Body

Discovery of a gene that controls 3 different diseases

An international research consortium led by the Universitat Autònoma de Barcelona (UAB), the CIBERER and the University of Wurzburg (Germany) has discovered a gene that can cause three totally different diseases, depending on how it is altered.

Patient centered medical home helps assess social health determinants and promote health

(Boston) - Physicians from the Departments of Pediatrics and Family Medicine at Boston Medical Center (BMC) and Boston University School of Medicine (BUSM) are proposing that current pediatric guidelines and practices could be implemented within a Patient Centered Medical Home model to address social determinants of health. The article, published in the Journal of the American Medical Association (JAMA), also suggests that these guidelines could reduce socioeconomic disparities in health care for all patients.

Reviving a foe of cancer

April 25, 2013, New York, NY and Oxford, UK – Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don't belong. One protein that keeps healthy cells from behaving this way is a tumor suppressor named p53. This protein stops potentially precancerous cells from dividing and induces suicide in those that are damaged beyond repair. Not surprisingly, p53's critical function is disrupted in most cancers.

Researchers identify key cellular organelle involved in gene silencing

RIVERSIDE, Calif. —RNA molecules, made from DNA, are best known for their role in protein production. MicroRNAs (miRNAs), however, are short (~22) nucleotide RNA sequences found in plants and animals that do not encode proteins but act in gene regulation and, in the process, impact almost all biological processes — from development to physiology to stress response.

BUSM study reveals novel mechanism by which UVA contributes to photoaging of skin

(Boston) – A study conducted by researchers at Boston University School of Medicine (BUSM) provides new evidence that longwave ultraviolet light (UVA) induces a protein that could result in premature skin aging. The findings demonstrate that aspects of photoaging, the process of skin aging by chronic exposure to ultraviolet radiation, could be linked to genetic factors that accelerate the aging process when induced by the environment.

CNIO researchers 'capture' the replication of the human genome for the first time

The Genomic Instability Group led by researcher Óscar Fernández-Capetillo at the Spanish National Cancer Research Centre (CNIO), has for the first time obtained a panoramic photo of the proteins that take part in human DNA division, a process known as replication.

The research article, published today in the journal Cell Reports, is the result of a collaborative study in which other CNIO groups have also participated, including the Proteomics Unit led by Javier Muñoz and the DNA Replication Group led by Juan Méndez.

Study by Worcester Polytechnic Institute professor produces first edition of a bookworm's genome

WORCESTER, Mass. -- It has co-existed quietly with humans for centuries, slurping up the spillage in beer halls and gorging on the sour paste used to bind books. Now the tiny nematode Panagrellus redivivus (P.redivivus) has emerged from relative obscurity with the publication of its complete genetic code. Further study of this worm, which is often called the beer-mat worm or, simply, the microworm, is expected to shed new light on many aspects of animal biology, including the differences between male and female organisms and the unique adaptations of parasitic worms.

With wave of the hand, Carnegie Mellon researchers create touch-based interfaces

PITTSBURGH—Researchers previously have shown that a depth camera system, such as Kinect, can be combined with a projector to turn almost any surface into a touchscreen. But now researchers at Carnegie Mellon University have demonstrated how these touch-based interfaces can be created almost at will, with the wave of a hand.

Leading leukemia experts: High leukemia treatment costs may be harming patients

(WASHINGTON, April 25, 2013) – The increasing cost of treatments for chronic myeloid leukemia (CML) in the United States has reached unsustainably high levels and may be leaving many patients under- or untreated because they cannot afford care, according to a Blood Forum article supported by nearly 120 CML experts from more than 15 countries on five continents and published online today in

Researchers pinpoint how trees play role in smog production

After years of scientific uncertainty and speculation, researchers at the University of North Carolina at Chapel Hill show exactly how trees help create one of society's predominant environmental and health concerns: air pollution.

Study reveals dramatic changes in global attitudes toward domestic violence

WASHINGTON, DC, April 25, 2013 — Global attitudes about domestic violence changed dramatically during the first decade of the 2000s, according to a new University of Michigan study that analyzes data from 26 low- and middle-income countries.

Nigeria had the largest change, with 65 percent of men and 52 percent of women rejecting domestic violence in 2008, compared with 48 percent and 33 percent, respectively, in 2003.

The peculiar life history of Middle American Stenamma ants

Stenamma is a cryptic "leaf-litter" ant genus that occurs in moderately humid to wet forest habitats throughout the Holarctic region, Central America, and part of northwestern South America (Colombia and Ecuador). The genus was thought to be restricted primarily to the temperate zone, but recent collecting efforts have uncovered a large variety of Neotropical forms, which rival the Holarctic species in terms of morphological and behavioral diversity.

New grass hybrid could help reduce the likelihood of flooding

A collaboration of plant and soil scientists from across the UK has shown a grass hybrid species could help reduce the impact of flooding.

The BBSRC-funded scientists, from Rothamsted Research, the James Hutton Institute, Institute of Biological, Environmental and Rural Sciences (IBERS) at Aberystwyth University, Lancaster University and the University of Nottingham, used a hybridised species of grass called perennial ryegrass (Lolium perenne) with a closely related species called meadow fescue (Festuca pratensis).

Probiotics found to reduce hepatic encephalopathy by half - study

Amsterdam, The Netherlands,Thursday 25 April 2013 - Proponents say probiotics could emerge as a treatment plan to manage hepatic encephalopathy (HE) therapy after a new study announced at the International Liver Congress™ 2013 found they significantly reduced development of the notoriously difficult-to-treat disease.

Hepatic encephalopathy is a spectrum of neuropsychiatric abnormalities including personality changes, intellectual impairment and reduced levels of consciousness in patients with liver failure, after exclusion of other known brain disease.

High performance semiconductor spray paint could be a game changer for organic electronics

Researchers at Wake Forest University's Organic Electronics group have come up with a novel solution to one of the biggest technological barriers facing the organic semiconductor industry today. Oana Jurchescu, an assistant professor of physics, and a team of researchers developed a high performance organic semiconductor 'spray paint' that can be applied to large surface areas without losing electric conductivity. This is a potentially game changing technology for a number of reasons.