cells can cooperate to produce tumors.

Wildlife Conservation Society finds 'world's least known bird' breeding in Afghanistan

Researchers for the Wildlife Conservation Society have discovered for the first time the breeding area of the large-billed reed warbler—dubbed in 2007 as "the world's least known bird species"—in the remote and rugged Wakhan Corridor of the Pamir Mountains of north-eastern Afghanistan.

Using a combination of astute field observations, museum specimens, DNA sequencing, and the first known audio recording of the species, researchers verified the discovery by capturing and releasing almost 20 birds earlier this year, the largest number ever recorded.

Seeing the forest through the trees and seeing the trees through the leaves

Since the time of the earliest humans, people have attempted to understand the natural environment. We have observed our surroundings and searched for explanations for natural phenomena. Yet despite our persistence over thousands of years, many basic questions remain to be answered. Although we understand core processes such as photosynthesis, we do not have a full understanding of issues such as how plants maximize their photosynthetic capacity.

Scent of a woman: Men's testosterone responses to olfactory ovulation cues

Women around the world spend billions of dollars each year on exotic smelling perfumes and lotions in the hopes of attracting a mate. However, according to a new study in Psychological Science, a journal of the Association for Psychological Science, going "au natural" may be the best way to capture a potential mate's attention.

Prevalence of high body mass index among children and teens remains steady

The prevalence of high weight for length or high body mass index (BMI) among children and teens in the U.S. (i.e., at or above the 95th percentile), ranges from approximately 10 percent for infants and toddlers, to approximately 18 percent for adolescents and teenagers, although these rates appear to have remained relatively stable over the past 10 years, except for an increase for 6- to 19-year-old boys who are at the very heaviest weight levels, according to a study appearing in the January 20 issue of JAMA.

TGen-Scottsdale Healthcare researchers make breakthrough in lung cancer

SCOTTSDALE, Ariz. — Jan. 13, 2010 — Researchers for TGen Clinical Research Services at Scottsdale Healthcare (TCRS) have identified a way to predict which patients with small-cell lung cancer may be resistant to first-line chemotherapy.

The study, Tumor MicroRNA Biomarkers Associated with De Novo Chemoresistance in Small Cell Lung Cancer, will be presented today in San Diego at a joint conference of the American Association for Cancer Research (AACR) and the International Association for the Study of Lung Cancer (IASLC).

Words used to describe substance-use patients can alter attitudes, contribute to stigma

Changing the words used to describe someone struggling with alcoholism or drug addiction may significantly alter the attitudes of health care professionals, even those who specialize in addiction treatment. Massachusetts General Hospital (MGH) researchers have found that health professionals' answers to survey questions about a hypothetical patient varied depending on whether he was described as a "substance abuser" or as "having a substance use disorder." Their study will appear in the International Journal of Drug Policy and has been released online.

CSHL scientists use next-gen sequencing to rapidly discover genetic cause of devastating disorder

Cold Spring Harbor, N.Y. – Two scientists from Cold Spring Harbor Laboratory (CSHL) are part of an international team that has discovered a genetic mutation that causes Joubert Syndrome. JBTS, as it is commonly called, is a devastating inherited neurological disease that is very rare in the general population but found relatively more often among Ashkenazi Jews.

Key piece of puzzle sheds light on function of ribosomes

When ribosomes produce protein in all living cells, they do so through a chemical reaction that happens so fast that scientists have been puzzled. Using large quantum mechanical calculations of the reaction center of the ribosome, researchers at Uppsala University in Sweden can now provide the first detailed picture of the reaction. The findings are published in the Web edition of Proceedings of the National Academy of Sciences, PNAS.

Analysis of new data confirms bisphenol A link to disease in adults

Researchers from the Peninsula Medical School and the University of Exeter, UK, have found more evidence for a link between Bisphenol A exposure (BPA, a chemical commonly used in plastic food containers) and cardiovascular disease. The team analysed new US population data and their results are published by the online journal, PLoS ONE.