Body

Scientists have developed an ultra-sensitive test that should enable them to detect signs of a disease in its earliest stages, in research published today in the journal Nature Materials.

The Caterpillar got down off the mushroom and crawled away in the grass, remarking as it went, 'One side will make you grow taller, and the other side will make you grow shorter.'-Alice's Adventures in Wonderland, by Lewis Carroll

UCLA geneticists have identified the mutation responsible for IMAGe syndrome, a rare disorder that stunts infants' growth. The twist? The mutation occurs on the same gene that causes Beckwith-Wiedemann syndrome, which makes cells grow too fast, leading to very large children.

At first glance, it's hard to see how a common house sparrow and a Tyrannosaurus Rex might have anything in common. After all, one is a bird that weighs less than an ounce, and the other is a dinosaur that was the size of a school bus and tipped the scales at more than eight tons.

For all their differences, though, scientists now say that two are more closely related than many believed. A new study, led by Harvard scientists, has shown that modern birds are, essentially, living dinosaurs, with skulls that are remarkably similar to those of their juvenile ancestors.

COLUMBIA, Mo. — For 5,000 years, the Chinese have used a system of medicine based on the flow and balance of positive and negative energies in the body. In this system, the appearance of the tongue is one of the measures used to classify the overall physical status of the body, or zheng. Now, University of Missouri researchers have developed computer software that combines the ancient practices and modern medicine by providing an automated system for analyzing images of the tongue.

Scientists believe they've pinpointed the last crucial piece of the 80-year-old puzzle of how plants "know" when to flower.

Determining the proper time to flower, important if a plant is to reproduce successfully, involves a sequence of molecular events, a plant's circadian clock and sunlight.

Recent recommendations from the U.S. Preventive Services Task Force (USPSTF) advising elimination of routine prostate-specific antigen (PSA) screening for prostate cancer in healthy men are likely to encounter serious pushback from primary care physicians, according to results of a survey by Johns Hopkins investigators.

(SACRAMENTO, Calif.) — UC Davis researchers have found that workers' compensation insurance is not used nearly as much as it should be to cover the nation's multi-billion dollar price tag for workplace illnesses and injuries. Instead, almost 80 percent of these costs are paid by employer-provided health insurance, Medicare, Medicaid, Social Security and other disability funds, employees and other payers.

Cold Spring Harbor, N.Y. – In a study published in the journal Cell on May 24, Cold Spring Harbor Laboratory (CSHL) scientists describe the three-dimensional atomic structure of a human protein bound to a piece of RNA that "guides" the protein's ability to silence genes. The protein, Argonaute-2, is a key player in RNA interference (RNAi), a powerful cellular phenomenon that has important roles in diverse biological processes, including an organism's development.

HOUSTON –HER2 and its epidermal growth factor receptor cousins mobilize a specialized protein to activate a major player in cancer development and sugar metabolism, scientists report in the May 25 issue of Cell.

This chain of events, the scientists found, promotes Herceptin resistance in breast cancer and activation of glucose metabolism (glycolysis), which cancer cells primarily rely on to fuel their growth and survive.

UC Davis mathematicians have helped biologists figure out why platelets, the cells that form blood clots, are the size and shape that they are. Because platelets are important both for healing wounds and in strokes and other conditions, a better understanding of how they form and behave could have wide implications.

Chromosomal deletions in DNA often involve just one of two gene copies inherited from either parent. But scientists haven't known how a deletion in one gene from one parent, called a "hemizygous" deletion, can contribute to cancer.

AMHERST, Mass. – Using camera traps, wildlife researchers including doctoral candidate Jennifer McCarthy and environmental conservation professor Todd Fuller of the University of Massachusetts Amherst recently captured photographs of one of the rarest animals on earth, the Sumatran striped rabbit. They say it may now be found only in two remote national parks on the Indonesian island.

Previously, scientists had been able to create and determine the structure of 'cages' formed by parts of the protein coats that encase other types of vesicles, but this study, published online today in Science, was the first to obtain high-resolution images of complete vesicles, budded from a membrane.

Depicting each copy of COPI as a triangle, the different arrangements of these building blocks become easier to spot.

(Photo Credit: EMBL/M.Faini)

On a marble plate, measuring 40 by 60 centimetres, the name "Yehiel" can be read, followed by further letters which have not yet been deciphered. The Jena Archaeologists believe that the new discovery might be a tomb slab. Antlers, which were found very close to the tomb slab in the rubble gave a clue to the age determination. "The organic material of the antlers could be dated by radiocarbon analysis with certainty to about 390 AD," excavation leader Dr. Dennis Graen of the Jena University explains.

The blueprint of all living beings is stored in their genetic material. In higher organisms this is stored in the well-protected cell nucleus. "Here a kind of copier works around the clock to make copies of the information needed at the time," says first author Jan Peter Siebrasse from the Institute for Physical and Theoretical Chemistry at the University of Bonn. The copies contain the information which the cells need to produce vital enzymes or other cell building materials.